RIP2 filament formation is required for NOD2 dependent NF-κB signalling E Pellegrini, A Desfosses, A Wallmann, WM Schulze, K Rehbein, P Mas, ... Nature communications 9 (1), 4043, 2018 | 64 | 2018 |
Direct cryocooling of naked crystals: are cryoprotection agents always necessary? E Pellegrini, D Piano, MW Bowler Acta Crystallographica Section D: Biological Crystallography 67 (10), 902-906, 2011 | 58 | 2011 |
Inducing phase changes in crystals of macromolecules: Status and perspectives for controlled crystal dehydration S Russi, DH Juers, J Sanchez-Weatherby, E Pellegrini, E Mossou, ... Journal of Structural Biology 175 (2), 236-243, 2011 | 56 | 2011 |
Structural basis for the subversion of MAP kinase signaling by an intrinsically disordered parasite secreted agonist E Pellegrini, A Palencia, L Braun, U Kapp, A Bougdour, H Belrhali, ... Structure 25 (1), 16-26, 2017 | 53 | 2017 |
α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction Y Jin, D Bhattasali, E Pellegrini, SM Forget, NJ Baxter, MJ Cliff, ... Proceedings of the National Academy of Sciences 111 (34), 12384-12389, 2014 | 51 | 2014 |
Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation E Pellegrini, L Signor, S Singh, E Boeri Erba, S Cusack PloS one 12 (5), e0177161, 2017 | 42 | 2017 |
Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation P Juyoux, I Galdadas, D Gobbo, J von Velsen, M Pelosse, M Tully, ... Science 381 (6663), 1217-1225, 2023 | 16 | 2023 |
A GAP‐GTPase‐GDP‐Pi Intermediate Crystal Structure Analyzed by DFT Shows GTP Hydrolysis Involves Serial Proton Transfers RW Molt Jr, E Pellegrini, Y Jin Chemistry–A European Journal 25 (36), 8484-8488, 2019 | 16 | 2019 |
Assessing the Influence of Mutation on GTPase Transition States by Using X‐ray Crystallography, 19F NMR, and DFT Approaches Y Jin, RW Molt Jr, E Pellegrini, MJ Cliff, MW Bowler, NGJ Richards, ... Angewandte Chemie International Edition 56 (33), 9732-9735, 2017 | 12 | 2017 |
Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface M Lethier, K Huard, M Hons, A Favier, B Brutscher, EB Erba, DW Abbott, ... Life Science Alliance 6 (11), 2023 | 5 | 2023 |
Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex E Dubiez, E Pellegrini, MF Brask, W Garland, AE Foucher, K Huard, ... Cell Reports 43 (1), 2024 | 3 | 2024 |
4-Anilinoquinazoline Derivatives as the First Potent NOD1-RIPK2 Signaling Pathway Inhibitors at the Nanomolar Range A Barczyk, P Six, M Rivoal, C Devos, X Dezitter, MJ Cornu-Choi, K Huard, ... Journal of Medicinal Chemistry, 2024 | 1 | 2024 |
4-anilinoquinazoline derivatives as the first potent NOD1-RIPK2 signaling pathway inhibitors at the nanomolar range with potential anti-inflammatory activity A BARCZYK, M RIVOAL, C DEVOS, X DEZITTER, MJ CORNU-CHOI, ... | 1 | 2024 |
Metal fluorides-multi-functional tools for the study of phosphoryl transfer enzymes E Pellegrini, P Juyoux, J von Velsen, N Baxter, Y Jin, H Dannatt, M Cliff, ... bioRxiv, 2024.03. 25.586559, 2024 | | 2024 |
The MAP2Ks can use ADP to phosphorylate and activate their substrate MAPKs in vitro P Juyoux, J von Velsen, E Pellegrini, MW Bowler bioRxiv, 2024.02. 22.581546, 2024 | | 2024 |
Structural analysis shows that the BIR2 domain of E3 ligase XIAP binds across the RIP2 kinase dimer interface M Lethier, M Hons, A Favier, B Brutscher, EB Erba, S Cusack, E Pellegrini bioRxiv, 2022.10. 14.512215, 2022 | | 2022 |
Dissection of Enzymatic Phosphoryl Transfer: from Substrate Recognition to the Transition state E Pellegrini University of Sheffield, 2013 | | 2013 |