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Available somewhere: 23
Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy
M Sukumar, J Liu, GU Mehta, SJ Patel, R Roychoudhuri, JG Crompton, ...
Cell metabolism 23 (1), 63-76, 2016
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15
AM Ring, JX Lin, D Feng, S Mitra, M Rickert, GR Bowman, VS Pande, P Li, ...
Nature immunology 13 (12), 1187-1195, 2012
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity
D Hermans, S Gautam, JC García-Cañaveras, D Gromer, S Mitra, ...
Proceedings of the National Academy of Sciences 117 (11), 6047-6055, 2020
Mandates: US National Institutes of Health, European Commission
Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps
S Mitra, AM Ring, S Amarnath, JB Spangler, P Li, W Ju, S Fischer, J Oh, ...
Immunity 42 (5), 826-838, 2015
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression
W Liao, R Spolski, P Li, N Du, EE West, M Ren, S Mitra, WJ Leonard
Proceedings of the National Academy of Sciences 111 (9), 3508-3513, 2014
Mandates: US National Institutes of Health
An engineered IL-2 partial agonist promotes CD8+ T cell stemness
F Mo, Z Yu, P Li, J Oh, R Spolski, L Zhao, CR Glassman, TN Yamamoto, ...
Nature 597 (7877), 544-548, 2021
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Biology of IL-2 and its therapeutic modulation: Mechanisms and strategies
S Mitra, WJ Leonard
Journal of leukocyte biology 103 (4), 643-655, 2018
Mandates: US National Institutes of Health
Molecular profiling of driver events in metastatic uveal melanoma
J Karlsson, LM Nilsson, S Mitra, S Alsén, GV Shelke, VR Sah, ...
Nature communications 11 (1), 1894, 2020
Mandates: Knut and Alice Wallenberg Foundation, Swedish Research Council
STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus
P Li, S Mitra, R Spolski, J Oh, W Liao, Z Tang, F Mo, X Li, EE West, ...
Proceedings of the National Academy of Sciences 114 (46), 12111-12119, 2017
Mandates: US National Institutes of Health
Necroptosis in Niemann–Pick disease, type C1: a potential therapeutic target
A Cougnoux, C Cluzeau, S Mitra, R Li, I Williams, K Burkert, X Xu, ...
Cell death & disease 7 (3), e2147-e2147, 2016
Mandates: US National Institutes of Health
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses
C Gorby, J Sotolongo Bellón, S Wilmes, W Warda, E Pohler, PK Fyfe, ...
Science signaling 13 (649), eabc0653, 2020
Mandates: US National Institutes of Health, German Research Foundation, Wellcome Trust …
Cytokines orchestrating the natural killer-myeloid cell crosstalk in the tumor microenvironment: implications for natural killer cell-based cancer immunotherapy
S Gaggero, K Witt, M Carlsten, S Mitra
Frontiers in immunology 11, 621225, 2021
Mandates: Swedish Research Council
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells
R Nasrallah, CJ Imianowski, L Bossini-Castillo, FM Grant, M Dogan, ...
Nature 583 (7816), 447-452, 2020
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein
S Gaggero, J Martinez-Fabregas, A Cozzani, PK Fyfe, M Leprohon, ...
Science immunology 7 (78), eade5686, 2022
Mandates: German Research Foundation, National Institute of Health and Medical …
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
J Martinez-Fabregas, S Wilmes, L Wang, M Hafer, E Pohler, J Lokau, ...
Elife 8, e49314, 2019
Mandates: US National Institutes of Health, German Research Foundation, Wellcome Trust …
Effective anti-BCMA retreatment in multiple myeloma
N Gazeau, D Beauvais, I Yakoub-Agha, S Mitra, TB Campbell, T Facon, ...
Blood Advances 5 (15), 3016-3020, 2021
Mandates: US National Institutes of Health
Universal toxin-based selection for precise genome engineering in human cells
S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ...
Nature communications 12 (1), 497, 2021
Mandates: European Commission
CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci
J Martinez-Fabregas, L Wang, E Pohler, A Cozzani, S Wilmes, ...
Cell reports 33 (12), 2020
Mandates: US National Institutes of Health, Wellcome Trust, European Commission, Swiss …
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses
S Wilmes, PA Jeffrey, J Martinez-Fabregas, M Hafer, PK Fyfe, E Pohler, ...
Elife 10, e66014, 2021
Mandates: US Department of Energy, US National Institutes of Health, German Research …
Characterization of selective and potent JAK1 inhibitors intended for the inhaled treatment of asthma
M Nilsson, M Rhedin, R Hendrickx, S Berglund, A Piras, P Blomgran, ...
Drug design, development and therapy, 2901-2917, 2023
Mandates: National Institute of Health and Medical Research, France, Swedish Research …
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