Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications T Thomas*, TJ Thomas Cellular and Molecular Life Sciences CMLS 58, 244-258, 2001 | 1149 | 2001 |
DNA nanoparticles and development of DNA delivery vehicles for gene therapy V Vijayanathan, T Thomas, TJ Thomas Biochemistry 41 (48), 14085-14094, 2002 | 505 | 2002 |
Polyamine metabolism and cancer T Thomas, TJ Thomas Journal of cellular and molecular medicine 7 (2), 113-126, 2003 | 437 | 2003 |
DNA condensation by polyamines: a laser light scattering study of structural effects V Vijayanathan, T Thomas, A Shirahata, TJ Thomas Biochemistry 40 (45), 13644-13651, 2001 | 237 | 2001 |
Polyamine analogues bind human serum albumin R Beauchemin, CN N'Soukpoe-Kossi, TJ Thomas, T Thomas, ... Biomacromolecules 8 (10), 3177-3183, 2007 | 205 | 2007 |
Ionic and structural specificity effects of natural and synthetic polyamines on the aggregation and resolubilization of single-, double-, and triple-stranded DNA M Saminathan, T Antony, A Shirahata, LH Sigal, T Thomas, TJ Thomas Biochemistry 38 (12), 3821-3830, 1999 | 200 | 1999 |
Selectivity of polyamines in triplex DNA stabilization T Thomas, TJ Thomas Biochemistry 32 (50), 14068-14074, 1993 | 179 | 1993 |
Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells. S Balabhadrapathruni, TJ Thomas, EJ Yurkow, PS Amenta, T Thomas Oncology reports 7 (1), 3-15, 2000 | 173 | 2000 |
Attractive forces between cation condensed DNA double helices BA Todd, VA Parsegian, A Shirahata, TJ Thomas, DC Rau Biophysical journal 94 (12), 4775-4782, 2008 | 156 | 2008 |
Biodegradable polymers for gene delivery TJ Thomas, HA Tajmir-Riahi, CKS Pillai Molecules 24 (20), 3744, 2019 | 140 | 2019 |
Ionic and structural effects on the thermal helix‐coil transition of DNA complexed with natural and synthetic polyamines TJ Thomas, VA Bloomfield Biopolymers: Original Research on Biomolecules 23 (7), 1295-1306, 1984 | 136 | 1984 |
Structural specificity of polyamines in left-handed Z-DNA formation: immunological and spectroscopic studies TJ Thomas, RP Messner Journal of molecular biology 201 (2), 463-467, 1988 | 123 | 1988 |
Collapse of DNA caused by trivalent cations: pH and ionic specificity effects TJ Thomas, VA Bloomfield Biopolymers: Original Research on Biomolecules 22 (4), 1097-1106, 1983 | 123 | 1983 |
Biogenic and synthetic polyamines bind bovine serum albumin S Dubeau, P Bourassa, TJ Thomas, HA Tajmir-Riahi Biomacromolecules 11 (6), 1507-1515, 2010 | 117 | 2010 |
Polyamine-induced B-DNA to Z-DNA conformational transition of a plasmid DNA with (dG-dC) n insert. TJ Thomas, UB Gunnia, T Thomas Journal of Biological Chemistry 266 (10), 6137-6141, 1991 | 116 | 1991 |
Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin P Bourassa, S Dubeau, GM Maharvi, AH Fauq, TJ Thomas, ... Biochimie 93 (7), 1089-1101, 2011 | 108 | 2011 |
DNA interaction with antitumor polyamine analogues: a comparison with biogenic polyamines CN N’Soukpoe-Kossi, AA Ouameur, T Thomas, A Shirahata, TJ Thomas, ... Biomacromolecules 9 (10), 2712-2718, 2008 | 107 | 2008 |
Formation of DNA nanoparticles in the presence of novel polyamine analogues: a laser light scattering and atomic force microscopic study V Vijayanathan, T Thomas, T Antony, A Shirahata, TJ Thomas Nucleic acids research 32 (1), 127-134, 2004 | 104 | 2004 |
Polyamine structural effects on the induction and stabilization of liquid crystalline DNA: potential applications to DNA packaging, gene therapy and polyamine therapeutics M Saminathan, T Thomas, A Shirahata, CKS Pillai, TJ Thomas Nucleic acids research 30 (17), 3722-3731, 2002 | 104 | 2002 |
Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells T Thomas, TJ Thomas Cancer research 54 (4), 1077-1084, 1994 | 103 | 1994 |