Targeting the NLRP3 inflammasome in inflammatory diseases MSJ Mangan, EJ Olhava, WR Roush, HM Seidel, GD Glick, E Latz Nature reviews Drug discovery 17 (8), 588-606, 2018 | 1804 | 2018 |
Dimers of mitochondrial ATP synthase form the permeability transition pore V Giorgio, S Von Stockum, M Antoniel, A Fabbro, F Fogolari, M Forte, ... Proceedings of the National Academy of Sciences 110 (15), 5887-5892, 2013 | 1060 | 2013 |
Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography NK Sauter, JE Hanson, GD Glick, JH Brown, RL Crowther, SJ Park, ... Biochemistry 31 (40), 9609-9621, 1992 | 456 | 1992 |
Designed signaling aptamers that transduce molecular recognition to changes in fluorescence intensity SD Jhaveri, R Kirby, R Conrad, EJ Maglott, M Bowser, RT Kennedy, ... Journal of the American Chemical Society 122 (11), 2469-2473, 2000 | 361 | 2000 |
Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists X Hu, Y Wang, LY Hao, X Liu, CA Lesch, BM Sanchez, JM Wendling, ... Nature chemical biology 11 (2), 141-147, 2015 | 247 | 2015 |
Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease E Gatza, DR Wahl, AW Opipari, TB Sundberg, P Reddy, C Liu, GD Glick, ... Science translational medicine 3 (67), 67ra8-67ra8, 2011 | 195 | 2011 |
Signaling pathways and effector mechanisms pre-programmed cell death NB Blatt, GD Glick Bioorganic & medicinal chemistry 9 (6), 1371-1384, 2001 | 173 | 2001 |
Effector T cells require fatty acid metabolism during murine graft-versus-host disease CA Byersdorfer, V Tkachev, AW Opipari, S Goodell, J Swanson, ... Blood, The Journal of the American Society of Hematology 122 (18), 3230-3237, 2013 | 163 | 2013 |
Ligand recognition by influenza virus. The binding of bivalent sialosides. GD Glick, PL Toogood, DC Wiley, JJ Skehel, JR Knowles Journal of Biological Chemistry 266 (35), 23660-23669, 1991 | 160 | 1991 |
Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423 KM Johnson, X Chen, A Boitano, L Swenson, AW Opipari, GD Glick Chemistry & biology 12 (4), 485-496, 2005 | 149 | 2005 |
Distinct metabolic programs in activated T cells: opportunities for selective immunomodulation DR Wahl, CA Byersdorfer, JLM Ferrara, AW Opipari Jr, GD Glick Immunological reviews 249 (1), 104-115, 2012 | 141 | 2012 |
Programmed death-1 controls T cell survival by regulating oxidative metabolism V Tkachev, S Goodell, AW Opipari, LY Hao, L Franchi, GD Glick, ... The Journal of Immunology 194 (12), 5789-5800, 2015 | 139 | 2015 |
36° step size of proton‐driven c‐ring rotation in FoF1‐ATP synthase MG Düser, N Zarrabi, DJ Cipriano, S Ernst, GD Glick, SD Dunn, M Börsch The EMBO journal 28 (18), 2689-2696, 2009 | 134 | 2009 |
Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin. NK Sauter, GD Glick, RL Crowther, SJ Park, MB Eisen, JJ Skehel, ... Proceedings of the National Academy of Sciences 89 (1), 324-328, 1992 | 126 | 1992 |
Benzodiazepine-induced superoxide signalsB cell apoptosis: mechanistic insight and potential therapeutic utility NB Blatt, JJ Bednarski, RE Warner, F Leonetti, KM Johnson, A Boitano, ... The Journal of clinical investigation 110 (8), 1123-1132, 2002 | 116 | 2002 |
Molecular recognition of bivalent sialosides by influenza virus GD Glick, JR Knowles Journal of the American Chemical Society 113 (12), 4701-4703, 1991 | 115 | 1991 |
Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity X Hu, X Liu, J Moisan, Y Wang, CA Lesch, C Spooner, RW Morgan, ... Oncoimmunology 5 (12), e1254854, 2016 | 103 | 2016 |
Characterization of the metabolic phenotype of chronically activated lymphocytes DR Wahl, B Petersen, R Warner, BC Richardson, GD Glick, AW Opipari Lupus 19 (13), 1492-1501, 2010 | 102 | 2010 |
Dissecting the behavior of a promiscuous solvate former CP Price, GD Glick, AJ Matzger Angewandte Chemie International Edition 45 (13), 2062-2066, 2006 | 93 | 2006 |
Ligand recognition by murine anti-DNA autoantibodies. II. Genetic analysis and pathogenicity. PC Swanson, RL Yung, NB Blatt, MA Eagan, JM Norris, BC Richardson, ... The Journal of clinical investigation 97 (7), 1748-1760, 1996 | 89 | 1996 |