| Rational design of cationic lipids for siRNA delivery SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DWY Sah, ... Nature biotechnology 28 (2), 172-176, 2010 | 1998 | 2010 |
| Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo M Jayaraman, SM Ansell, BL Mui, YK Tam, J Chen, X Du, D Butler, ... Angewandte Chemie 124 (34), 8657-8661, 2012 | 1267 | 2012 |
| On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids IM Hafez, N Maurer, PR Cullis Gene therapy 8 (15), 1188-1196, 2001 | 715 | 2001 |
| Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing IV Zhigaltsev, N Belliveau, I Hafez, AKK Leung, J Huft, C Hansen, ... Langmuir 28 (7), 3633-3640, 2012 | 426 | 2012 |
| Lipid nanoparticles containing siRNA synthesized by microfluidic mixing exhibit an electron-dense nanostructured core AKK Leung, IM Hafez, S Baoukina, NM Belliveau, IV Zhigaltsev, ... The Journal of Physical Chemistry C 116 (34), 18440-18450, 2012 | 353 | 2012 |
| Roles of lipid polymorphism in intracellular delivery IM Hafez, PR Cullis Advanced drug delivery reviews 47 (2-3), 139-148, 2001 | 333 | 2001 |
| Microfluidic mixing: a general method for encapsulating macromolecules in lipid nanoparticle systems AKK Leung, YYC Tam, S Chen, IM Hafez, PR Cullis The Journal of Physical Chemistry B 119 (28), 8698-8706, 2015 | 308 | 2015 |
| Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells G Basha, TI Novobrantseva, N Rosin, YYC Tam, IM Hafez, MK Wong, ... Molecular Therapy 19 (12), 2186-2200, 2011 | 259 | 2011 |
| Tunable pH-sensitive liposomes composed of mixtures of cationic and anionic lipids IM Hafez, S Ansell, PR Cullis Biophysical journal 79 (3), 1438-1446, 2000 | 237 | 2000 |
| Electrochemical imaging of fusion pore openings by electrochemical detector arrays I Hafez, K Kisler, K Berberian, G Dernick, V Valero, MG Yong, ... Proceedings of the National Academy of Sciences 102 (39), 13879-13884, 2005 | 162 | 2005 |
| Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior IM Hafez, PR Cullis Biochimica et Biophysica Acta (BBA)-Biomembranes 1463 (1), 107-114, 2000 | 156 | 2000 |
| Secretory vesicles membrane area is regulated in tandem with quantal size in chromaffin cells LW Gong, I Hafez, GA de Toledo, M Lindau Journal of Neuroscience 23 (21), 7917-7921, 2003 | 142 | 2003 |
| The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics Q Fang, K Berberian, LW Gong, I Hafez, JB Sørensen, M Lindau Proceedings of the National Academy of Sciences 105 (40), 15388-15392, 2008 | 117 | 2008 |
| Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA PJC Lin, YYC Tam, I Hafez, A Sandhu, S Chen, MA Ciufolini, IR Nabi, ... Nanomedicine: Nanotechnology, Biology and Medicine 9 (2), 233-246, 2013 | 113 | 2013 |
| Compound exocytosis and cumulative fusion in eosinophils I Hafez, A Stolpe, M Lindau Journal of Biological Chemistry 278 (45), 44921-44928, 2003 | 81 | 2003 |
| Nucleic acid-containing lipid particles and related methods PR Cullis, NM Belliveau, CLG Hansen, J Huft, J Taylor, A Wild, S Malcolm, ... US Patent 9,758,795, 2017 | 80 | 2017 |
| Methods and compositions for delivery of nucleic acids MJ Hope, TD Madden, PR Cullis, M Maier, M Jayaraman, KG Rajeev, ... US Patent App. 15/152,216, 2016 | 56 | 2016 |
| Dance of the SNAREs: assembly and rearrangements detected with FRET at neuronal synapses V Degtyar, IM Hafez, C Bray, RS Zucker Journal of Neuroscience 33 (13), 5507-5523, 2013 | 36 | 2013 |
| Tunable pH-sensitive liposomes IM Hafez, PR Cullis Methods in enzymology 387, 113-134, 2004 | 21 | 2004 |
| Differential regulation of exocytotic fusion and granule-granule fusion in eosinophils by Ca2+ and GTP analogs J Hartmann, S Scepek, I Hafez, M Lindau Journal of Biological Chemistry 278 (45), 44929-44934, 2003 | 21 | 2003 |
