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George Lisi
George Lisi
Verified email at brown.edu
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Cited by
Cited by
Year
Eigenvector centrality for characterization of protein allosteric pathways
CFA Negre, UN Morzan, HP Hendrickson, R Pal, GP Lisi, JP Loria, ...
Proceedings of the National Academy of Sciences 115 (52), E12201-E12208, 2018
2242018
Solution NMR spectroscopy for the study of enzyme allostery
GP Lisi, JP Loria
Chemical reviews 116 (11), 6323-6369, 2016
1292016
Allosteric motions of the CRISPR–Cas9 HNH nuclease probed by NMR and molecular dynamics
KW East, JC Newton, UN Morzan, YB Narkhede, A Acharya, E Skeens, ...
Journal of the American Chemical Society 142 (3), 1348-1358, 2019
952019
Allostery in enzyme catalysis
GP Lisi, JP Loria
Current Opinion in Structural Biology 47, 123-130, 2017
702017
A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch
JF Amacher, F Zhong, GP Lisi, MQ Zhu, SL Alden, KR Hoke, DR Madden, ...
Journal of the American Chemical Society 137 (26), 8435-8449, 2015
632015
Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity
GP Lisi, KW East, VS Batista, JP Loria
Proceedings of the National Academy of Sciences 114 (17), E3414-E3423, 2017
612017
Using NMR spectroscopy to elucidate the role of molecular motions in enzyme function
GP Lisi, JP Loria
Progress in nuclear magnetic resonance spectroscopy 92, 1-17, 2016
582016
Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins
F Zhong, GP Lisi, DP Collins, JH Dawson, EV Pletneva
Proceedings of the National Academy of Sciences 111 (3), E306-E315, 2014
562014
Novel biomarkers of hepatitis B virus and their use in chronic hepatitis B patient management
A Vachon, C Osiowy
Viruses 13 (6), 951, 2021
502021
Allosteric communication disrupted by a small molecule binding to the imidazole glycerol phosphate synthase protein–protein interface
I Rivalta, GP Lisi, NS Snoeberger, G Manley, JP Loria, VS Batista
Biochemistry 55 (47), 6484-6494, 2016
452016
Dissecting dynamic allosteric pathways using chemically related small-molecule activators
GP Lisi, GA Manley, H Hendrickson, I Rivalta, VS Batista, JP Loria
Structure 24 (7), 1155-1166, 2016
452016
NMR and computational methods for molecular resolution of allosteric pathways in enzyme complexes
KW East, E Skeens, JY Cui, HB Belato, B Mitchell, R Hsu, VS Batista, ...
Biophysical reviews 12 (1), 155-174, 2020
442020
Syntheses, characterization, density functional theory calculations, and activity of tridentate SNS zinc pincer complexes based on bis-imidazole or bis-triazole precursors
JR Miecznikowski, W Lo, MA Lynn, S Jain, LC Keilich, NF Kloczko, ...
Inorganica Chimica Acta 387, 25-36, 2012
412012
Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9
L Nierzwicki, KW East, UN Morzan, PR Arantes, VS Batista, GP Lisi, ...
Elife 10, e73601, 2021
372021
Thermodynamic contributions to the stability of the insulin hexamer
GP Lisi, CYM Png, DE Wilcox
Biochemistry 53 (22), 3576-3584, 2014
342014
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2
G Monteiro da Silva, JY Cui, DC Dalgarno, GP Lisi, BM Rubenstein
nature communications 15 (1), 2464, 2024
332024
Glutamine hydrolysis by imidazole glycerol phosphate synthase displays temperature dependent allosteric activation
GP Lisi, AA Currier, JP Loria
Frontiers in Molecular Biosciences 5, 4, 2018
332018
Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9
Ł Nierzwicki, KW East, JM Binz, RV Hsu, M Ahsan, PR Arantes, E Skeens, ...
Nature catalysis 5 (10), 912-922, 2022
302022
Regulation of MIF enzymatic activity by an allosteric site at the central solvent channel
G Pantouris, L Khurana, A Ma, E Skeens, K Reiss, VS Batista, GP Lisi, ...
Cell chemical biology 27 (6), 740-750. e5, 2020
302020
Syntheses, characterization, density functional theory calculations, and activity of tridentate SNS zinc pincer complexes
JR Miecznikowski, W Lo, MA Lynn, BE O’Loughlin, AP DiMarzio, ...
Inorganica Chimica Acta 376 (1), 515-524, 2011
302011
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