Mike Tyers

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Kara DolinskiPrinceton UniversityVerified email at princeton.edu
Jan WildenhainManager Data Analytics Consulting at EPAMVerified email at epam.com
anne-claude gingrasLunenfeld-Tanenbaum Research Institute; University of TorontoVerified email at lunenfeld.ca
Michael LivstoneScientific Data Curation Lead, RegeneronVerified email at regeneron.com
Bruce FutcherProfessor of Molecular Genetics and Microbiology, Stony Brook UniversityVerified email at stonybrook.edu
Charles BooneProfessor, Donnelly Centre, University of TorontoVerified email at utoronto.ca
Alexey NesvizhskiiGodfrey D. Stobbe Professor of Bioinformatics @ University of MichiganVerified email at umich.edu
Hyungwon ChoiVerified email at nus.edu.sg
Gary BaderProfessor of Molecular Genetics and Computer Science, The Donnelly Centre, University of TorontoVerified email at utoronto.ca
Julie D Forman-KayHospital for Sick Children; University of TorontoVerified email at sickkids.ca
Corey NislowProfessor, CRC Tier 1 in Translational Genomics, University of British ColumbiaVerified email at ubc.ca
Guri Nina GiaeverAssociate Professor, Faculty of Pharmaceutical Sciences, University of British ColumbiaVerified email at UBC.ca
Derek F CeccarelliLunenfeld-Tanenbaum Research InstituteVerified email at lunenfeld.ca
J.Wade HarperProfessor of Cell BiologyVerified email at hms.harvard.edu
Daniel DurocherThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of MolecularVerified email at lunenfeld.ca
Mark D. RobinsonFull Professor of Statistical Genomics, University of ZurichVerified email at mls.uzh.ch
Christopher HogueIndependentVerified email at blueprint.org
Timothy R. HughesUniversity of TorontoVerified email at utoronto.ca
Piers D NashUniversity of ChicagoVerified email at uchicago.edu
Eric D BrownProfessor of Biochemistry, McMaster UniversityVerified email at mcmaster.ca

Mike Tyers

The Hospital for Sick Children

Verified email at sickkids.ca

cell growth and division systems and synthetic biology chemical biology ubiquitin-proteasome system infectious disease


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BioGRID: a general repository for interaction datasets C Stark, BJ Breitkreutz, T Reguly, L Boucher, A Breitkreutz, M Tyers Nucleic acids research 34 (suppl_1), D535-D539, 2006	4637	2006
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry Y Ho, A Gruhler, A Heilbut, GD Bader, L Moore, SL Adams, A Millar, ... Nature 415 (6868), 180-183, 2002	4609	2002
Systematic genetic analysis with ordered arrays of yeast deletion mutants AHY Tong, M Evangelista, AB Parsons, H Xu, GD Bader, N Pagé, ... Science 294 (5550), 2364-2368, 2001	2641	2001
The BioGRID interaction database: 2017 update A Chatr-Aryamontri, R Oughtred, L Boucher, J Rust, C Chang, NK Kolas, ... Nucleic acids research 45 (D1), D369-D379, 2017	2094	2017
From genomics to proteomics M Tyers, M Mann Nature 422 (6928), 193-197, 2003	1682	2003
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex D Skowyra, KL Craig, M Tyers, SJ Elledge, JW Harper Cell 91 (2), 209-219, 1997	1565	1997
The BioGRID interaction database: 2019 update R Oughtred, C Stark, BJ Breitkreutz, J Rust, L Boucher, C Chang, N Kolas, ... Nucleic acids research 47 (D1), D529-D541, 2019	1384	2019
Global analysis of protein phosphorylation in yeast J Ptacek, G Devgan, G Michaud, H Zhu, X Zhu, J Fasolo, H Guo, G Jona, ... Nature 438 (7068), 679-684, 2005	1254	2005
The chemical genomic portrait of yeast: uncovering a phenotype for all genes ME Hillenmeyer, E Fung, J Wildenhain, SE Pierce, S Hoon, W Lee, ... Science 320 (5874), 362-365, 2008	1163	2008
The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions R Oughtred, J Rust, C Chang, BJ Breitkreutz, C Stark, A Willems, ... Protein Science 30 (1), 187-200, 2021	1139	2021
Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles CJ Roberts, B Nelson, MJ Marton, R Stoughton, MR Meyer, HA Bennett, ... Science 287 (5454), 873-880, 2000	1136	2000
The BioGRID interaction database: 2011 update C Stark, BJ Breitkreutz, A Chatr-Aryamontri, L Boucher, R Oughtred, ... Nucleic acids research 39 (suppl_1), D698-D704, 2010	1066	2010
The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation R Visintin, K Craig, ES Hwang, S Prinz, M Tyers, A Amon Molecular cell 2 (6), 709-718, 1998	992	1998
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication P Nash, X Tang, S Orlicky, Q Chen, FB Gertler, MD Mendenhall, F Sicheri, ... Nature 414 (6863), 514-521, 2001	955	2001
Systematic identification of pathways that couple cell growth and division in yeast P Jorgensen, JL Nishikawa, BJ Breitkreutz, M Tyers Science 297 (5580), 395-400, 2002	942	2002
The BioGRID interaction database: 2008 update BJ Breitkreutz, C Stark, T Reguly, L Boucher, A Breitkreutz, M Livstone, ... Nucleic acids research 36 (suppl_1), D637-D640, 2007	898	2007
SAINT: probabilistic scoring of affinity purification–mass spectrometry data H Choi, B Larsen, ZY Lin, A Breitkreutz, D Mellacheruvu, D Fermin, ZS Qin, ... Nature methods 8 (1), 70-73, 2011	836	2011
BoxPlotR: a web tool for generation of box plots M Spitzer, J Wildenhain, J Rappsilber, M Tyers Nature methods 11 (2), 121-122, 2014	807	2014
The BioGRID interaction database: 2013 update A Chatr-Aryamontri, BJ Breitkreutz, S Heinicke, L Boucher, A Winter, ... Nucleic acids research 41 (D1), D816-D823, 2012	806	2012
A global protein kinase and phosphatase interaction network in yeast A Breitkreutz, H Choi, JR Sharom, L Boucher, V Neduva, B Larsen, ZY Lin, ... Science 328 (5981), 1043-1046, 2010	792	2010

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