| The development of microgels/nanogels for drug delivery applications JK Oh, R Drumright, DJ Siegwart, K Matyjaszewski Progress in polymer science 33 (4), 448-477, 2008 | 1887 | 2008 |
| Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing Q Cheng, T Wei, L Farbiak, LT Johnson, SA Dilliard, DJ Siegwart Nature nanotechnology 15 (4), 313-320, 2020 | 1377 | 2020 |
| ATRP in the design of functional materials for biomedical applications DJ Siegwart, JK Oh, K Matyjaszewski Progress in polymer science 37 (1), 18-37, 2012 | 692 | 2012 |
| Non‐viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co‐delivery of Cas9 mRNA and sgRNA JB Miller, S Zhang, P Kos, H Xiong, K Zhou, SS Perelman, H Zhu, ... Angewandte Chemie 129 (4), 1079-1083, 2017 | 588 | 2017 |
| Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ... Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014 | 532 | 2014 |
| Biodegradable nanogels prepared by atom transfer radical polymerization as potential drug delivery carriers: synthesis, biodegradation, in vitro release, and bioconjugation JK Oh, DJ Siegwart, H Lee, G Sherwood, L Peteanu, JO Hollinger, ... Journal of the American Chemical Society 129 (18), 5939-5945, 2007 | 523 | 2007 |
| Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing T Wei, Q Cheng, YL Min, EN Olson, DJ Siegwart Nature communications 11 (1), 1-12, 2020 | 492 | 2020 |
| On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles SA Dilliard, Q Cheng, DJ Siegwart Proceedings of the national academy of sciences 118 (52), e2109256118, 2021 | 488 | 2021 |
| Strategies, design, and chemistry in siRNA delivery systems Y Dong, DJ Siegwart, DG Anderson Advanced drug delivery reviews 144, 133-147, 2019 | 471 | 2019 |
| Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart Nature materials 20 (5), 701-710, 2021 | 399 | 2021 |
| Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis P Chen, H Zuo, H Xiong, MJ Kolar, Q Chu, A Saghatelian, DJ Siegwart, ... Proceedings of the National Academy of Sciences 114 (3), 580-585, 2017 | 380 | 2017 |
| Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ... Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011 | 274 | 2011 |
| Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs SA Dilliard, DJ Siegwart Nature Reviews Materials 8 (4), 282-300, 2023 | 217 | 2023 |
| Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery X Wang, S Liu, Y Sun, X Yu, SM Lee, Q Cheng, T Wei, J Gong, ... Nature protocols 18 (1), 265-291, 2023 | 199 | 2023 |
| Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ... Advanced materials 30 (52), 1805308, 2018 | 195 | 2018 |
| An injectable thiol-acrylate poly (ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate CD Pritchard, TM O’Shea, DJ Siegwart, E Calo, DG Anderson, ... Biomaterials 32 (2), 587-597, 2011 | 188 | 2011 |
| Polystyrene with designed molecular weight distribution by atom transfer radical coupling T Sarbu, KY Lin, J Ell, DJ Siegwart, J Spanswick, K Matyjaszewski Macromolecules 37 (9), 3120-3127, 2004 | 187 | 2004 |
| The polyploid state plays a tumor-suppressive role in the liver S Zhang, K Zhou, X Luo, L Li, HC Tu, A Sehgal, LH Nguyen, Y Zhang, ... Developmental cell 44 (4), 447-459. e5, 2018 | 185 | 2018 |
| Synthesis and biodegradation of nanogels as delivery carriers for carbohydrate drugs JK Oh, DJ Siegwart, K Matyjaszewski Biomacromolecules 8 (11), 3326-3331, 2007 | 178 | 2007 |
| Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization SA Bencherif, DJ Siegwart, A Srinivasan, F Horkay, JO Hollinger, ... Biomaterials 30 (29), 5270-5278, 2009 | 173 | 2009 |
Krzysztof MatyjaszewskiCarnegie Mellon UniversityVerified email at andrew.cmu.edu