Gina Sanchez

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Paulina DonosoInstituto de Ciencias Biomedicas. Facultad de Medicina. Universidad de ChileVerified email at med.uchile.cl
Cecilia HidalgoDept. Neurosciences, BNI, CEMC, ICBM, F. Medicine, Universidad de ChileVerified email at med.uchile.cl
Zully PedrozoUniversidad de ChileVerified email at med.uchile.cl
Sergio LavanderoPremio Nacional Cs Naturales 2022, Profesor-Senador U Chile, Director ACDDiS, Adjunct Prof, UTSWVerified email at uchile.cl
Jaime A RiquelmeAssistant Professor, Facultad de Ciencias de Ciencias Químicas y Farmacéuticas, Universidad de ChileVerified email at ciq.uchile.cl
Genaro Christian BarrientosProfesor AisitenteVerified email at uchile.cl
Ricardo BullDept. Physiology & Biophysics, ICBM, Faculty of Medicine, University of ChileVerified email at med.uchile.cl
Mario ChiongAdvanced Center For Chronic Diseases. Departamento de Bioquímica y Biología Molecular. Facultad deVerified email at ciq.uchile.cl
María Matilde SaidProfesor Adjunto ordinario, Investigador Adjunto CONICET, Facultad de Ciencias Médicas, UniversidadVerified email at aetos.med.unlp.edu.ar
Pablo Muñoz CarvajalProfesor titular, Departamento Fisiología y Patología, Escuela de Medicina, Facultad de MedicinaVerified email at uv.cl
Jose L ValdesAssociated Professor, Departement of Neurociencias, University of ChileVerified email at uchile.cl
Alicia MattiazziProfessorVerified email at med.unlp.edu.ar
Leticia VittoneFacultad de Ciencias Médicas, UNLP, Cátedra de FisiologíaVerified email at med.unlp.edu.ar
Tatiana Adasme RochaHospital Clínico Universidad de Chile (HCUCH)Verified email at ciq.uchile.cl
Cecilia MundinaProfesor Fisiología y Física Biológica, Universidad Nacional de La PlataVerified email at med.unlp.edu.ar
Valentina ParraACCDiS, Advanced Center for Chronic Diseases. Universidad de Chile.Verified email at ciq.uchile.cl
Carlos A. ValverdeProfesor Adjunto de Fisiología y Física Biológica Universidad Nacional de La Plata - Centro deVerified email at med.unlp.edu.ar
Rodrigo TroncosoIntituto de Nutrición y Tecnología de los AlimentosVerified email at inta.uchile.cl
Francisco WestermeierFH Joanneum / Graz, AustriaVerified email at fh-joanneum.at
Maria Isabel Ofelia BehrensProfesor Titular Neurologia Hospital Clinico Universidad de ChileVerified email at uchile.cl

Gina Sanchez

Facultad de Medicina Universidad de Chile

Verified email at med.uchile.cl

Cardiovascular Modificaciones Redox Mitocondrias


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A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S-glutathionylation C Hidalgo, G Sánchez, G Barrientos, P Aracena-Parks Journal of Biological Chemistry 281 (36), 26473-26482, 2006	214	2006
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart M Ibacache, G Sanchez, Z Pedrozo, F Galvez, C Humeres, G Echevarria, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (4), 537-545, 2012	186	2012
Exercise induces early and late myocardial preconditioning in dogs R Domenech, P Macho, H Schwarze, G Sánchez Cardiovascular research 55 (3), 561-566, 2002	174	2002
The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury MA Salas, CA Valverde, G Sánchez, M Said, JS Rodriguez, EL Portiansky, ... Journal of molecular and cellular cardiology 48 (6), 1298-1306, 2010	154	2010
S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels P Aracena, G Sánchez, P Donoso, SL Hamilton, C Hidalgo Journal of Biological Chemistry 278 (44), 42927-42935, 2003	148	2003
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle G Sánchez, Z Pedrozo, RJ Domenech, C Hidalgo, P Donoso Journal of molecular and cellular cardiology 39 (6), 982-991, 2005	143	2005
Modulation of cardiac ryanodine receptor activity by ROS and RNS P Donoso, G Sanchez, R Bull, C Hidalgo Front Biosci 16, 553-567, 2011	137	2011
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection G Sánchez, M Escobar, Z Pedrozo, P Macho, R Domenech, S Härtel, ... Cardiovascular research 77 (2), 380-386, 2008	136	2008
Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex R Bull, JP Finkelstein, J Gálvez, G Sánchez, P Donoso, MI Behrens, ... Journal of Neuroscience 28 (38), 9463-9472, 2008	113	2008
Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury R Zepeda, J Kuzmicic, V Parra, R Troncoso, C Pennanen, JA Riquelme, ... Journal of cardiovascular pharmacology 63 (6), 477-487, 2014	112	2014
Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism JA Riquelme, F Westermeier, AR Hall, JM Vicencio, Z Pedrozo, ... Pharmacological research 103, 318-327, 2016	111	2016
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during β-adrenergic stimulation P Ferrero, M Said, G Sánchez, L Vittone, C Valverde, P Donoso, ... Journal of molecular and cellular cardiology 43 (3), 281-291, 2007	105	2007
Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons U Kemmerling, P Muñoz, M Müller, G Sánchez, ML Aylwin, E Klann, ... Cell calcium 41 (5), 491-502, 2007	105	2007
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion Z Pedrozo, G Sánchez, N Torrealba, R Valenzuela, C Fernández, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (3), 356-362, 2010	98	2010
Tachycardia preconditions infarct size in dogs: role of adenosine and protein kinase C RJ Domenech, P Macho, D Vélez, G Sánchez, X Liu, N Dhalla Circulation 97 (8), 786-794, 1998	95	1998
Aging impairs hippocampal-dependent recognition memory and LTP and prevents the associated RyR up-regulation A Arias-Cavieres, T Adasme, G Sánchez, P Muñoz, C Hidalgo Frontiers in aging neuroscience 9, 111, 2017	73	2017
N-acetylcysteine prevents the spatial memory deficits and the redox-dependent RyR2 decrease displayed by an Alzheimer’s disease rat model J More, N Galusso, P Veloso, L Montecinos, JP Finkelstein, G Sanchez, ... Frontiers in aging neuroscience 10, 399, 2018	62	2018
Las MIPYMES en el contexto mundial: sus particularidades en méxico. Iberóforum J Valdés, G Sánchez Revista de Ciencias Sociales de la Universidad Iberoamericana 7 (14), 126-156, 2012	62	2012
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy Z Pedrozo, N Torrealba, C Fernández, D Gatica, B Toro, C Quiroga, ... Cardiovascular research 98 (2), 277-285, 2013	60	2013
Redox regulation of calcium release in skeletal and cardiac muscle C Hidalgo, P Aracena, G Sanchez, P Donoso Biological research 35 (2), 183-193, 2002	58	2002

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