Directed evolution of the TALE N-terminal domain for recognition of all 5′ bases BM Lamb, AC Mercer, CF Barbas III Nucleic acids research 41 (21), 9779-9785, 2013 | 189 | 2013 |
Chimeric TALE recombinases with programmable DNA sequence specificity AC Mercer, T Gaj, RP Fuller, CF Barbas III Nucleic acids research 40 (21), 11163-11172, 2012 | 180 | 2012 |
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification JL Meier, AC Mercer, H Rivera, MD Burkart Journal of the American Chemical Society 128 (37), 12174-12184, 2006 | 143 | 2006 |
The ubiquitous carrier protein—a window to metabolite biosynthesis AC Mercer, MD Burkart Natural product reports 24 (4), 750-773, 2007 | 142 | 2007 |
Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase CA Gersbach, T Gaj, RM Gordley, AC Mercer, CF Barbas III Nucleic acids research 39 (17), 7868-7878, 2011 | 130 | 2011 |
In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues KM Clarke, AC Mercer, JJ La Clair, MD Burkart Journal of the American Chemical Society 127 (32), 11234-11235, 2005 | 120 | 2005 |
Structure-guided reprogramming of serine recombinase DNA sequence specificity T Gaj, AC Mercer, CA Gersbach, RM Gordley, CF Barbas III Proceedings of the National Academy of Sciences 108 (2), 498-503, 2011 | 88 | 2011 |
A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells T Gaj, AC Mercer, SJ Sirk, HL Smith, CF Barbas III Nucleic acids research 41 (6), 3937-3946, 2013 | 75 | 2013 |
Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors AC Mercer, T Gaj, SJ Sirk, BM Lamb, CF Barbas III ACS synthetic biology 3 (10), 723-730, 2014 | 71 | 2014 |
Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies S Rajan, MR Kierny, A Mercer, J Wu, A Tovchigrechko, H Wu, ... Communications Biology 1 (1), 5, 2018 | 38 | 2018 |
Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign T Gaj, SJ Sirk, RD Tingle, AC Mercer, MC Wallen, CF Barbas III Journal of the American Chemical Society 136 (13), 5047-5056, 2014 | 35 | 2014 |
Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes JL Meier, AC Mercer, MD Burkart Journal of the American Chemical Society 130 (16), 5443-5445, 2008 | 35 | 2008 |
Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants SJ Sirk, T Gaj, A Jonsson, AC Mercer, CF Barbas III Nucleic acids research 42 (7), 4755-4766, 2014 | 30 | 2014 |
In vivo modification of native carrier protein domains AC Mercer, JL Meier, JW Torpey, MD Burkart ChemBioChem 10 (6), 1091-1100, 2009 | 28 | 2009 |
Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli AC Mercer, JL Meier, GH Hur, AR Smith, MD Burkart Bioorganic & medicinal chemistry letters 18 (22), 5991-5994, 2008 | 28 | 2008 |
Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells YB Johari, AC Mercer, Y Liu, AJ Brown, DC James Biotechnology and Bioengineering 118 (5), 2001-2015, 2021 | 14 | 2021 |
Fluorescent Multiplex Analysis of Carrier Protein Post‐Translational Modification AC Mercer, JJ La Clair, MD Burkart ChemBioChem 6 (8), 1335-1337, 2005 | 14 | 2005 |
Structure of the AAVhu. 37 capsid by cryoelectron microscopy JT Kaelber, SA Yost, KA Webber, E Firlar, Y Liu, O Danos, AC Mercer Acta Crystallographica Section F: Structural Biology Communications 76 (2 …, 2020 | 13 | 2020 |
GluK2 Is a Target for Gene Therapy in Drug‐Resistant Temporal Lobe Epilepsy C Boileau, S Deforges, A Peret, D Scavarda, F Bartolomei, A Giles, ... Annals of Neurology 94 (4), 745-761, 2023 | 10 | 2023 |
Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors BS Hollidge, HB Carroll, R Qian, ML Fuller, AR Giles, AC Mercer, ... Frontiers in Neurology 13, 1051559, 2022 | 9 | 2022 |