| A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis L Che, P Liu, M Ge, J Hu, X Li, K Sun, L Cheng, Y Huang, MG Pilo, ... Hepatology 66 (1), 167–181, 2017 | 170 | 2017 |
| Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans LI Che, W Chi, Y Qiao, J Zhang, X Song, YE Liu, L Li, J Jia, MG Pilo, ... Gut 69 (1), 177-186, 2020 | 167 | 2020 |
| Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans L LI, GM Pilo, X Li, A Cigliano, G Latte, L Che, C Joseph, M Mela, C Wang, ... Journal of Hepatology 64 (2), 333-341, 2016 | 145 | 2016 |
| Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice L Che, J Hu, L Li, MG Pilo, A Cigliano, S Ribback, X Li, G Latte, M Mela, ... Scientific Reports, 9;6:20484, 2016 | 121 | 2016 |
| Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ... Journal of Hepatology, [Epub ahead of print], 2017 | 110 | 2017 |
| The mTORC2‐Akt1 cascade is crucial for c‐Myc to promote hepatocarcinogenesis in mice and humans Z Xu, M Xu, P Liu, S Zhang, R Shang, Y Qiao, L Che, S Ribback, ... Hepatology 70 (5), 1600-1613, 2019 | 106 | 2019 |
| Differential effects of targeting Notch receptors in a mouse model of liver cancer EG Huntzicker, K Hötzel, L Choy, L Che, J Ross, G Pau, N Sharma, ... Hepatology 61 (3), 942–952, 2015 | 105 | 2015 |
| Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice J Wang, M Dong, Z Xu, X Song, S Zhang, YU Qiao, L Che, J Gordan, K Hu, ... Oncogene 37 (24), 3229-3242, 2018 | 103 | 2018 |
| Differential Requirement for de novo Lipogenesis in Cholangiocarcinoma and Hepatocellular Carcinoma of Mice and Humans L Che, L Li, KM Tharp, HM Park, MG Pilo, D Cao, A Cigliano, G Latte, Z Xu, ... Hepatology 63 (6), 1900-1913, 2016 | 97 | 2016 |
| Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma R Shang, X Song, P Wang, Y Zhou, X Lu, J Wang, M Xu, X Chen, ... Gut 70 (9), 1746-1757, 2021 | 88 | 2021 |
| Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities A Méndez-Lucas, X Li, J Hu, L Che, X Song, J Jia, J Wang, C Xie, ... Cancer research 77 (16), 4355-4364, 2017 | 85 | 2017 |
| Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free … J Ren, L Di, G Song, J Yu, J Jia, Y Zhu, Y Yan, H Jiang, X Liang, L Che, ... Clinical and Translational Oncology 15 (10), 780-788, 2013 | 79 | 2013 |
| Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells D Cao, X Song, L Che, X Li, MG Pilo, G Vidili, A Porcu, A Solinas, ... Liver International 37 (1), 80–89, 2016 | 77 | 2016 |
| Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma X Song, X Liu, H Wang, J Wang, Y Qiao, A Cigliano, K Utpatel, S Ribback, ... Clinical Cancer Research 25 (1), 403-413, 2019 | 73 | 2019 |
| MicroRNA‐206 Prevents the Pathogenesis of Hepatocellular Carcinoma Via Modulating Expression of cMet and Cdk6 H Wu, J Tao, X Li, T Zhang, L Zhao, J Xiong, Z Zeng, N Zhan, L Che, ... Hepatology, [Epub ahead of print], 2017 | 73 | 2017 |
| Activation of sonic hedgehog signaling pathway is an independent potential prognosis predictor in human hepatocellular carcinoma patients L Che, Y Yuan, J Jia, J Ren CHINSES JOURNAL OF CANCER RESEARCH 24 (4), 323–331, 2012 | 72 | 2012 |
| Pathogenetic, prognostic, and therapeutic role of fatty acid synthase in human hepatocellular carcinoma L Che, P Paliogiannis, A Cigliano, MG Pilo, X Chen, DF Calvisi Frontiers in oncology 9, 1412, 2019 | 65 | 2019 |
| Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation X Song, H Xu, P Wang, J Wang, S Affo, H Wang, M Xu, B Liang, L Che, ... Journal of hepatology 75 (4), 888-899, 2021 | 60 | 2021 |
| Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma G Hale, X Liu, J Hu, Z Xu, L Che, D Solomon, C Tsokos, N Shafizadeh, ... Modern Pathology 29, 1370–1380, 2016 | 59 | 2016 |
| Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis J Wang, H Wang, M Peters, N Ding, S Ribback, K Utpatel, A Cigliano, ... Journal of hepatology 71 (4), 742-752, 2019 | 58 | 2019 |
Jingxiao WangStanford UniversityVerified email at stanford.edu