| A transmembrane helix dimer: structure and implications KR MacKenzie, JH Prestegard, DM Engelman Science 276 (5309), 131-133, 1997 | 1187 | 1997 |
| The glia-neuron lactate shuttle and elevated ROS promote lipid synthesis in neurons and lipid droplet accumulation in glia via APOE/D L Liu, KR MacKenzie, N Putluri, M Maletić-Savatić, HJ Bellen Cell metabolism 26 (5), 719-737. e6, 2017 | 469 | 2017 |
| Folding and stability of α-helical integral membrane proteins KR MacKenzie Chemical reviews 106 (5), 1931-1977, 2006 | 247 | 2006 |
| Quantitative real-time imaging of glutathione X Jiang, J Chen, A Bajić, C Zhang, X Song, SL Carroll, ZL Cai, M Tang, ... Nature communications 8 (1), 16087, 2017 | 242 | 2017 |
| Structural organization of the pentameric transmembrane alpha‐helices of phospholamban, a cardiac ion channel. IT Arkin, PD Adams, KR MacKenzie, MA Lemmon, AT Brünger, ... The EMBO Journal 13 (20), 4757-4764, 1994 | 241 | 1994 |
| Structure-based prediction of the stability of transmembrane helix–helix interactions: the sequence dependence of glycophorin A dimerization KR MacKenzie, DM Engelman Proceedings of the National Academy of Sciences 95 (7), 3583-3590, 1998 | 177 | 1998 |
| Complex of calmodulin with a ryanodine receptor target reveals a novel, flexible binding mode AA Maximciuc, JA Putkey, Y Shamoo, KR MacKenzie Structure 14 (10), 1547-1556, 2006 | 161 | 2006 |
| Acetylation Disfavors Tau Phase Separation JC Ferreon, A Jain, KJ Choi, PS Tsoi, KR MacKenzie, SY Jung, ... International journal of molecular sciences 19 (5), 1360, 2018 | 159 | 2018 |
| Modulation of glycophorin A transmembrane helix interactions by lipid bilayers: molecular dynamics calculations HI Petrache, A Grossfield, KR MacKenzie, DM Engelman, TB Woolf Journal of molecular biology 302 (3), 727-746, 2000 | 148 | 2000 |
| Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactions IC Dews, KR MacKenzie Proceedings of the National Academy of Sciences 104 (52), 20782-20787, 2007 | 145 | 2007 |
| Sequence-specific dimerization of the transmembrane domain of the “BH3-only” protein BNIP3 in membranes and detergent ES Sulistijo, TM Jaszewski, KR MacKenzie Journal of Biological Chemistry 278 (51), 51950-51956, 2003 | 130 | 2003 |
| Reversible reaction-based fluorescent probe for real-time imaging of glutathione dynamics in mitochondria J Chen, X Jiang, C Zhang, KR MacKenzie, F Stossi, T Palzkill, MC Wang, ... ACS sensors 2 (9), 1257-1261, 2017 | 113 | 2017 |
| Association energetics of membrane spanning α-helices KR MacKenzie, KG Fleming Current opinion in structural biology 18 (4), 412-419, 2008 | 99 | 2008 |
| Changes in apparent free energy of helix–helix dimerization in a biological membrane due to point mutations MT Duong, TM Jaszewski, KG Fleming, KR MacKenzie Journal of molecular biology 371 (2), 422-434, 2007 | 92 | 2007 |
| Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix–helix interactions ES Sulistijo, KR MacKenzie Journal of molecular biology 364 (5), 974-990, 2006 | 91 | 2006 |
| Soil organic matter attenuates the efficacy of flavonoid-based plant-microbe communication I Del Valle, TM Webster, HY Cheng, JE Thies, A Kessler, MK Miller, ... Science Advances 6 (5), eaax8254, 2020 | 88 | 2020 |
| Structural basis for dimerization of the BNIP3 transmembrane domain ES Sulistijo, KR MacKenzie Biochemistry 48 (23), 5106-5120, 2009 | 79 | 2009 |
| Site-directed dichroism as a method for obtaining rotational and orientational constraints for oriented polymers IT Arkin, KR MacKenzie, AT Brünger Journal of the American Chemical Society 119 (38), 8973-8980, 1997 | 76 | 1997 |
| The N‐terminal domain of ALS‐linked TDP‐43 assembles without misfolding PS Tsoi, KJ Choi, PG Leonard, A Sizovs, MM Moosa, KR MacKenzie, ... Angewandte Chemie 129 (41), 12764-12767, 2017 | 70 | 2017 |
| Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization R Sharma, KJ Choi, MD Quan, S Sharma, B Sankaran, H Park, A LaGrone, ... Nature communications 12 (1), 5579, 2021 | 65 | 2021 |
Donald EngelmanProfessor of Molecular Biophysics and Biochemistry, YaleVerified email at yale.edu
