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Hao Wu
Hao Wu
Whitehead Institute, MIT
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Title
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Cited by
Year
Editing DNA methylation in the mammalian genome
XS Liu, H Wu, X Ji, Y Stelzer, X Wu, S Czauderna, J Shu, D Dadon, ...
Cell 167 (1), 233-247. e17, 2016
13162016
Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene
XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ...
Cell 172 (5), 979-992. e6, 2018
4922018
Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease
H Wu, J Luo, H Yu, A Rattner, A Mo, Y Wang, PM Smallwood, B Erlanger, ...
Neuron 81 (1), 103-119, 2014
2222014
PDZ domains of Par-3 as potential phosphoinositide signaling integrators
H Wu, W Feng, J Chen, LN Chan, S Huang, M Zhang
Molecular cell 28 (5), 886-898, 2007
2222007
Molecular basis of Bcl-xL’s target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1
W Feng, S Huang, H Wu, M Zhang
Journal of molecular biology 372 (1), 223-235, 2007
2132007
Complete morphologies of basal forebrain cholinergic neurons in the mouse
H Wu, J Williams, J Nathans
elife 3, e02444, 2014
1772014
Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment
W Feng, H Wu, LN Chan, M Zhang
Journal of Biological Chemistry 283 (34), 23440-23449, 2008
1592008
Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor
R Wang, Z Wei, H Jin, H Wu, C Yu, W Wen, LN Chan, Z Wen, M Zhang
Molecular cell 33 (6), 692-703, 2009
1182009
Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice
X Tang, J Drotar, K Li, CD Clairmont, AS Brumm, AJ Sullins, H Wu, XS Liu, ...
Science translational medicine 11 (503), eaau0164, 2019
1132019
Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
L Pan, H Wu, C Shen, Y Shi, W Jin, J Xia, M Zhang
The EMBO journal 26 (21), 4576-4587, 2007
922007
The Par‐3 NTD adopts a PB1‐like structure required for Par‐3 oligomerization and membrane localization
W Feng, H Wu, LN Chan, M Zhang
The EMBO journal 26 (11), 2786-2796, 2007
842007
Hypoxia‐inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E–deficient mice
A Maier, H Wu, N Cordasic, P Oefner, B Dietel, C Thiele, A Weidemann, ...
The FASEB Journal 31 (11), 4971-4984, 2017
702017
Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling
H Wu, J Williams, J Nathans
Elife 1, e00181, 2012
672012
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein
W Wen, L Chen, H Wu, X Sun, M Zhang, DK Banfield
Molecular biology of the cell 17 (10), 4282-4299, 2006
532006
Parent-of-origin DNA methylation dynamics during mouse development
Y Stelzer, H Wu, Y Song, CS Shivalila, S Markoulaki, R Jaenisch
Cell reports 16 (12), 3167-3180, 2016
412016
Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons
JD Graef, H Wu, C Ng, C Sun, V Villegas, D Qadir, K Jesseman, ...
European Journal of Neuroscience 51 (10), 2143-2157, 2020
342020
Flat mount imaging of mouse skin and its application to the analysis of hair follicle patterning and sensory axon morphology
H Chang, Y Wang, H Wu, J Nathans
Journal of Visualized Experiments: Jove, 51749, 2014
232014
Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome
T Malachowski, KR Chandradoss, R Boya, L Zhou, AL Cook, C Su, ...
Cell 186 (26), 5840-5858. e36, 2023
92023
Methods of editing DNA methylation
R Jaenisch, XS Liu, H Wu
US Patent 11,434,476, 2022
92022
Spatially coordinated heterochromatinization of distal short tandem repeats in fragile X syndrome
L Zhou, C Ge, T Malachowski, JH Kim, KR Chandradoss, C Su, H Wu, ...
bioRxiv, 2021.04. 23.441217, 2021
62021
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