| Click chemistry: diverse chemical function from a few good reactions HC Kolb, MG Finn, KB Sharpless Angewandte Chemie International Edition 40 (11), 2004-2021, 2001 | 18038 | 2001 |
| Catalytic asymmetric dihydroxylation HC Kolb, MS VanNieuwenhze, KB Sharpless Chemical Reviews 94 (8), 2483-2547, 1994 | 4890 | 1994 |
| The growing impact of click chemistry on drug discovery HC Kolb, KB Sharpless Drug discovery today 8 (24), 1128-1137, 2003 | 4266 | 2003 |
| “On water”: unique reactivity of organic compounds in aqueous suspension S Narayan, J Muldoon, MG Finn, VV Fokin, HC Kolb, KB Sharpless Angewandte Chemie 117 (21), 3339-3343, 2005 | 1991 | 2005 |
| Click‐Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen HC Kolb, MG Finn, KB Sharpless Angewandte Chemie 113 (11), 2056-2075, 2001 | 1685 | 2001 |
| Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807 DT Chien, S Bahri, AK Szardenings, JC Walsh, F Mu, MY Su, WR Shankle, ... Journal of Alzheimer's Disease 34 (2), 457-468, 2013 | 765 | 2013 |
| Inhibitors of HIV-1 protease by using in situ click chemistry M Whiting, J Muldoon, YC Lin, SM Silverman, W Lindstrom, AJ Olson, ... Angewandte Chemie (International Ed. in English) 45 (9), 1435-1439, 2006 | 678 | 2006 |
| Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics CC Lee, G Sui, A Elizarov, CJ Shu, YS Shin, AN Dooley, J Huang, ... Science 310 (5755), 1793-1796, 2005 | 671 | 2005 |
| In situ click chemistry: enzyme inhibitors made to their own specifications R Manetsch, A Krasiński, Z Radić, J Raushel, P Taylor, KB Sharpless, ... Journal of the American Chemical Society 126 (40), 12809-12818, 2004 | 607 | 2004 |
| [18F] T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease CF Xia, J Arteaga, G Chen, U Gangadharmath, LF Gomez, D Kasi, C Lam, ... Alzheimer's & Dementia 9 (6), 666-676, 2013 | 556 | 2013 |
| The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities C WalshJoseph, C KolbHartmuth Antioxidants & redox signaling, 2014 | 475 | 2014 |
| In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors A Krasiński, Z Radić, R Manetsch, J Raushel, P Taylor, KB Sharpless, ... Journal of the American Chemical Society 127 (18), 6686-6692, 2005 | 466 | 2005 |
| Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation Y Bourne, HC Kolb, Z Radić, KB Sharpless, P Taylor, P Marchot Proceedings of the National Academy of Sciences 101 (6), 1449-1454, 2004 | 414 | 2004 |
| A simplified procedure for the stereospecific transformation of 1, 2-diols into epoxides HC Kolb, KB Sharpless Tetrahedron 48 (48), 10515-10530, 1992 | 408 | 1992 |
| Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease S Janelidze, E Stomrud, R Smith, S Palmqvist, N Mattsson, DC Airey, ... Nature communications 11 (1), 1683, 2020 | 363 | 2020 |
| In situ click chemistry: enzyme‐generated inhibitors of carbonic anhydrase II VP Mocharla, B Colasson, LV Lee, S Röper, KB Sharpless, CH Wong, ... Angewandte Chemie 117 (1), 118-122, 2005 | 340 | 2005 |
| Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD). 1. Kinetics HC Kolb, PG Andersson, KB Sharpless Journal of the American Chemical Society 116 (4), 1278-1291, 1994 | 327 | 1994 |
| Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands GA Crispino, KS Jeong, HC Kolb, ZM Wang, D Xu, KB Sharpless The Journal of Organic Chemistry 58 (15), 3785-3786, 1993 | 326 | 1993 |
| Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808 DT Chien, AK Szardenings, S Bahri, JC Walsh, F Mu, C Xia, WR Shankle, ... Journal of Alzheimer's Disease 38 (1), 171-184, 2014 | 317 | 2014 |
| A highly selective and specific PET tracer for imaging of tau pathologies W Zhang, J Arteaga, DK Cashion, G Chen, U Gangadharmath, LF Gomez, ... Journal of Alzheimer's Disease 31 (3), 601-612, 2012 | 238 | 2012 |