Natural products in the process of finding new drug candidates P Vuorela, M Leinonen, P Saikku, P Tammela, JP Rauha, T Wennberg, ... Current medicinal chemistry 11 (11), 1375-1389, 2004 | 462 | 2004 |
Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays L Pohjala, A Utt, M Varjak, A Lulla, A Merits, T Ahola, P Tammela PloS one 6 (12), e28923, 2011 | 306 | 2011 |
Nanofibrillar cellulose wound dressing in skin graft donor site treatment T Hakkarainen, R Koivuniemi, M Kosonen, C Escobedo-Lucea, ... Journal of Controlled Release 244, 292-301, 2016 | 263 | 2016 |
Exploring marine resources for bioactive compounds P Kiuru, MV DʼAuria, CD Muller, P Tammela, H Vuorela, ... Planta medica 80 (14), 1234-1246, 2014 | 248 | 2014 |
Effect of pmt gene overexpression on tropane alkaloid production in transformed root cultures of Datura metel and Hyoscyamus muticus E Moyano, K Jouhikainen, PÈ Tammela, J Palazón, RM Cusidó, MT Piñol, ... Journal of Experimental Botany 54 (381), 203-211, 2003 | 178 | 2003 |
Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles P Tammela, L Laitinen, A Galkin, T Wennberg, R Heczko, H Vuorela, ... Archives of Biochemistry and Biophysics 425 (2), 193-199, 2004 | 161 | 2004 |
Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains CD Cruz, S Shah, P Tammela BMC microbiology 18, 1-9, 2018 | 151 | 2018 |
Betulin-derived compounds as inhibitors of alphavirus replication L Pohjala, S Alakurtti, T Ahola, J Yli-Kauhaluoma, P Tammela Journal of Natural Products 72 (11), 1917-1926, 2009 | 148 | 2009 |
Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade T Rantamäki, L Vesa, H Antila, A Di Lieto, P Tammela, A Schmitt, ... PloS one 6 (6), e20567, 2011 | 140 | 2011 |
Discovery of benzothiazole scaffold-based DNA gyrase B inhibitors M Gjorgjieva, T Tomasic, M Barancokova, S Katsamakas, J Ilas, ... Journal of medicinal chemistry 59 (19), 8941-8954, 2016 | 136 | 2016 |
Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site T Tomasic, S Katsamakas, Z Hodnik, J Ilaš, M Brvar, T Solmajer, ... Journal of medicinal chemistry 58 (14), 5501-5521, 2015 | 130 | 2015 |
Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures J Alvesalo, H Vuorela, P Tammela, M Leinonen, P Saikku, P Vuorela Biochemical pharmacology 71 (6), 735-741, 2006 | 125 | 2006 |
In vitro assay for human toxicity of cereulide, the emetic mitochondrial toxin produced by food poisoning Bacillus cereus EL Jääskeläinen, V Teplova, MA Andersson, LC Andersson, P Tammela, ... Toxicology in Vitro 17 (5-6), 737-744, 2003 | 122 | 2003 |
Aggregating behavior of phenolic compounds—a source of false bioassay results? L Pohjala, P Tammela Molecules 17 (9), 10774-10790, 2012 | 111 | 2012 |
Screening and characterisation of antimicrobial properties of semisynthetic betulin derivatives S Haque, DA Nawrot, S Alakurtti, L Ghemtio, J Yli-Kauhaluoma, ... PLoS One 9 (7), e102696, 2014 | 87 | 2014 |
Screening bioactivity and bioactive constituents of Nordic unifloral honeys A Salonen, V Virjamo, P Tammela, L Fauch, R Julkunen-Tiitto Food chemistry 237, 214-224, 2017 | 78 | 2017 |
Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues N Zidar, S Montalvão, Ž Hodnik, DA Nawrot, A Žula, J Ilaš, D Kikelj, ... Marine drugs 12 (2), 940-963, 2014 | 75 | 2014 |
Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays L Pohjala, P Tammela, SK Samanta, J Yli-Kauhaluoma, P Vuorela Analytical biochemistry 362 (2), 221-228, 2007 | 75 | 2007 |
Marine microalgae: promising source for new bioactive compounds CR De Vera, G Díaz Crespín, A Hernández Daranas, S Montalvão Looga, ... Marine drugs 16 (9), 317, 2018 | 73 | 2018 |
N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation N Zidar, H Macut, T Tomasic, M Brvar, S Montalvao, P Tammela, ... Journal of medicinal chemistry 58 (15), 6179-6194, 2015 | 69 | 2015 |