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Undulating changes in human plasma proteome profiles across the lifespan B Lehallier, D Gate, N Schaum, T Nanasi, SE Lee, H Yousef, ... Nature medicine 25 (12), 1843-1850, 2019 | 627 | 2019 |
Dysregulation of brain and choroid plexus cell types in severe COVID-19 AC Yang, F Kern, PM Losada, MR Agam, CA Maat, GP Schmartz, ... Nature 595 (7868), 565-571, 2021 | 562 | 2021 |
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk AC Yang, RT Vest, F Kern, DP Lee, M Agam, CA Maat, PM Losada, ... Nature 603 (7903), 885-892, 2022 | 502 | 2022 |
Ageing hallmarks exhibit organ-specific temporal signatures N Schaum, B Lehallier, O Hahn, R Pálovics, S Hosseinzadeh, SE Lee, ... Nature 583 (7817), 596-602, 2020 | 453 | 2020 |
Organ aging signatures in the plasma proteome track health and disease HSH Oh, J Rutledge, D Nachun, R Pálovics, O Abiose, P Moran-Losada, ... Nature 624 (7990), 164-172, 2023 | 149 | 2023 |
Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment R Hilker, A Munder, J Klockgether, PM Losada, P Chouvarine, N Cramer, ... Environmental microbiology 17 (1), 29-46, 2015 | 119 | 2015 |
Cortical organoids model early brain development disrupted by 16p11. 2 copy number variants in autism J Urresti, P Zhang, P Moran-Losada, NK Yu, PD Negraes, CA Trujillo, ... Molecular psychiatry 26 (12), 7560-7580, 2021 | 91 | 2021 |
The cystic fibrosis lower airways microbial metagenome PM Losada, P Chouvarine, M Dorda, S Hedtfeld, S Mielke, A Schulz, ... ERJ open research 2 (2), 2016 | 80 | 2016 |
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment N Piehl, L van Olst, A Ramakrishnan, V Teregulova, B Simonton, Z Zhang, ... Cell 185 (26), 5028-5039. e13, 2022 | 77 | 2022 |
Atlas of the aging mouse brain reveals white matter as vulnerable foci O Hahn, AG Foltz, M Atkins, B Kedir, P Moran-Losada, IH Guldner, ... Cell 186 (19), 4117-4133. e22, 2023 | 61 | 2023 |
Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14 S Fischer, J Klockgether, P Morán Losada, P Chouvarine, N Cramer, ... Environmental microbiology reports 8 (2), 227-234, 2016 | 50 | 2016 |
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling M Amar, AB Pramod, NK Yu, VM Herrera, LR Qiu, P Moran-Losada, ... Molecular psychiatry 26 (7), 3586-3613, 2021 | 41 | 2021 |
Limited proteolysis–mass spectrometry reveals aging-associated changes in cerebrospinal fluid protein abundances and structures SR Shuken, J Rutledge, T Iram, PM Losada, EN Wilson, KI Andreasson, ... Nature Aging 2 (5), 379-388, 2022 | 34 | 2022 |
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THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier S Saran, DDH Tran, S Klebba-Färber, P Moran-Losada, L Wiehlmann, ... BMC Cell Biology 14, 1-14, 2013 | 26 | 2013 |
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease Y Jiang, X Zhou, HY Wong, L Ouyang, FCF Ip, VMN Chau, SF Lau, W Wu, ... Nature aging 2 (7), 616-634, 2022 | 25 | 2022 |
Broad transcriptional dysregulation of brain and choroid plexus cell types with COVID-19 AC Yang, F Kern, PM Losada, CA Maat, G Schmartz, T Fehlmann, ... BioRxiv, 2020.10. 22.349415, 2020 | 25 | 2020 |
Filtration and normalization of sequencing read data in whole-metagenome shotgun samples P Chouvarine, L Wiehlmann, P Moran Losada, DS DeLuca, B Tümmler PloS one 11 (10), e0165015, 2016 | 24 | 2016 |
Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics Z He, Y Le Guen, L Liu, J Lee, S Ma, AC Yang, X Liu, J Rutledge, ... The American Journal of Human Genetics 108 (12), 2336-2353, 2021 | 22 | 2021 |