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Ryosuke Takahashi
Ryosuke Takahashi
Professor of Neurology, Kyoto University Graduate School of Medicine
Verified email at kuhp.kyoto-u.ac.jp
Title
Cited by
Cited by
Year
X-linked IAP is a direct inhibitor of cell-death proteases
QL Deveraux, R Takahashi, GS Salvesen, JC Reed
Nature 388 (6639), 300-304, 1997
27371997
The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases
N Roy, QL Deveraux, R Takahashi, GS Salvesen, JC Reed
The EMBO journal, 1997
17911997
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
Y Suzuki, Y Imai, H Nakayama, K Takahashi, K Takio, R Takahashi
Molecular cell 8 (3), 613-621, 2001
15262001
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
K Yamanaka, SJ Chun, S Boillee, N Fujimori-Tonou, H Yamashita, ...
Nature neuroscience 11 (3), 251-253, 2008
13462008
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
Y Imai, M Soda, H Inoue, N Hattori, Y Mizuno, R Takahashi
Cell 105 (7), 891-902, 2001
13052001
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
Y Imai, M Soda, R Takahashi
Journal of Biological Chemistry 275 (46), 35661-35664, 2000
9572000
A single BIR domain of XIAP sufficient for inhibiting caspases
R Takahashi, Q Deveraux, I Tamm, K Welsh, N Assa-Munt, GS Salvesen, ...
Journal of Biological Chemistry 273 (14), 7787-7790, 1998
9271998
Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced …
Y Suzuki, Y Nakabayashi, R Takahashi
Proceedings of the National Academy of Sciences 98 (15), 8662-8667, 2001
9022001
Modeling Alzheimer’s disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness
T Kondo, M Asai, K Tsukita, Y Kutoku, Y Ohsawa, Y Sunada, K Imamura, ...
Cell stem cell 12 (4), 487-496, 2013
8992013
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model
T Kikuchi, A Morizane, D Doi, H Magotani, H Onoe, T Hayashi, H Mizuma, ...
Nature 548 (7669), 592-596, 2017
7272017
Drug screening for ALS using patient-specific induced pluripotent stem cells
N Egawa, S Kitaoka, K Tsukita, M Naitoh, K Takahashi, T Yamamoto, ...
Science translational medicine 4 (145), 145ra104-145ra104, 2012
6552012
A rotarod test for evaluation of motor skill learning
H Shiotsuki, K Yoshimi, Y Shimo, M Funayama, Y Takamatsu, K Ikeda, ...
Journal of neuroscience methods 189 (2), 180-185, 2010
6312010
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
Y Imai, M Soda, S Hatakeyama, T Akagi, T Hashikawa, KI Nakayama, ...
Molecular cell 10 (1), 55-67, 2002
6132002
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
T Yokota, K Sugawara, K Ito, R Takahashi, H Ariga, H Mizusawa
Biochemical and biophysical research communications 312 (4), 1342-1348, 2003
5122003
Phosphorylation of 4E‐BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
Y Imai, S Gehrke, HQ Wang, R Takahashi, K Hasegawa, E Oota, B Lu
The EMBO journal 27 (18), 2432-2443, 2008
4952008
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
M Urushitani, A Sik, T Sakurai, N Nukina, R Takahashi, JP Julien
Nature neuroscience 9 (1), 108-118, 2006
4952006
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
Y Yang, S Gehrke, ME Haque, Y Imai, J Kosek, L Yang, MF Beal, ...
Proceedings of the National Academy of Sciences 102 (38), 13670-13675, 2005
4622005
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
Y Yang, I Nishimura, Y Imai, R Takahashi, B Lu
Neuron 37 (6), 911-924, 2003
4582003
Parkinson's disease–associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
S Liu, T Sawada, S Lee, W Yu, G Silverio, P Alapatt, I Millan, A Shen, ...
PLoS genetics 8 (3), e1002537, 2012
4112012
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
M Kajiwara, T Aoi, K Okita, R Takahashi, H Inoue, N Takayama, H Endo, ...
Proceedings of the National Academy of Sciences 109 (31), 12538-12543, 2012
3602012
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