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Brian Leei Lin
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In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease
BL Lin, D Matera, JF Doerner, N Zheng, D Del Camino, S Mishra, H Bian, ...
Proceedings of the National Academy of Sciences 116 (20), 10156-10161, 2019
1292019
Wnt transmembrane signaling and long‐term spatial memory
N Tabatadze, C Tomas, R McGonigal, B Lin, A Schook, A Routtenberg
Hippocampus 22 (6), 1228-1241, 2012
792012
PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2
SA Murphy, M Miyamoto, A Kervadec, S Kannan, E Tampakakis, ...
Nature communications 12 (1), 1648, 2021
622021
Large particle fluorescence-activated cell sorting enables high-quality single-cell RNA sequencing and functional analysis of adult cardiomyocytes
S Kannan, M Miyamoto, BL Lin, R Zhu, S Murphy, DA Kass, P Andersen, ...
Circulation research 125 (5), 567-569, 2019
512019
Increase in cardiac myosin binding protein-C plasma levels is a sensitive and cardiac-specific biomarker of myocardial infarction
S Govindan, DWD Kuster, B Lin, DJ Kahn, WP Jeske, JM Walenga, ...
American journal of cardiovascular disease 3 (2), 60, 2013
502013
Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner
BL Lin, A Li, JY Mun, MJ Previs, SB Previs, SG Campbell, ...
Scientific reports 8 (1), 2604, 2018
442018
Cardiac myosin binding protein-C plays no regulatory role in skeletal muscle structure and function
B Lin, S Govindan, K Lee, P Zhao, R Han, KE Runte, R Craig, BM Palmer, ...
PLoS one 8 (7), e69671, 2013
422013
Myofilaments: movers and rulers of the sarcomere
BL Lin, T Song, S Sadayappan
Comprehensive Physiology, 675-692, 2011
422011
Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level
S Kannan, M Farid, BL Lin, M Miyamoto, C Kwon
PLoS computational biology 17 (9), e1009305, 2021
412021
PKG1α cysteine-42 redox state controls mTORC1 activation in pathological cardiac hypertrophy
CU Oeing, T Nakamura, S Pan, S Mishra, BL Dunkerly-Eyring, ...
Circulation research 127 (4), 522-533, 2020
362020
Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy
JG Boyer, J Huo, S Han, JR Havens, V Prasad, BL Lin, DA Kass, T Song, ...
Nature communications 13 (1), 2940, 2022
332022
Cardiac muscle organization revealed in 3-D by imaging whole-mount mouse hearts using two-photon fluorescence and confocal microscopy
M Sivaguru, G Fried, BS Sivaguru, VA Sivaguru, X Lu, KH Choi, MTA Saif, ...
Biotechniques 59 (5), 295-308, 2015
242015
Heart neurons use clock genes to control myocyte proliferation
E Tampakakis, H Gangrade, S Glavaris, M Htet, S Murphy, BL Lin, T Liu, ...
Science advances 7 (49), eabh4181, 2021
232021
Chronic atrial and ventricular pacing in the mouse: application to model cardiac dyssynchrony and resynchronization in heart failure
M Ståhlberg, R Nakagawa, D Bedja, G Zhu, BL Lin, A Saberi, DI Lee, ...
Circulation: Heart Failure 12 (2), e005655, 2019
232019
Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility
TL Lynch IV, M Kumar, JW McNamara, DWD Kuster, M Sivaguru, ...
Journal of molecular and cellular cardiology 156, 33-44, 2021
202021
HIF2A gain-of-function mutation modulates the stiffness of smooth muscle cells and compromises vascular mechanics
XY Chan, E Volkova, J Eoh, R Black, L Fang, R Gorashi, J Song, J Wang, ...
IScience 24 (4), 2021
192021
Pulmonary artery pulsatility index predicts right ventricular myofilament dysfunction in advanced human heart failure
MI Aslam, V Jani, B Lin, B Dunkerly-Eyring, CE Livingston, ...
European journal of heart failure 23 (2), 339, 2021
192021
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor
OE Reyes Gaido, N Pavlaki, JM Granger, OO Mesubi, B Liu, BL Lin, ...
Science translational medicine 15 (701), eabq7839, 2023
182023
Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy
BL Lin, JY Shin, WPD Jeffreys, N Wang, CA Lukban, MC Moorer, ...
JCI insight 7 (19), 2022
132022
Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription
S Irani, SN Sipe, W Yang, NT Burkholder, B Lin, K Sim, WL Matthews, ...
Journal of Biological Chemistry 294 (21), 8592-8605, 2019
122019
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