| The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism MG Iadanza, R Silvers, J Boardman, HI Smith, TK Karamanos, ... Nature Communications 9 (1), 4517, 2018 | 139 | 2018 |
| Mechanisms of amyloid formation revealed by solution NMR TK Karamanos, AP Kalverda, GS Thompson, SE Radford Progress in nuclear magnetic resonance spectroscopy 88, 86-104, 2015 | 134 | 2015 |
| Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo CL Dobson, PWA Devine, JJ Phillips, DR Higazi, C Lloyd, B Popovic, ... Scientific reports 6 (1), 1-14, 2016 | 127 | 2016 |
| pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers KW Tipping, TK Karamanos, T Jakhria, MG Iadanza, SC Goodchild, ... Proceedings of the National Academy of Sciences 112 (18), 5691-5696, 2015 | 127 | 2015 |
| Visualizing and trapping transient oligomers in amyloid assembly pathways EE Cawood, TK Karamanos, AJ Wilson, SE Radford Biophysical chemistry 268, 106505, 2021 | 111 | 2021 |
| Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis TK Karamanos, V Tugarinov, GM Clore Proceedings of the National Academy of Sciences 116 (43), 21529-21538, 2019 | 76 | 2019 |
| Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly TK Karamanos, AP Kalverda, GS Thompson, SE Radford Molecular cell 55 (2), 214-226, 2014 | 67 | 2014 |
| Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients AN Calabrese, B Schiffrin, M Watson, TK Karamanos, M Walko, ... Nature Communications 11 (1), 1-16, 2020 | 62 | 2020 |
| Structural mapping of oligomeric intermediates in an amyloid assembly pathway TK Karamanos, MP Jackson, AN Calabrese, SC Goodchild, EE Cawood, ... Elife 8, e46574, 2019 | 57 | 2019 |
| A population shift between sparsely populated folding intermediates determines amyloidogenicity TK Karamanos, CL Pashley, AP Kalverda, GS Thompson, M Mayzel, ... Journal of the American Chemical Society 138 (19), 6271-6280, 2016 | 39 | 2016 |
| An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a β sheet backbone TK Karamanos, V Tugarinov, GM Clore Proceedings of the National Academy of Sciences 117 (48), 30441-30450, 2020 | 30 | 2020 |
| Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins EM Martin, MP Jackson, M Gamerdinger, K Gense, TK Karamonos, ... Journal of Biological Chemistry 293 (22), 8554-8568, 2018 | 26 | 2018 |
| Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding B Schiffrin, JM Machin, TK Karamanos, A Zhuravleva, DJ Brockwell, ... Communications Biology 5 (1), 560, 2022 | 25 | 2022 |
| Modulation of amyloidogenic protein self-assembly using tethered small molecules EE Cawood, N Guthertz, JS Ebo, TK Karamanos, SE Radford, AJ Wilson Journal of the American Chemical Society 142 (49), 20845-20854, 2020 | 25 | 2020 |
| Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation N Benseny-Cases, TK Karamanos, CL Hoop, J Baum, SE Radford Journal of Biological Chemistry 294 (24), 9392-9401, 2019 | 23 | 2019 |
| Structural studies of “aggregation‐prone” peptide‐analogues of teleostean egg chorion ZPB proteins NN Louros, N Petronikolou, T Karamanos, P Cordopatis, VA Iconomidou, ... Peptide Science 102 (6), 427-436, 2014 | 18 | 2014 |
| Magic‐Angle‐Pulse Driven Separation of Degenerate 1H Transitions in Methyl Groups of Proteins: Application to Studies of Methyl Axis Dynamics V Tugarinov, TK Karamanos, GM Clore ChemPhysChem 21 (11), 1087-1091, 2020 | 16 | 2020 |
| Microsecond backbone motions modulate the oligomerization of the Dnajb6 chaperone EE Cawood, GM Clore, TK Karamanos Angewandte Chemie 134 (20), e202116403, 2022 | 14 | 2022 |
| Generating ensembles of dynamic misfolding proteins TK Karamanos, AP Kalverda, SE Radford Frontiers in Neuroscience 16, 881534, 2022 | 14 | 2022 |
| Distinguishing Closely Related Amyloid Precursors Using an RNA Aptamer CJ Sarell, TK Karamanos, SJ White, DHJ Bunka, AP Kalverda, ... Journal of Biological Chemistry 289 (39), 26859-26871, 2014 | 13 | 2014 |
Sheena RadfordThe University of LeedsVerified email at leeds.ac.uk
