| Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 251 | 2020 |
| Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus SB Baver, K Hope, S Guyot, C Bjørbaek, C Kaczorowski, KMS O'Connell Journal of Neuroscience 34 (16), 5486-5496, 2014 | 232 | 2014 |
| Harnessing genetic complexity to enhance translatability of Alzheimer’s disease mouse models: a path toward precision medicine SM Neuner, SE Heuer, MJ Huentelman, KMS O’Connell, CC Kaczorowski Neuron 101 (3), 399-411. e5, 2019 | 204 | 2019 |
| Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease AR Dunn, KMS O’Connell, CC Kaczorowski Neuroscience & Biobehavioral Reviews 103, 73-80, 2019 | 154 | 2019 |
| Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice CC Kaczorowski, JF Disterhoft Learning & memory 16 (6), 362-366, 2009 | 128 | 2009 |
| Genetic variants and functional pathways associated with resilience to Alzheimer’s disease L Dumitrescu, ER Mahoney, S Mukherjee, ML Lee, WS Bush, ... Brain 143 (8), 2561-2575, 2020 | 123 | 2020 |
| Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease CC Kaczorowski, E Sametsky, S Shah, R Vassar, JF Disterhoft Neurobiology of aging 32 (8), 1452-1465, 2011 | 111 | 2011 |
| An updated unified pharmacophore model of the benzodiazepine binding site on γ-aminobutyric acida receptors: correlation with comparative models T Clayton, JL Chen, M Ernst, L Richter, BA Cromer, CJ Morton, H Ng, ... Current medicinal chemistry 14 (26), 2755-2775, 2007 | 103 | 2007 |
| Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer’s disease mouse models SM Neuner, LA Wilmott, BR Hoffmann, K Mozhui, CC Kaczorowski Behavioural brain research 322, 288-298, 2017 | 98 | 2017 |
| Stability and plasticity of intrinsic membrane properties in hippocampal CA1 pyramidal neurons: effects of internal anions CC Kaczorowski, J Disterhoft, N Spruston The Journal of physiology 578 (3), 799-818, 2007 | 88 | 2007 |
| Rapamycin rejuvenates oral health in aging mice JY An, KA Kerns, A Ouellette, L Robinson, HD Morris, C Kaczorowski, ... Elife 9, e54318, 2020 | 79 | 2020 |
| TRPC3 channels critically regulate hippocampal excitability and contextual fear memory SM Neuner, LA Wilmott, KA Hope, B Hoffmann, JA Chong, J Abramowitz, ... Behavioural brain research 281, 69-77, 2015 | 75 | 2015 |
| A review of the updated pharmacophore for the alpha 5 GABA (A) benzodiazepine receptor model T Clayton, MM Poe, S Rallapalli, P Biawat, MM Savić, JK Rowlett, ... International journal of medicinal chemistry 2015 (1), 430248, 2015 | 71 | 2015 |
| Identification of a Functional Non-coding Variant in the GABAA Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for … MK Mulligan, T Abreo, SM Neuner, C Parks, CE Watkins, MT Houseal, ... Frontiers in genetics 10, 188, 2019 | 63 | 2019 |
| Aging redistributes medial prefrontal neuronal excitability and impedes extinction of trace fear conditioning CC Kaczorowski, SJ Davis, JR Moyer Jr Neurobiology of aging 33 (8), 1744-1757, 2012 | 63 | 2012 |
| Cognitive reserve in model systems for mechanistic discovery: the importance of longitudinal studies JA McQuail, AR Dunn, Y Stern, CA Barnes, G Kempermann, PR Rapp, ... Frontiers in aging neuroscience 12, 607685, 2021 | 60 | 2021 |
| Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice W Wei, K Pham, JW Gammons, D Sutherland, Y Liu, A Smith, ... Scientific reports 5 (1), 16810, 2015 | 58 | 2015 |
| Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease JM Eissman, L Dumitrescu, ER Mahoney, AN Smith, S Mukherjee, ML Lee, ... Brain 145 (7), 2541-2554, 2022 | 57 | 2022 |
| Regulation of intrinsic excitability: Roles for learning and memory, aging and Alzheimer’s disease, and genetic diversity AR Dunn, CC Kaczorowski Neurobiology of Learning and Memory 164, 107069, 2019 | 56 | 2019 |
| Translational approaches to understanding resilience to Alzheimer’s disease SM Neuner, M Telpoukhovskaia, V Menon, KMS O’Connell, TJ Hohman, ... Trends in neurosciences 45 (5), 369-383, 2022 | 48 | 2022 |
Kristen O'ConnellAssociate Professor, The Jackson LaboratoryVerified email at jax.org
