| Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer I Tekedereli, SN Alpay, CDJ Tavares, ZE Cobanoglu, TS Kaoud, I Sahin, ... PloS one 7 (7), e41171, 2012 | 144 | 2012 |
| c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun X Xie, TS Kaoud, R Edupuganti, T Zhang, T Kogawa, Y Zhao, ... Oncogene 36 (18), 2599-2608, 2017 | 101 | 2017 |
| 193‐nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization JA Madsen, TS Kaoud, KN Dalby, JS Brodbelt Proteomics 11 (7), 1329-1334, 2011 | 95 | 2011 |
| Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence CDJ Tavares, JP O’Brien, O Abramczyk, AK Devkota, KS Shores, ... Biochemistry 51 (11), 2232-2245, 2012 | 75 | 2012 |
| Nonvisual arrestins function as simple scaffolds assembling the MKK4–JNK3α2 signaling complex X Zhan, TS Kaoud, KN Dalby, VV Gurevich Biochemistry 50 (48), 10520-10529, 2011 | 73 | 2011 |
| In-situ generation of differential sensors that fingerprint kinases and the cellular response to their expression D Zamora-Olivares, TS Kaoud, KN Dalby, EV Anslyn Journal of the American Chemical Society 135 (39), 14814-14820, 2013 | 72 | 2013 |
| Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding S Kook, X Zhan, TS Kaoud, KN Dalby, VV Gurevich, EV Gurevich Journal of Biological Chemistry 288 (52), 37332-37342, 2013 | 70 | 2013 |
| JNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinases X Zhan, TS Kaoud, S Kook, KN Dalby, VV Gurevich Journal of Biological Chemistry 288 (40), 28535-28547, 2013 | 67 | 2013 |
| Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact AK Devkota, CDJ Tavares, M Warthaka, O Abramczyk, KD Marshall, ... Biochemistry 51 (10), 2100-2112, 2012 | 67 | 2012 |
| Peptide mini-scaffold facilitates JNK3 activation in cells X Zhan, H Stoy, TS Kaoud, NA Perry, Q Chen, A Perez, S Els-Heindl, ... Scientific Reports 6 (1), 21025, 2016 | 63 | 2016 |
| New 1, 3, 4-oxadiazole/oxime hybrids: Design, synthesis, anti-inflammatory, COX inhibitory activities and ulcerogenic liability HS Abd-Ellah, M Abdel-Aziz, ME Shoman, EAM Beshr, TS Kaoud, ... Bioorganic Chemistry 74, 15-29, 2017 | 60 | 2017 |
| Novel quinoline incorporating 1, 2, 4-triazole/oxime hybrids: synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations AM Mohassab, HA Hassan, D Abdelhamid, M Abdel-Aziz, KN Dalby, ... Bioorganic chemistry 75, 242-259, 2017 | 58 | 2017 |
| Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration TS Kaoud, S Mitra, S Lee, J Taliaferro, M Cantrell, KD Linse, ... ACS chemical biology 6 (6), 658-666, 2011 | 57 | 2011 |
| Novel 1-[4-(Aminosulfonyl) phenyl]-1H-1, 2, 4-triazole derivatives with remarkable selective COX-2 inhibition: Design, synthesis, molecular docking, anti-inflammatory and … GEDAA Abuo-Rahma, M Abdel-Aziz, NA Farag, TS Kaoud European journal of medicinal chemistry 83, 398-408, 2014 | 54 | 2014 |
| Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding HF Guo, CL Tsai, M Terajima, X Tan, P Banerjee, MD Miller, X Liu, J Yu, ... Nature communications 9 (1), 512, 2018 | 52 | 2018 |
| Novel 1, 3, 4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities HS Abd-Ellah, M Abdel-Aziz, ME Shoman, EAM Beshr, TS Kaoud, ... Bioorganic Chemistry 69, 48-63, 2016 | 52 | 2016 |
| Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15 TS Kaoud, AK Devkota, R Harris, MS Rana, O Abramczyk, M Warthaka, ... Biochemistry 50 (21), 4568-4578, 2011 | 51 | 2011 |
| Design, synthesis and biological evaluation of fused naphthofuro [3, 2-c] quinoline-6, 7, 12-triones and pyrano [3, 2-c] quinoline-6, 7, 8, 13-tetraones derivatives as ERK … AA Aly, EM El-Sheref, MEM Bakheet, MAE Mourad, S Bräse, MAA Ibrahim, ... Bioorganic chemistry 82, 290-305, 2019 | 50 | 2019 |
| Solution NMR insights into docking interactions involving inactive ERK2 A Piserchio, M Warthaka, AK Devkota, TS Kaoud, S Lee, O Abramczyk, ... Biochemistry 50 (18), 3660-3672, 2011 | 50 | 2011 |
| Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification NA Perry, TS Kaoud, OO Ortega, AI Kaya, DJ Marcus, JM Pleinis, S Berndt, ... Proceedings of the National Academy of Sciences 116 (3), 810-815, 2019 | 49 | 2019 |
Kevin Dalby, UT AustinProfessor of Chemical Biology, The University of Texas at AustinVerified email at austin.utexas.edu