| Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation MS Singh, P Charbel Issa, R Butler, C Martin, DM Lipinski, S Sekaran, ... Proceedings of the National Academy of Sciences 110 (3), 1101-1106, 2013 | 305 | 2013 |
| Clinical applications of retinal gene therapy DM Lipinski, M Thake, RE MacLaren Progress in retinal and eye research 32, 22-47, 2013 | 139 | 2013 |
| Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo T Tolmachova, OE Tolmachov, AR Barnard, SR de Silva, DM Lipinski, ... Journal of molecular medicine 91, 825-837, 2013 | 102 | 2013 |
| CNTF gene therapy confers lifelong neuroprotection in a mouse model of human retinitis pigmentosa DM Lipinski, AR Barnard, MS Singh, C Martin, EJ Lee, WIL Davies, ... Molecular Therapy 23 (8), 1308-1319, 2015 | 88 | 2015 |
| Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration PC Issa, MS Singh, DM Lipinski, NV Chong, FC Delori, AR Barnard, ... Investigative ophthalmology & visual science 53 (2), 1066-1075, 2012 | 70 | 2012 |
| Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD CA Reid, ER Nettesheim, TB Connor, DM Lipinski Scientific reports 8 (1), 11763, 2018 | 69 | 2018 |
| Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina P Charbel Issa, SR De Silva, DM Lipinski, MS Singh, A Mouravlev, Q You, ... PloS one 8 (4), e60361, 2013 | 57 | 2013 |
| Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4−/− mouse and bipolar cells in the rd1 mouse and human retina ex vivo SR De Silva, P Charbel Issa, MS Singh, DM Lipinski, AO Barnea-Cramer, ... Gene therapy 23 (11), 767-774, 2016 | 43 | 2016 |
| miRNA-mediated post-transcriptional silencing of transgenes leads to increased adeno-associated viral vector yield and targeting specificity CA Reid, SL Boye, WW Hauswirth, DM Lipinski Gene Therapy 24 (8), 462-469, 2017 | 41 | 2017 |
| Assessment of cone survival in response to CNTF, GDNF, and VEGF165b in a novel ex vivo model of end-stage retinitis pigmentosa DM Lipinski, MS Singh, RE MacLaren Investigative ophthalmology & visual science 52 (10), 7340-7346, 2011 | 41 | 2011 |
| Improvement of photoreceptor targeting via intravitreal delivery in mouse and human retina using combinatory rAAV2 capsid mutant vectors CA Reid, KJ Ertel, DM Lipinski Investigative ophthalmology & visual science 58 (14), 6429-6439, 2017 | 40 | 2017 |
| Presynaptic expression of LRIT3 transsynaptically organizes the postsynaptic glutamate signaling complex containing TRPM1 N Hasan, G Pangeni, CA Cobb, TA Ray, ER Nettesheim, KJ Ertel, ... Cell reports 27 (11), 3107-3116. e3, 2019 | 39 | 2019 |
| Vesicular Stomatitis Virus Glycoprotein–and Venezuelan Equine Encephalitis Virus-Derived Glycoprotein–Pseudotyped Lentivirus Vectors Differentially Transduce Corneal … DM Lipinski, AR Barnard, PC Issa, MS Singh, SR De Silva, A Trabalza, ... Human gene therapy 25 (1), 50-62, 2014 | 27 | 2014 |
| A destabilizing domain allows for fast, noninvasive, conditional control of protein abundance in the mouse eye–implications for ocular gene therapy S Datta, M Renwick, VQ Chau, F Zhang, ER Nettesheim, DM Lipinski, ... Investigative ophthalmology & visual science 59 (12), 4909-4920, 2018 | 24 | 2018 |
| Small and micro-scale recombinant adeno-associated virus production and purification for ocular gene therapy applications CA Reid, DM Lipinski Retinal Gene Therapy: Methods and Protocols, 19-31, 2018 | 22 | 2018 |
| Validating a low-cost laser speckle contrast imaging system as a quantitative tool for assessing retinal vascular function DD Patel, DM Lipinski Scientific reports 10 (1), 7177, 2020 | 21 | 2020 |
| Acid ceramidase deficiency in mice leads to severe ocular pathology and visual impairment PS Fabian, BS Sajdak, J Sikora, AE Salmon, MS Nagree, J Gurka, ... The American Journal of Pathology 189 (2), 320-338, 2019 | 21 | 2019 |
| AAV-mediated gene transfer of human X-linked inhibitor of apoptosis protects against oxidative cell death in human RPE cells H Shan, D Ji, AR Barnard, DM Lipinski, Q You, EJ Lee, TA Kamalden, ... Investigative Ophthalmology & Visual Science 52 (13), 9591-9597, 2011 | 21 | 2011 |
| Characterization of a dominant cone degeneration in a green fluorescent protein–reporter mouse with disruption of loci associated with human dominant retinal dystrophy DM Lipinski, M Yusuf, AR Barnard, C Damant, PC Issa, MS Singh, E Lee, ... Investigative ophthalmology & visual science 52 (9), 6617-6623, 2011 | 17 | 2011 |
| Systemic vascular transduction by capsid mutant adeno-associated virus after intravenous injection DM Lipinski, CA Reid, SL Boye, JJ Peterson, X Qi, SE Boye, ME Boulton, ... Human gene therapy 26 (11), 767-776, 2015 | 14 | 2015 |
Robert E MacLarenUniversity of OxfordVerified email at eye.ox.ac.uk