| Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy M Sukumar, J Liu, GU Mehta, SJ Patel, R Roychoudhuri, JG Crompton, ... Cell metabolism 23 (1), 63-76, 2016 | 383 | 2016 |
| Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15 AM Ring, JX Lin, D Feng, S Mitra, M Rickert, GR Bowman, VS Pande, P Li, ... Nature immunology 13 (12), 1187-1195, 2012 | 299 | 2012 |
| Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity D Hermans, S Gautam, JC García-Cañaveras, D Gromer, S Mitra, ... Proceedings of the National Academy of Sciences 117 (11), 6047-6055, 2020 | 195 | 2020 |
| Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps S Mitra, AM Ring, S Amarnath, JB Spangler, P Li, W Ju, S Fischer, J Oh, ... Immunity 42 (5), 826-838, 2015 | 179 | 2015 |
| Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression W Liao, R Spolski, P Li, N Du, EE West, M Ren, S Mitra, WJ Leonard Proceedings of the National Academy of Sciences 111 (9), 3508-3513, 2014 | 170 | 2014 |
| An engineered IL-2 partial agonist promotes CD8+ T cell stemness F Mo, Z Yu, P Li, J Oh, R Spolski, L Zhao, CR Glassman, TN Yamamoto, ... Nature 597 (7877), 544-548, 2021 | 143 | 2021 |
| Biology of IL-2 and its therapeutic modulation: Mechanisms and strategies S Mitra, WJ Leonard Journal of leukocyte biology 103 (4), 643-655, 2018 | 139 | 2018 |
| Molecular profiling of driver events in metastatic uveal melanoma J Karlsson, LM Nilsson, S Mitra, S Alsén, GV Shelke, VR Sah, ... Nature communications 11 (1), 1894, 2020 | 132 | 2020 |
| First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio) S Yoon, S Mitra, C Wyse, A Alnabulsi, J Zou, EM Weerdenburg, ... PloS one 10 (6), e0126378, 2015 | 94 | 2015 |
| STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus P Li, S Mitra, R Spolski, J Oh, W Liao, Z Tang, F Mo, X Li, EE West, ... Proceedings of the National Academy of Sciences 114 (46), 12111-12119, 2017 | 93 | 2017 |
| Identification and characterization of the transcription factors involved in T‐cell development, t‐bet, stat6 and foxp3, within the zebrafish, Danio rerio S Mitra, A Alnabulsi, CJ Secombes, S Bird The FEBS journal 277 (1), 128-147, 2010 | 93 | 2010 |
| Cytokine‐regulated Th17 plasticity in human health and diseases S Cerboni, U Gehrmann, S Preite, S Mitra Immunology 163 (1), 3-18, 2021 | 91 | 2021 |
| Current state and next-generation CAR-T cells in multiple myeloma S Manier, T Ingegnere, G Escure, C Prodhomme, M Nudel, S Mitra, ... Blood Reviews 54, 100929, 2022 | 88 | 2022 |
| ESX‐5‐deficient Mycobacterium marinum is hypervirulent in adult zebrafish EM Weerdenburg, AM Abdallah, S Mitra, K De Punder, NN Van Der Wel, ... Cellular microbiology 14 (5), 728-739, 2012 | 87 | 2012 |
| Necroptosis in Niemann–Pick disease, type C1: a potential therapeutic target A Cougnoux, C Cluzeau, S Mitra, R Li, I Williams, K Burkert, X Xu, ... Cell death & disease 7 (3), e2147-e2147, 2016 | 68 | 2016 |
| Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses C Gorby, J Sotolongo Bellón, S Wilmes, W Warda, E Pohler, PK Fyfe, ... Science signaling 13 (649), eabc0653, 2020 | 67 | 2020 |
| Cytokines orchestrating the natural killer-myeloid cell crosstalk in the tumor microenvironment: implications for natural killer cell-based cancer immunotherapy S Gaggero, K Witt, M Carlsten, S Mitra Frontiers in immunology 11, 621225, 2021 | 56 | 2021 |
| A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells R Nasrallah, CJ Imianowski, L Bossini-Castillo, FM Grant, M Dogan, ... Nature 583 (7816), 447-452, 2020 | 56 | 2020 |
| IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein S Gaggero, J Martinez-Fabregas, A Cozzani, PK Fyfe, M Leprohon, ... Science immunology 7 (78), eade5686, 2022 | 50 | 2022 |
| Cellular apoptosis susceptibility (chromosome segregation 1‐like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer A Alnabulsi, A Agouni, S Mitra, I Garcia‐Murillas, B Carpenter, S Bird, ... The Journal of pathology 228 (4), 471-481, 2012 | 44 | 2012 |
Warren J. LeonardChief, Laboratory of Molecular Immunology and Director, Immunology Center, National Heart, Lung, andVerified email at helix.nih.gov