| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13670* | 2021 |
| Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis AD Steele, JG Emsley, PH Özdinler, S Lindquist, JD Macklis Proceedings of the National Academy of Sciences 103 (9), 3416-3421, 2006 | 401 | 2006 |
| IGF-I specifically enhances axon outgrowth of corticospinal motor neurons PH Özdinler, JD Macklis Nature neuroscience 9 (11), 1371-1381, 2006 | 395 | 2006 |
| Pathophysiological and diagnostic implications of cortical dysfunction in ALS N Geevasinga, P Menon, PH Özdinler, MC Kiernan, S Vucic Nature Reviews Neurology 12 (11), 651-661, 2016 | 233 | 2016 |
| Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G93A transgenic ALS mice PH Özdinler, S Benn, TH Yamamoto, M Güzel, RH Brown, JD Macklis Journal of Neuroscience 31 (11), 4166-4177, 2011 | 204 | 2011 |
| Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS B Genç, JH Jara, AKB Lagrimas, P Pytel, RP Roos, MM Mesulam, ... Scientific reports 7 (1), 41765, 2017 | 104 | 2017 |
| Slit2, a branching–arborization factor for sensory axons in the mammalian CNS PH Özdinler, RS Erzurumlu Journal of Neuroscience 22 (11), 4540-4549, 2002 | 95 | 2002 |
| Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease D Fil, A DeLoach, S Yadav, D Alkam, M MacNicol, A Singh, ... Human molecular genetics 26 (4), ddw429, 2017 | 92 | 2017 |
| An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice DP Srivastava, KM Woolfrey, KA Jones, CT Anderson, KR Smith, ... PLoS biology 10 (6), e1001350, 2012 | 89 | 2012 |
| AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS JH Jara, SR Villa, NA Khan, MC Bohn, PH Özdinler Neurobiology of disease 47 (2), 174-183, 2012 | 83 | 2012 |
| A chemoattractant role for NT-3 in proprioceptive axon guidance B Genç, PH Özdinler, AE Mendoza, RS Erzurumlu PLoS biology 2 (12), e403, 2004 | 77 | 2004 |
| Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology M Gautam, JH Jara, N Kocak, LE Rylaarsdam, KD Kim, EH Bigio, ... Acta neuropathologica 137, 47-69, 2019 | 74 | 2019 |
| eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model MV Yasvoina, B Genç, JH Jara, PL Sheets, KA Quinlan, A Milosevic, ... Journal of Neuroscience 33 (18), 7890-7904, 2013 | 74 | 2013 |
| A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity PI Joyce, P Mcgoldrick, RA Saccon, W Weber, P Fratta, SJ West, N Zhu, ... Human molecular genetics 24 (7), 1883-1897, 2015 | 70 | 2015 |
| Could dysregulation of UPS be a common underlying mechanism for cancer and neurodegeneration? Lessons from UCHL1 JH Jara, DD Frank, PH Özdinler Cell biochemistry and biophysics 67, 45-53, 2013 | 70 | 2013 |
| Corticospinal motor neurons are susceptible to increased ER stress and display profound degeneration in the absence of UCHL1 function JH Jara, B Genç, GA Cox, MC Bohn, RP Roos, JD Macklis, E Ulupınar, ... Cerebral cortex 25 (11), 4259-4272, 2015 | 68 | 2015 |
| Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms M Gautam, JH Jara, G Sekerkova, MV Yasvoina, M Martina, PH Özdinler Human molecular genetics 25 (6), 1074-1087, 2016 | 67 | 2016 |
| Regulation of neurotrophin‐induced axonal responses via Rho GTPases PH Özdi̇nler, RS Erzurumlu Journal of Comparative Neurology 438 (4), 377-387, 2001 | 62 | 2001 |
| MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology JH Jara, M Gautam, N Kocak, EF Xie, Q Mao, EH Bigio, PH Özdinler Journal of neuroinflammation 16, 1-16, 2019 | 60 | 2019 |
| Evidence for an early innate immune response in the motor cortex of ALS JH Jara, B Genç, MJ Stanford, P Pytel, RP Roos, S Weintraub, ... Journal of neuroinflammation 14, 1-20, 2017 | 56 | 2017 |