| High-throughput screening assays for the identification of chemical probes J Inglese, RL Johnson, A Simeonov, M Xia, W Zheng, CP Austin, DS Auld Nature chemical biology 3 (8), 466-479, 2007 | 761 | 2007 |
| Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ... Nature medicine 22 (10), 1101-1107, 2016 | 708 | 2016 |
| Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ... ACS chemical biology 11 (11), 3214-3225, 2016 | 485 | 2016 |
| Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 359 | 2015 |
| Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action SC Miller, R Huang, S Sakamuru, SJ Shukla, MS Attene-Ramos, P Shinn, ... Biochemical pharmacology 79 (9), 1272-1280, 2010 | 326 | 2010 |
| The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform SJ Shukla, R Huang, CP Austin, M Xia Drug discovery today 15 (23-24), 997-1007, 2010 | 307 | 2010 |
| Compound cytotoxicity profiling using quantitative high-throughput screening M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ... Environmental health perspectives 116 (3), 284-291, 2008 | 303 | 2008 |
| 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ... Nature structural & molecular biology 19 (10), 1037-1043, 2012 | 299 | 2012 |
| Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ... Toxicological Sciences 148 (1), 137-154, 2015 | 297 | 2015 |
| Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ... Toxicological Sciences 152 (2), 323-339, 2016 | 273 | 2016 |
| Mitochondrial membrane potential assay S Sakamuru, MS Attene-Ramos, M Xia High-throughput screening assays in toxicology, 17-22, 2016 | 264 | 2016 |
| The Tox21 robotic platform for the assessment of environmental chemicals–from vision to reality MS Attene-Ramos, N Miller, R Huang, S Michael, M Itkin, RJ Kavlock, ... Drug discovery today 18 (15-16), 716-723, 2013 | 257 | 2013 |
| Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization R Huang, M Xia, S Sakamuru, J Zhao, SA Shahane, M Attene-Ramos, ... Nature communications 7 (1), 10425, 2016 | 247 | 2016 |
| Bisphenol A affects androgen receptor function via multiple mechanisms C Teng, B Goodwin, K Shockley, M Xia, R Huang, J Norris, BA Merrick, ... Chemico-biological interactions 203 (3), 556-564, 2013 | 226 | 2013 |
| Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ... Environmental science & technology 44 (15), 5979-5985, 2010 | 223 | 2010 |
| Tox21Challenge to build predictive models of nuclear receptor and stress response pathways as mediated by exposure to environmental chemicals and drugs R Huang, M Xia, DT Nguyen, T Zhao, S Sakamuru, J Zhao, SA Shahane, ... Frontiers in Environmental Science 3, 85, 2016 | 219 | 2016 |
| Chemical genomics profiling of environmental chemical modulation of human nuclear receptors R Huang, M Xia, MH Cho, S Sakamuru, P Shinn, KA Houck, DJ Dix, ... Environmental health perspectives 119 (8), 1142-1148, 2011 | 214 | 2011 |
| Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction Z Li, M Brecher, YQ Deng, J Zhang, S Sakamuru, B Liu, R Huang, ... Cell research 27 (8), 1046-1064, 2017 | 209 | 2017 |
| Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane. M Xia, D Leppert, SL Hauser, SP Sreedharan, PJ Nelson, AM Krensky, ... Journal of immunology (Baltimore, Md.: 1950) 156 (1), 160-167, 1996 | 209 | 1996 |
| Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals ATJ Murk, E Rijntjes, BJ Blaauboer, R Clewell, KM Crofton, ... Toxicology in vitro 27 (4), 1320-1346, 2013 | 206 | 2013 |