| GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects K Platzer, H Yuan, H Schütz, A Winschel, W Chen, C Hu, H Kusumoto, ... Journal of medical genetics 54 (7), 460-470, 2017 | 259 | 2017 |
| Human GRIN2B variants in neurodevelopmental disorders C Hu, W Chen, SJ Myers, H Yuan, SF Traynelis Journal of pharmacological sciences 132 (2), 115-121, 2016 | 245 | 2016 |
| Mechanistic insight into NMDA receptor dysregulation by rare variants in the GluN2A and GluN2B agonist binding domains SA Swanger, W Chen, G Wells, PB Burger, A Tankovic, S Bhattacharya, ... The American Journal of Human Genetics 99 (6), 1261-1280, 2016 | 179 | 2016 |
| GRIN2D recurrent de novo dominant mutation causes a severe epileptic encephalopathy treatable with NMDA receptor channel blockers D Li, H Yuan, XR Ortiz-Gonzalez, ED Marsh, L Tian, EM McCormick, ... The American Journal of Human Genetics 99 (4), 802-816, 2016 | 172 | 2016 |
| Molecular mechanism of disease-associated mutations in the pre-M1 helix of NMDA receptors and potential rescue pharmacology KK Ogden, W Chen, SA Swanger, MJ McDaniel, LZ Fan, C Hu, ... PLoS genetics 13 (1), e1006536, 2017 | 129 | 2017 |
| De novo mutations in GRIN1 cause extensive bilateral polymicrogyria AE Fry, KA Fawcett, N Zelnik, H Yuan, BAN Thompson, L Shemer-Meiri, ... Brain 141 (3), 698-712, 2018 | 99 | 2018 |
| A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia K Gao, A Tankovic, Y Zhang, H Kusumoto, J Zhang, W Chen, W XiangWei, ... PLoS One 12 (2), e0170818, 2017 | 74 | 2017 |
| De novo GRIN variants in NMDA receptor M2 channel pore‐forming loop are associated with neurological diseases J Li, J Zhang, W Tang, RK Mizu, H Kusumoto, W XiangWei, Y Xu, W Chen, ... Human mutation 40 (12), 2393-2413, 2019 | 70 | 2019 |
| Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias C Hu, CA Leche, A Kiyatkin, Z Yu, SE Stayrook, KM Ferguson, ... Nature 602 (7897), 518-522, 2022 | 69 | 2022 |
| Insulin and epidermal growth factor receptor family members share parallel activation mechanisms KM Ferguson, C Hu, MA Lemmon Protein Science 29 (6), 1331-1344, 2020 | 38 | 2020 |
| De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor Y Xu, R Song, RE Perszyk, W Chen, S Kim, KL Park, JP Allen, KA Nocilla, ... Cellular and Molecular Life Sciences 81 (1), 153, 2024 | 12 | 2024 |
| Effects of Selective M1 Muscarinic Receptor Activation on Hippocampal Spatial Representations and Neuronal Oscillations EP Lebois, JB Trimper, C Hu, AI Levey, JR Manns ACS chemical neuroscience 7 (10), 1393-1405, 2016 | 11 | 2016 |
| Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes KC Mudumbi, EA Burns, DJ Schodt, ZO Petrova, A Kiyatkin, LW Kim, ... Cell reports 43 (1), 2024 | 10 | 2024 |
| Understanding Distinct Roles of EGFR Family Mutations in Different Cancers C Hu Yale University, 2022 | | 2022 |
| Glioblastoma mutations impair ligand discrimination by EGFR C Hu, CA Leche, A Kiyatkin, SE Stayrook, KM Ferguson, MA Lemmon bioRxiv, 2021.05. 04.442654, 2021 | | 2021 |
| TIL Transcriptomic States Enable Successful TCR Prediction C Hu, CA Leche 2nd, A Kiyatkin, Z Yu, SE Stayrook, KM Ferguson | | |
