Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture AM Paşca, SA Sloan, LE Clarke, Y Tian, CD Makinson, N Huber, CH Kim, ... Nature methods 12 (7), 671-678, 2015 | 1492 | 2015 |
Assembly of functionally integrated human forebrain spheroids F Birey, J Andersen, CD Makinson, S Islam, W Wei, N Huber, HC Fan, ... Nature 545 (7652), 54-59, 2017 | 1177 | 2017 |
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain BE Deverman, PL Pravdo, BP Simpson, SR Kumar, KY Chan, A Banerjee, ... Nature biotechnology 34 (2), 204-209, 2016 | 1042 | 2016 |
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome SP Paşca, T Portmann, I Voineagu, M Yazawa, A Shcheglovitov, ... Nature medicine 17 (12), 1657-1662, 2011 | 643 | 2011 |
Human astrocyte maturation captured in 3D cerebral cortical spheroids derived from pluripotent stem cells SA Sloan, S Darmanis, N Huber, TA Khan, F Birey, C Caneda, R Reimer, ... Neuron 95 (4), 779-790. e6, 2017 | 541 | 2017 |
The rise of three-dimensional human brain cultures SP Pașca Nature 553 (7689), 437-445, 2018 | 504 | 2018 |
Reliability of human cortical organoid generation SJ Yoon, LS Elahi, AM Pașca, RM Marton, A Gordon, O Revah, Y Miura, ... Nature methods 16 (1), 75-78, 2019 | 399 | 2019 |
Generation of functional human 3D cortico-motor assembloids J Andersen, O Revah, Y Miura, N Thom, ND Amin, KW Kelley, M Singh, ... Cell 183 (7), 1913-1929. e26, 2020 | 397 | 2020 |
Generation and assembly of human brain region–specific three-dimensional cultures SA Sloan, J Andersen, AM Pașca, F Birey, SP Pașca Nature protocols 13 (9), 2062-2085, 2018 | 382 | 2018 |
Engineered materials for organoid systems MJ Kratochvil, AJ Seymour, TL Li, SP Paşca, CJ Kuo, SC Heilshorn Nature Reviews Materials 4 (9), 606-622, 2019 | 347 | 2019 |
Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures RM Marton, Y Miura, SA Sloan, Q Li, O Revah, RJ Levy, JR Huguenard, ... Nature neuroscience 22 (3), 484-491, 2019 | 310 | 2019 |
Building models of brain disorders with three-dimensional organoids ND Amin, SP Paşca Neuron 100 (2), 389-405, 2018 | 301 | 2018 |
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution AE Trevino, F Müller, J Andersen, L Sundaram, A Kathiria, A Shcherbina, ... Cell 184 (19), 5053-5069. e23, 2021 | 295 | 2021 |
Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells Y Miura, MY Li, F Birey, K Ikeda, O Revah, MV Thete, JY Park, A Puno, ... Nature Biotechnology 38 (12), 1421-1430, 2020 | 289 | 2020 |
Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons JF Krey, SP Paşca, A Shcheglovitov, M Yazawa, R Schwemberger, ... Nature neuroscience 16 (2), 201-209, 2013 | 276 | 2013 |
Maturation and circuit integration of transplanted human cortical organoids O Revah, F Gore, KW Kelley, J Andersen, N Sakai, X Chen, MY Li, F Birey, ... Nature 610 (7931), 319-326, 2022 | 273 | 2022 |
Long-term maturation of human cortical organoids matches key early postnatal transitions A Gordon, SJ Yoon, SS Tran, CD Makinson, JY Park, J Andersen, ... Nature neuroscience 24 (3), 331-342, 2021 | 273 | 2021 |
A tissue-like neurotransmitter sensor for the brain and gut J Li, Y Liu, L Yuan, B Zhang, ES Bishop, K Wang, J Tang, YQ Zheng, ... Nature 606 (7912), 94-101, 2022 | 251 | 2022 |
Loss of adaptive myelination contributes to methotrexate chemotherapy-related cognitive impairment AC Geraghty, EM Gibson, RA Ghanem, JJ Greene, A Ocampo, ... Neuron 103 (2), 250-265. e8, 2019 | 229 | 2019 |
Organoid and assembloid technologies for investigating cellular crosstalk in human brain development and disease RM Marton, SP Pașca Trends in Cell Biology 30 (2), 133-143, 2020 | 214 | 2020 |