CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability BJ Lannutti, SA Meadows, SEM Herman, A Kashishian, B Steiner, ... Blood, The Journal of the American Society of Hematology 117 (2), 591-594, 2011 | 885 | 2011 |
Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival … SEM Herman, AL Gordon, AJ Wagner, NA Heerema, W Zhao, JM Flynn, ... Blood, The Journal of the American Society of Hematology 116 (12), 2078-2088, 2010 | 738 | 2010 |
Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease J Kinchen, HH Chen, K Parikh, A Antanaviciute, M Jagielowicz, ... Cell 175 (2), 372-386. e17, 2018 | 631 | 2018 |
Adhesion through L-selectin requires a threshold hydrodynamic shear EB Finger, KD Purl, R Alon, MB Lawrence, UH von Andrian, TA Springer Nature 379 (6562), 266-269, 1996 | 621 | 1996 |
The kinetics of L-selectin tethers and the mechanics of selectin-mediated rolling R Alon, S Chen, KD Puri, EB Finger, TA Springer The Journal of cell biology 138 (5), 1169-1180, 1997 | 462 | 1997 |
Platelet-mediated lymphocyte delivery to high endothelial venules TG Diacovo, KD Puri, RA Warnock, TA Springer, UH Von Andrian Science 273 (5272), 252-255, 1996 | 395 | 1996 |
Inhibition of phosphoinositide 3‐kinase δ attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model KS Lee, HK Lee, JS Hayflick, YC Lee, KD Puri The FASEB journal 20 (3), 455-465, 2006 | 334 | 2006 |
Thermodynamics of monosaccharide binding to concanavalin A, pea (Pisum sativum) lectin, and lentil (Lens culinaris) lectin. FP Schwarz, KD Puri, RG Bhat, A Surolia Journal of Biological Chemistry 268 (11), 7668-7677, 1993 | 297 | 1993 |
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling SA Omori, MH Cato, A Anzelon-Mills, KD Puri, M Shapiro-Shelef, ... Immunity 25 (4), 545-557, 2006 | 277 | 2006 |
PI3K/p110δ is a novel therapeutic target in multiple myeloma H Ikeda, T Hideshima, M Fulciniti, G Perrone, N Miura, H Yasui, Y Okawa, ... Blood, The Journal of the American Society of Hematology 116 (9), 1460-1468, 2010 | 276 | 2010 |
Mechanisms and implications of phosphoinositide 3-kinase δ in promoting neutrophil trafficking into inflamed tissue KD Puri, TA Doggett, J Douangpanya, Y Hou, WT Tino, T Wilson, T Graf, ... Blood 103 (9), 3448-3456, 2004 | 266 | 2004 |
The role of endothelial PI3Kγ activity in neutrophil trafficking KD Puri, TA Doggett, CY Huang, J Douangpanya, JS Hayflick, M Turner, ... Blood 106 (1), 150-157, 2005 | 204 | 2005 |
Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules. KD Puri, EB Finger, G Gaudernack, TA Springer Journal of Cell Biology 131 (1), 261-270, 1995 | 198 | 1995 |
PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP B Heit, L Liu, P Colarusso, KD Puri, P Kubes Journal of cell science 121 (2), 205-214, 2008 | 183 | 2008 |
Methods of inhibiting immune responses stimulated by an endogenous factor J Douangpanya, J Hayflick, K Puri US Patent App. 10/918,803, 2005 | 170 | 2005 |
Phosphoinositide 3-Kinase Inhibitors for Inhibiting Leukocyte Accumulation TG Diacovo, JS Hayflick, KD Puri US Patent App. 11/884,566, 2008 | 169 | 2008 |
The kinetics and shear threshold of transient and rolling interactions of L-selectin with its ligand on leukocytes R Alon, S Chen, R Fuhlbrigge, KD Puri, TA Springer Proceedings of the National Academy of Sciences 95 (20), 11631-11636, 1998 | 169 | 1998 |
Role of PI3Kδ and PI3Kγ in inflammatory arthritis and tissue localization of neutrophils TM Randis, KD Puri, H Zhou, TG Diacovo European journal of immunology 38 (5), 1215-1224, 2008 | 164 | 2008 |
P-selectin, L-selectin, and alpha 4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions. J Kitayama, RC Fuhlbrigge, KD Puri, TA Springer Journal of immunology (Baltimore, Md.: 1950) 159 (8), 3929-3939, 1997 | 145 | 1997 |
Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions. RC Fuhlbrigge, R Alon, KD Puri, JB Lowe, TA Springer The Journal of cell biology 135 (3), 837-848, 1996 | 145 | 1996 |