| Bypass of Senescence After Disruption of p21CIP1/WAF1 Gene in Normal Diploid Human Fibroblasts JP Brown, W Wei, JM Sedivy Science 277 (5327), 831-834, 1997 | 1103 | 1997 |
| Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance J Zhang, X Bu, H Wang, Y Zhu, Y Geng, NT Nihira, Y Tan, Y Ci, F Wu, ... Nature 553 (7686), 91-95, 2018 | 913 | 2018 |
| Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization CM Counter, WC Hahn, W Wei, SD Caddle, RL Beijersbergen, ... Proceedings of the National Academy of Sciences 95 (25), 14723-14728, 1998 | 836 | 1998 |
| SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction H Inuzuka, S Shaik, I Onoyama, D Gao, A Tseng, RS Maser, B Zhai, ... Nature 471 (7336), 104-109, 2011 | 720 | 2011 |
| Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer S Lee, E Nakamura, H Yang, W Wei, MS Linggi, MP Sajan, RV Farese, ... Cancer cell 8 (2), 155-167, 2005 | 646 | 2005 |
| Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex W Wei, NG Ayad, Y Wan, GJ Zhang, MW Kirschner, WG Kaelin Jr Nature 428 (6979), 194-198, 2004 | 581 | 2004 |
| The role of ubiquitination in tumorigenesis and targeted drug discovery L Deng, T Meng, L Chen, W Wei, P Wang Signal transduction and targeted therapy 5 (1), 11, 2020 | 568 | 2020 |
| Roles of F-box proteins in cancer Z Wang, P Liu, H Inuzuka, W Wei Nature reviews Cancer 14 (4), 233-247, 2014 | 526 | 2014 |
| The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase W Wei, J Jin, S Schlisio, JW Harper, WG Kaelin Cancer cell 8 (1), 25-33, 2005 | 498 | 2005 |
| PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ... Cancer discovery 5 (11), 1194-1209, 2015 | 457 | 2015 |
| The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis CH Chan, CF Li, WL Yang, Y Gao, SW Lee, Z Feng, HY Huang, KKC Tsai, ... Cell 149 (5), 1098-1111, 2012 | 445 | 2012 |
| Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus P Liu, M Begley, W Michowski, H Inuzuka, M Ginzberg, D Gao, P Tsou, ... Nature 508 (7497), 541-545, 2014 | 402 | 2014 |
| Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin Z Han, W Wei, S Dunaway, JW Darnowski, P Calabresi, J Sedivy, ... Journal of Biological Chemistry 277 (19), 17154-17160, 2002 | 328 | 2002 |
| Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ... Cell 157 (3), 595-610, 2014 | 321 | 2014 |
| Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4 X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ... Nature medicine 23 (9), 1063-1071, 2017 | 311 | 2017 |
| Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis P Liu, W Gan, H Inuzuka, AS Lazorchak, D Gao, O Arojo, D Liu, L Wan, ... Nature cell biology 15 (11), 1340-1350, 2013 | 307 | 2013 |
| Light-induced control of protein destruction by opto-PROTAC J Liu, H Chen, L Ma, Z He, D Wang, Y Liu, Q Lin, T Zhang, N Gray, ... Science advances 6 (8), eaay5154, 2020 | 296 | 2020 |
| Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ... Nature cell biology 22 (9), 1064-1075, 2020 | 292 | 2020 |
| Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction D Gao, H Inuzuka, A Tseng, RY Chin, A Toker, W Wei Nature cell biology 11 (4), 397-408, 2009 | 292 | 2009 |
| Role of p14ARF in Replicative and Induced Senescence of Human Fibroblasts W Wei, RM Hemmer, JM Sedivy Molecular and cellular biology 21 (20), 6748-6757, 2001 | 289 | 2001 |
