A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol NM Nesbitt, X Yang, P Fontán, I Kolesnikova, I Smith, NS Sampson, ... Infection and immunity 78 (1), 275-282, 2010 | 274 | 2010 |
Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration K Zarrabi, A Dufour, J Li, C Kuscu, A Pulkoski-Gross, J Zhi, Y Hu, ... Journal of Biological Chemistry 286 (38), 33167-33177, 2011 | 240 | 2011 |
Role of the hemopexin domain of matrix metalloproteinases in cell migration A Dufour, NS Sampson, S Zucker, J Cao Journal of cellular physiology 217 (3), 643-651, 2008 | 191 | 2008 |
Pathogen roid rage: Cholesterol utilization by Mycobacterium tuberculosis MF Wipperman, NS Sampson, ST Thomas Critical reviews in biochemistry and molecular biology 49 (4), 269-293, 2014 | 179 | 2014 |
Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides A Dufour, S Zucker, NS Sampson, C Kuscu, J Cao Journal of Biological Chemistry 285 (46), 35944-35956, 2010 | 175 | 2010 |
Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox … PI Lario, N Sampson, A Vrielink Journal of molecular biology 326 (5), 1635-1650, 2003 | 172 | 2003 |
Crystal Structure Determination of Cholesterol Oxidase from Streptomyces and Structural Characterization of Key Active Site Mutants, QK Yue, IJ Kass, NS Sampson, A Vrielink Biochemistry 38 (14), 4277-4286, 1999 | 171 | 1999 |
Mediation of sperm-egg fusion: evidence that mouse egg α6β1 integrin is the receptor for sperm fertilinβ H Chen, NS Sampson Chemistry & biology 6 (1), 1-10, 1999 | 169 | 1999 |
Segmental motion in catalysis: investigation of a hydrogen bond critical for loop closure in the reaction of triosephosphate isomerase NS Sampson, JR Knowles Biochemistry 31 (36), 8488-8494, 1992 | 169 | 1992 |
Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9 A Dufour, NS Sampson, J Li, C Kuscu, RC Rizzo, JL DeLeon, J Zhi, ... Cancer research 71 (14), 4977-4988, 2011 | 149 | 2011 |
Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase NS Sampson, JR Knowles Biochemistry 31 (36), 8482-8487, 1992 | 146 | 1992 |
Rv1106c from Mycobacterium tuberculosis Is a 3β-Hydroxysteroid Dehydrogenase X Yang, E Dubnau, I Smith, NS Sampson Biochemistry 46 (31), 9058-9067, 2007 | 145 | 2007 |
Cholesterol Metabolism Increases the Metabolic Pool of Propionate in Mycobacterium tuberculosis X Yang, NM Nesbitt, E Dubnau, I Smith, NS Sampson Biochemistry 48 (18), 3819-3821, 2009 | 137 | 2009 |
Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism ST Thomas, BC VanderVen, DR Sherman, DG Russell, NS Sampson Journal of Biological Chemistry 286 (51), 43668-43678, 2011 | 134 | 2011 |
Antibacterial studies of cationic polymers with alternating, random, and uniform backbones A Song, SG Walker, KA Parker, NS Sampson ACS chemical biology 6 (6), 590-599, 2011 | 127 | 2011 |
Synthesis of copolymers by alternating ROMP (AROMP) A Song, KA Parker, NS Sampson Journal of the American Chemical Society 131 (10), 3444-3445, 2009 | 125 | 2009 |
Hit generation in TB drug discovery: from genome to granuloma T Yuan, NS Sampson Chemical reviews 118 (4), 1887-1916, 2018 | 119 | 2018 |
Dynamic requirements for a functional protein hinge JG Kempf, J Jung, C Ragain, NS Sampson, JP Loria Journal of Molecular Biology 368 (1), 131-149, 2007 | 112 | 2007 |
Cholesterol oxidase: physiological functions J Kreit, NS Sampson The FEBS journal 276 (23), 6844-6856, 2009 | 106 | 2009 |
Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease N Ueki, S Lee, NS Sampson, MJ Hayman Nature communications 4 (1), 2735, 2013 | 105 | 2013 |