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Wenchun Chen
Wenchun Chen
Verified email at emory.edu
Title
Cited by
Cited by
Year
Mechanisms of platelet clearance and translation to improve platelet storage
ME Quach, W Chen, R Li
Blood, The Journal of the American Society of Hematology 131 (14), 1512-1521, 2018
2502018
Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor
W Deng, Y Xu, W Chen, DS Paul, AK Syed, MA Dragovich, X Liang, ...
Nature communications 7 (1), 12863, 2016
1132016
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage
ZW Sun, L Zhang, SJ Zhu, WC Chen, B Mei
Neuroscience bulletin 26 (1), 8, 2010
1062010
Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets
ME Quach, MA Dragovich, W Chen, AK Syed, W Cao, X Liang, W Deng, ...
Blood, The Journal of the American Society of Hematology 131 (7), 787-796, 2018
942018
Inhibiting GPIbα shedding preserves post-transfusion recovery and hemostatic function of platelets after prolonged storage
W Chen, X Liang, AK Syed, P Jessup, WR Church, J Ware, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (9), 1821-1828, 2016
672016
TRPM7 kinase controls calcium responses in arterial thrombosis and stroke in mice
SK Gotru, W Chen, P Kraft, IC Becker, K Wolf, S Stritt, S Zierler, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (2), 344-352, 2018
652018
Refrigeration-induced binding of von Willebrand factor facilitates fast clearance of refrigerated platelets
W Chen, SA Druzak, Y Wang, CD Josephson, KM Hoffmeister, J Ware, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (12), 2271-2279, 2017
582017
Orai1‐induced store‐operated Calcium entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets
W Chen, I Thielmann, S Gupta, H Subramanian, D Stegner, R Kruchten, ...
Journal of Thrombosis and Haemostasis 12 (4), 528-539, 2014
422014
Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance
Y Wang, W Chen, W Zhang, MM Lee-Sundlov, C Casari, MC Berndt, ...
Haematologica 106 (1), 220, 2021
352021
Partially defective store operated calcium entry and hem (ITAM) signaling in platelets of serotonin transporter deficient mice
K Wolf, A Braun, EJ Haining, YL Tseng, P Kraft, MK Schuhmann, SK Gotru, ...
PLoS One 11 (1), e0147664, 2016
342016
Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction
Y Qi, W Chen, X Liang, K Xu, X Gu, F Wu, X Fan, S Ren, J Liu, J Zhang, ...
Journal of Hematology & Oncology 11, 1-17, 2018
322018
DNA‐based microparticle tension sensors (μTS) for measuring cell mechanics in non‐planar geometries and for high‐throughput quantification
Y Hu, VPY Ma, R Ma, W Chen, Y Duan, R Glazier, BG Petrich, R Li, ...
Angewandte Chemie 133 (33), 18192-18198, 2021
192021
Short-acting anti-VWF (von Willebrand Factor) aptamer improves the recovery, survival, and hemostatic functions of refrigerated platelets
W Chen, KM Voos, CD Josephson, R Li
Arteriosclerosis, thrombosis, and vascular biology 39 (10), 2028-2037, 2019
162019
Differential regulation of the platelet GPIb‐IX complex by anti‐GPIbβ antibodies
ME Quach, W Chen, Y Wang, H Deckmyn, F Lanza, B Nieswandt, R Li
Journal of Thrombosis and Haemostasis 19 (8), 2044-2055, 2021
112021
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
A Blanchard, JD Combs, JM Brockman, AV Kellner, R Glazier, H Su, ...
Nature Communications 12 (1), 4693, 2021
82021
Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand
Y Duan, F Szlam, Y Hu, W Chen, R Li, Y Ke, R Sniecinski, K Salaita
Nature Biomedical Engineering 7 (11), 1404-1418, 2023
62023
Molecular mechanocytometry using tension-activated cell tagging
R Ma, SA Rashid, A Velusamy, BR Deal, W Chen, B Petrich, R Li, ...
Nature Methods 20 (11), 1666-1671, 2023
62023
Fast clearance of platelets in a commonly used mouse model for GPIbα is impeded by an anti‐GPIbβ antibody derivative
W Chen, MS Wilson, Y Wang, W Bergmeier, F Lanza, R Li
Journal of Thrombosis and Haemostasis 20 (6), 1451-1463, 2022
32022
Micromolar concentrations of citalopram or escitalopram inhibit glycoprotein VI-mediated and integrin αIIbβ3-mediated signaling in human platelets
YL Tseng, A Braun, JPC Chang, ML Chiang, CY Tseng, W Chen
Toxicology and Applied Pharmacology 364, 106-113, 2019
32019
Autoinhibitory module underlies species difference in shear activation of von Willebrand factor
NA Arce, Y Liu, W Chen, XF Zhang, R Li
Journal of Thrombosis and Haemostasis 20 (11), 2686-2696, 2022
12022
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