Transporters in drug development: 2018 ITC recommendations for transporters of emerging clinical importance MJ Zamek‐Gliszczynski, ME Taub, PP Chothe, X Chu, KM Giacomini, ... Clinical Pharmacology & Therapeutics 104 (5), 890-899, 2018 | 227 | 2018 |
Antiapoptotic properties of α-crystallin–derived peptide chaperones and characterization of their uptake transporters in human RPE cells PG Sreekumar, P Chothe, KK Sharma, R Baid, U Kompella, C Spee, ... Investigative ophthalmology & visual science 54 (4), 2787-2798, 2013 | 59 | 2013 |
Identification of novel breast cancer resistance protein (BCRP) inhibitors by virtual screening Y Pan, PP Chothe, PW Swaan Molecular Pharmaceutics 10 (4), 1236-1248, 2013 | 47 | 2013 |
Sodium-dependent vitamin C transporter SVCT2: expression and function in bone marrow stromal cells and in osteogenesis S Fulzele, P Chothe, R Sangani, N Chutkan, M Hamrick, M Bhattacharyya, ... Stem Cell Research 10 (1), 36-47, 2013 | 45 | 2013 |
Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2) PP Chothe, PW Swaan Biochemical Journal 459 (2), 301-312, 2014 | 41 | 2014 |
Spectrophotometric method for the estimation of oxcarbazepine in tablets C Ramaa, P Chothe, A Naik, V Kadam Indian journal of pharmaceutical sciences 68 (2), 2006 | 32 | 2006 |
Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841 P Chothe, N Singh, V Ganapathy American Journal of Physiology-Cell Physiology 300 (6), C1260-C1269, 2011 | 31 | 2011 |
The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans F Storelli, M Yin, AR Kumar, MK Ladumor, R Evers, PP Chothe, ... Pharmacology & Therapeutics 238, 108271, 2022 | 29 | 2022 |
Evaluation of the interplay between uptake transport and CYP3A4 induction in micropatterned cocultured hepatocytes A Moore, PP Chothe, H Tsao, N Hariparsad Drug Metabolism and Disposition 44 (12), 1910-1919, 2016 | 26 | 2016 |
Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells PP Chothe, N Chutkan, R Sangani, KH Wenger, PD Prasad, ... The spine journal 13 (5), 549-557, 2013 | 25 | 2013 |
Quantitative prediction of CYP3A4 induction: impact of measured, free, and intracellular perpetrator concentrations from human hepatocyte induction studies on drug-drug … Y Sun, PP Chothe, JE Sager, H Tsao, A Moore, L Laitinen, N Hariparsad Drug Metabolism and Disposition 45 (6), 692-705, 2017 | 23 | 2017 |
Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers PP Chothe, LC Czuba, RH Moore, PW Swaan Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (3), 645-653, 2018 | 19 | 2018 |
Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells PP Chothe, SV Thakkar, JP Gnana-Prakasam, S Ananth, DR Hinton, ... Investigative Ophthalmology & Visual Science 51 (1), 413-420, 2010 | 19 | 2010 |
Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2) PP Chothe, LC Czuba, EN Ayewoh, PW Swaan Molecular Pharmaceutics 16 (8), 3569-3576, 2019 | 17 | 2019 |
Transmembrane domain V plays a stabilizing role in the function of human bile acid transporter SLC10A2 RH Moore, P Chothe, PW Swaan Biochemistry 52 (30), 5117-5124, 2013 | 15 | 2013 |
Regulation of proton‐coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate BR Bozard, PP Chothe, A Tawfik, C Williams, S Fulzele, PD Prasad, ... Glia 60 (3), 333-342, 2012 | 14 | 2012 |
Stability assessment of donepezil hydrochloride using validated RP-HPLC Method PP Chothe, RC Subramanian, VJ Kadam Research Journal of Pharmaceutical, Biological and Chemical Sciences 1 (3), 296, 2010 | 14 | 2010 |
International transporter consortium. Transporters in drug development: 2018 ITC recommendations for transporters of emerging clinical importance MJ Zamek-Gliszczynski, ME Taub, PP Chothe, X Chu, KM Giacomini, ... Clin Pharmacol Ther 104 (5), 890-9, 2018 | 12 | 2018 |
Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis PP Chothe, JP Gnana-Prakasam, S Ananth, PM Martin, R Kannan, ... Biochemical and biophysical research communications 405 (2), 244-249, 2011 | 12 | 2011 |
Spectrophotometric estimation of Sildenafil citrate in tablets BS Kuchekar, SV Thakkar, PP Chothe, MR Hiremath, DB Shinde Indian journal of Pharmaceutical sciences 67 (6), 749-751, 2005 | 12 | 2005 |