| Involvement of the MKK6-p38γ cascade in γ-radiation-induced cell cycle arrest X Wang, CH McGowan, M Zhao, L He, JS Downey, C Fearns, Y Wang, ... Molecular and cellular biology 20 (13), 4543-4552, 2000 | 353 | 2000 |
| Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen. S Huang, NP Wang, BY Tseng, WH Lee, EH Lee The EMBO journal 9 (6), 1815-1822, 1990 | 268 | 1990 |
| The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. IM Buyse, G Shao, S Huang Proceedings of the National Academy of Sciences 92 (10), 4467-4471, 1995 | 264 | 1995 |
| Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. S Fears, C Mathieu, N Zeleznik-Le, S Huang, JD Rowley, G Nucifora Proceedings of the National Academy of Sciences 93 (4), 1642-1647, 1996 | 254 | 1996 |
| Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein–methyltransferase superfamily G Steele-Perkins, W Fang, XH Yang, M Van Gele, T Carling, J Gu, ... Genes & development 15 (17), 2250-2262, 2001 | 253 | 2001 |
| Inactivation of a histone methyltransferase by mutations in human cancers KC Kim, L Geng, S Huang Cancer research 63 (22), 7619-7623, 2003 | 248 | 2003 |
| Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily Y Du, T Carling, W Fang, Z Piao, JC Sheu, S Huang Cancer research 61 (22), 8094-8099, 2001 | 240 | 2001 |
| The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression S Huang, G Shao, L Liu Journal of Biological Chemistry 273 (26), 15933-15939, 1998 | 226 | 1998 |
| Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis RB Chadwick, GL Jiang, GA Bennington, B Yuan, CK Johnson, ... Proceedings of the National Academy of Sciences 97 (6), 2662-2667, 2000 | 219 | 2000 |
| Histone methyltransferases, diet nutrients and tumour suppressors S Huang Nature Reviews Cancer 2 (6), 469-476, 2002 | 210 | 2002 |
| RIZ1, but not the Alternative RIZ2 Product of the Same Gene, Is Underexpressed in Breast Cancer, and Forced RIZ1 Expression Causes G2-M Cell Cycle Arrest … L He, JX Yu, L Liu, IM Buyse, M Wang, Q Yang, A Nakagawara, ... Cancer research 58 (19), 4238-4244, 1998 | 192 | 1998 |
| A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product S Huang, WH Lee, EYHP Lee Nature 350 (6314), 160-162, 1991 | 185 | 1991 |
| PRDM5 is silenced in human cancers and has growth suppressive activities Q Deng, S Huang Oncogene 23 (28), 4903-4910, 2004 | 141 | 2004 |
| The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter L Liu, G Shao, G Steele-Perkins, S Huang Journal of Biological Chemistry 272 (5), 2984-2991, 1997 | 130 | 1997 |
| Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1 G Jiang, L Liu, IM Buyse, D Simon, S Huang International journal of cancer 83 (4), 541-546, 1999 | 128 | 1999 |
| Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability Z Piao, W Fang, S Malkhosyan, H Kim, A Horii, M Perucho, S Huang Cancer research 60 (17), 4701-4704, 2000 | 121 | 2000 |
| The yin-yang of PR-domain family genes in tumorigenesis GL Jiang, S Huang Histology and histopathology 15 (1), 109-117, 2000 | 121 | 2000 |
| Blimp-1 is the murine homolog of the human transcriptional repressor PRDI-BF1 S Huang Cell 78 (1), 9-10, 1994 | 120 | 1994 |
| Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5 Z Duan, RE Person, HH Lee, S Huang, J Donadieu, R Badolato, ... Molecular and cellular biology 27 (19), 6889-6902, 2007 | 116 | 2007 |
| Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13–p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the … W Fang, Z Piao, D Simon, JC Sheu, S Huang Genes, Chromosomes and Cancer 28 (3), 269-275, 2000 | 113 | 2000 |
Albert de la ChapelleProfessor, Ohio State UniversityVerified email at osumc.edu