Articles with public access mandates - Johan Van LintLearn more
Not available anywhere: 2
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours
N Azoitei, GV Pusapati, A Kleger, P Möller, R Küfer, F Genze, M Wagner, ...
Gut 59 (10), 1316-1330, 2010
Mandates: Research Foundation (Flanders), German Research Foundation
Developments in the discovery and design of protein kinase D inhibitors
P Gilles, L Voets, J Van Lint, WM De Borggraeve
ChemMedChem 16 (14), 2158-2171, 2021
Mandates: Research Foundation (Flanders)
Available somewhere: 21
Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin
T Eiseler, A Hausser, L De Kimpe, J Van Lint, K Pfizenmaier
Journal of Biological Chemistry 285 (24), 18672-18683, 2010
Mandates: Research Foundation (Flanders)
Control of MT1-MMP transport by atypical PKC during breast-cancer progression
C Rossé, C Lodillinsky, L Fuhrmann, M Nourieh, P Monteiro, M Irondelle, ...
Proceedings of the National Academy of Sciences 111 (18), E1872-E1879, 2014
Mandates: Australian Research Council, Cancer Research UK
Protein kinase D induces transcription through direct phosphorylation of the cAMP-response element-binding protein
M Johannessen, MP Delghandi, A Rykx, M Dragset, JR Vandenheede, ...
Journal of biological chemistry 282 (20), 14777-14787, 2007
Mandates: Research Foundation (Flanders)
HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization
N Azoitei, K Diepold, C Brunner, A Rouhi, F Genze, A Becher, H Kestler, ...
Cancer research 74 (23), 7125-7136, 2014
Mandates: US National Institutes of Health, German Research Foundation
Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2
J von Blume, U Knippschild, F Dequiedt, G Giamas, A Beck, A Auer, ...
The EMBO journal 26 (22), 4619-4633, 2007
Mandates: Research Foundation (Flanders), German Research Foundation
Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1, 4, 5-trisphosphate receptor
B Devogelaere, M Beullens, E Sammels, R Derua, E Waelkens, J Van Lint, ...
Biochemical Journal 407 (2), 303-311, 2007
Mandates: Research Foundation (Flanders)
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation
N Azoitei, A Kleger, N Schoo, DR Thal, C Brunner, GV Pusapati, ...
Neuro-oncology 13 (7), 710-724, 2011
Mandates: German Research Foundation
Characterization of cortactin as an in vivo protein kinase D substrate: interdependence of sites and potentiation by Src
L De Kimpe, K Janssens, R Derua, M Armacki, S Goicoechea, C Otey, ...
Cellular signalling 21 (2), 253-263, 2009
Mandates: Research Foundation (Flanders)
Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling
D Bauters, M Cobbaut, L Geys, J Van Lint, B Hemmeryckx, HR Lijnen
Molecular metabolism 6 (7), 715-724, 2017
Mandates: US National Institutes of Health
Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation
R Sroka, J Van Lint, SF Katz, MR Schneider, A Kleger, S Paschke, ...
Journal of cell science 129 (12), 2416-2429, 2016
Mandates: Research Foundation (Flanders), German Research Foundation
A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis
M Armacki, G Joodi, SC Nimmagadda, L De Kimpe, GV Pusapati, ...
Oncogene 33 (9), 1167-1180, 2014
Mandates: Research Foundation (Flanders)
Characterization of EVL-I as a protein kinase D substrate
K Janssens, L De Kimpe, M Balsamo, S Vandoninck, JR Vandenheede, ...
Cellular signalling 21 (2), 282-292, 2009
Mandates: US National Institutes of Health, Research Foundation (Flanders)
Protein kinase D2: a versatile player in cancer biology
N Azoitei, M Cobbaut, A Becher, J Van Lint, T Seufferlein
Oncogene 37 (10), 1263-1278, 2018
Mandates: Research Foundation (Flanders), German Research Foundation
Protein kinase D regulates RhoA activity via rhotekin phosphorylation
GV Pusapati, T Eiseler, A Rykx, S Vandoninck, R Derua, E Waelkens, ...
Journal of Biological Chemistry 287 (12), 9473-9483, 2012
Mandates: Research Foundation (Flanders)
Protein kinase D increases maximal Ca2+-activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser315
E Dirkx, O Cazorla, RW Schwenk, I Lorenzen-Schmidt, S Sadayappan, ...
American Journal of Physiology-Heart and Circulatory Physiology 303 (3 …, 2012
Mandates: US National Institutes of Health
Design, synthesis and biological evaluation of pyrazolo [3, 4-d] pyrimidine-based protein kinase D inhibitors
P Gilles, RS Kashyap, MJ Freitas, S Ceusters, K Van Asch, A Janssens, ...
European Journal of Medicinal Chemistry 205, 112638, 2020
Mandates: Research Foundation (Flanders)
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+ 1 loop
M Cobbaut, R Derua, H Döppler, HJ Lou, S Vandoninck, P Storz, BE Turk, ...
Scientific reports 7 (1), 887, 2017
Mandates: US National Institutes of Health, Research Foundation (Flanders)
Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo [3, 4-d] pyrimidine analogues
K Verschueren, M Cobbaut, J Demaerel, L Saadah, ARD Voet, J Van Lint, ...
MedChemComm 8 (3), 640-646, 2017
Mandates: Research Foundation (Flanders)
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