Articles with public access mandates - Pieter R CullisLearn more
Not available anywhere: 4
The immunostimulatory activity of unmethylated and methylated CpG oligodeoxynucleotide is dependent on their ability to colocalize with TLR9 in late endosomes
SD de Jong, G Basha, KD Wilson, M Kazem, P Cullis, W Jefferies, Y Tam
The Journal of Immunology 184 (11), 6092-6102, 2010
Mandates: Canadian Institutes of Health Research
Synthesis and characterization of hybrid lipid nanoparticles containing gold nanoparticles and a weak base drug
IV Zhigaltsev, YYC Tam, JA Kulkarni, PR Cullis
Langmuir 38 (25), 7858-7866, 2022
Mandates: Canadian Institutes of Health Research
Hepatocyte-targeted delivery of imiquimod reduces hepatitis B virus surface antigen
NAL Fayez, E Rouhollahi, CY Ong, J Wu, A Nguyen, R Böttger, PR Cullis, ...
Journal of Controlled Release 350, 630-641, 2022
Mandates: Swiss National Science Foundation, Canadian Institutes of Health Research …
Tissue microenvironment and cellular imaging
SS Nasseri, SM Grist, S Chen, YY Tam, P Cullis, KC Cheung
2017 IEEE International Electron Devices Meeting (IEDM), 10.7. 1-10.7. 4, 2017
Mandates: Canadian Institutes of Health Research
Available somewhere: 94
Liposomal drug delivery systems: from concept to clinical applications
TM Allen, PR Cullis
Advanced drug delivery reviews 65 (1), 36-48, 2013
Mandates: Canadian Institutes of Health Research
Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo
M Jayaraman, SM Ansell, BL Mui, YK Tam, J Chen, X Du, D Butler, ...
Angewandte Chemie 124 (34), 8657-8661, 2012
Mandates: Canadian Institutes of Health Research
Lipid nanoparticle systems for enabling gene therapies
PR Cullis, MJ Hope
Molecular Therapy 25 (7), 1467-1475, 2017
Mandates: Canadian Institutes of Health Research, Genome Canada, Natural Sciences and …
The current landscape of nucleic acid therapeutics
JA Kulkarni, D Witzigmann, SB Thomson, S Chen, BR Leavitt, PR Cullis, ...
Nature nanotechnology 16 (6), 630-643, 2021
Mandates: Swiss National Science Foundation, Canadian Institutes of Health Research …
Lipid nanoparticles enabling gene therapies: from concepts to clinical utility
JA Kulkarni, PR Cullis, R Van Der Meel
Nucleic acid therapeutics 28 (3), 146-157, 2018
Mandates: Canadian Institutes of Health Research, Netherlands Organisation for …
On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ...
ACS nano 12 (5), 4787-4795, 2018
Mandates: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing
IV Zhigaltsev, N Belliveau, I Hafez, AKK Leung, J Huft, C Hansen, ...
Langmuir 28 (7), 3633-3640, 2012
Mandates: Canadian Institutes of Health Research
Lipid nanoparticle technology for clinical translation of siRNA therapeutics
JA Kulkarni, D Witzigmann, S Chen, PR Cullis, R van der Meel
Accounts of chemical research 52 (9), 2435-2444, 2019
Mandates: Swiss National Science Foundation, Canadian Institutes of Health Research …
Lipid nanoparticles containing siRNA synthesized by microfluidic mixing exhibit an electron-dense nanostructured core
AKK Leung, IM Hafez, S Baoukina, NM Belliveau, IV Zhigaltsev, ...
The Journal of Physical Chemistry C 116 (34), 18440-18450, 2012
Mandates: Canadian Institutes of Health Research
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
S Chen, YYC Tam, PJC Lin, MMH Sung, YK Tam, PR Cullis
Journal of Controlled Release 235, 236-244, 2016
Mandates: Canadian Institutes of Health Research, Genome Canada, Michael Smith …
Microfluidic mixing: a general method for encapsulating macromolecules in lipid nanoparticle systems
AKK Leung, YYC Tam, S Chen, IM Hafez, PR Cullis
The Journal of Physical Chemistry B 119 (28), 8698-8706, 2015
Mandates: Canadian Institutes of Health Research
On the role of helper lipids in lipid nanoparticle formulations of siRNA
JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis
Nanoscale 11 (45), 21733-21739, 2019
Mandates: Swiss National Science Foundation, Canadian Institutes of Health Research …
Lipid nanoparticle technology for therapeutic gene regulation in the liver
D Witzigmann, JA Kulkarni, J Leung, S Chen, PR Cullis, R van der Meel
Advanced drug delivery reviews 159, 344-363, 2020
Mandates: Swiss National Science Foundation, Canadian Institutes of Health Research …
Lipid-based DNA therapeutics: hallmarks of non-viral gene delivery
J Buck, P Grossen, PR Cullis, J Huwyler, D Witzigmann
ACS nano 13 (4), 3754-3782, 2019
Mandates: Swiss National Science Foundation
State‐of‐the‐art design and rapid‐mixing production techniques of lipid nanoparticles for nucleic acid delivery
MJW Evers, JA Kulkarni, R van der Meel, PR Cullis, P Vader, ...
Small methods 2 (9), 1700375, 2018
Mandates: Canadian Institutes of Health Research, Netherlands Organisation for …
Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells
G Basha, TI Novobrantseva, N Rosin, YYC Tam, IM Hafez, MK Wong, ...
Molecular Therapy 19 (12), 2186-2200, 2011
Mandates: Canadian Institutes of Health Research
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