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Matthew Bo Dong
Matthew Bo Dong
Verified email at yale.edu
Title
Cited by
Cited by
Year
High-content CRISPR screening
C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ...
Nature Reviews Methods Primers 2 (1), 1-23, 2022
5162022
Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells
MB Dong, G Wang, RD Chow, L Ye, L Zhu, X Dai, JJ Park, HR Kim, ...
Cell 178 (5), 1189-1204. e23, 2019
2842019
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma
RD Chow, CD Guzman, G Wang, F Schmidt, MW Youngblood, L Ye, ...
Nature neuroscience 20 (10), 1329-1341, 2017
2492017
Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA
S Yuan, L Peng, JJ Park, Y Hu, SC Devarkar, MB Dong, Q Shen, S Wu, ...
Molecular cell 80 (6), 1055-1066. e6, 2020
1882020
In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma
L Ye, JJ Park, MB Dong, Q Yang, RD Chow, L Peng, Y Du, J Guo, X Dai, ...
Nature biotechnology 37 (11), 1302-1313, 2019
1742019
A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ...
Cell metabolism 34 (4), 595-614. e14, 2022
1262022
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity
G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ...
Nature Immunology 20 (11), 1494-1505, 2019
1092019
CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade
G Wang, RD Chow, L Zhu, Z Bai, L Ye, F Zhang, PA Renauer, MB Dong, ...
Cancer discovery 10 (12), 1912-1933, 2020
1062020
Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening
G Wang, RD Chow, L Ye, CD Guzman, X Dai, MB Dong, F Zhang, ...
Science advances 4 (2), eaao5508, 2018
1002018
In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens
RD Chow, G Wang, L Ye, A Codina, HR Kim, L Shen, MB Dong, Y Errami, ...
Nature methods 16 (5), 405-408, 2019
622019
Flow cytometric gating for spleen monocyte and DC subsets: differences in autoimmune NOD mice and with acute inflammation
MB Dong, MJ Rahman, KV Tarbell
Journal of immunological methods 432, 4-12, 2016
402016
Tumor immunology CRISPR screening: present, past, and future
MB Dong, K Tang, X Zhou, JJ Zhou, S Chen
Trends in cancer 8 (3), 210-225, 2022
312022
Diacylglycerol kinase ζ limits B cell antigen receptor–dependent activation of ERK signaling to inhibit early antibody responses
ML Wheeler, MB Dong, R Brink, XP Zhong, AL DeFranco
Science signaling 6 (297), ra91-ra91, 2013
292013
CTLA-4 tail fusion enhances CAR-T antitumor immunity
X Zhou, H Cao, SY Fang, RD Chow, K Tang, M Majety, M Bai, MB Dong, ...
Nature immunology 24 (9), 1499-1510, 2023
232023
Convergent identification and interrogation of tumor-intrinsic factors that modulate cancer immunity in vivo
A Codina, PA Renauer, G Wang, RD Chow, JJ Park, H Ye, K Zhang, ...
Cell systems 8 (2), 136-151. e7, 2019
212019
Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species
L Peng, Z Fang, PA Renauer, A McNamara, JJ Park, Q Lin, X Zhou, ...
Cell Reports 40 (5), 2022
202022
Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2
L Peng, PA Renauer, A Ökten, Z Fang, JJ Park, X Zhou, Q Lin, MB Dong, ...
Cell Reports Medicine 3 (5), 2022
182022
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B. 1.617
L Peng, Y Hu, MC Mankowski, P Ren, RE Chen, J Wei, M Zhao, T Li, ...
Nature communications 13 (1), 1638, 2022
182022
Determinants of divergent adaptive immune responses after airway sensitization with ligands of toll-like receptor 5 or toll-like receptor 9
LM Lee, M Ji, M Sinha, MB Dong, X Ren, Y Wang, CA Lowell, S Ghosh, ...
PLoS One 11 (12), e0167693, 2016
162016
Despite increased type 1 IFN, autoimmune nonobese diabetic mice display impaired dendritic cell response to CpG and decreased nuclear localization of IFN-activated STAT1
MJ Rahman, G Rahir, MB Dong, Y Zhao, KB Rodrigues, C Hotta-Iwamura, ...
The Journal of Immunology 196 (5), 2031-2040, 2016
122016
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