Sustained cyclic AMP production by parathyroid hormone receptor endocytosis S Ferrandon, TN Feinstein, M Castro, B Wang, R Bouley, JT Potts, ... Nature chemical biology 5 (10), 734-742, 2009 | 620 | 2009 |
Measurement of the millisecond activation switch of G protein–coupled receptors in living cells JP Vilardaga, M Bünemann, C Krasel, M Castro, MJ Lohse Nature biotechnology 21 (7), 807-812, 2003 | 539 | 2003 |
Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism M Castro, VO Nikolaev, D Palm, MJ Lohse, JP Vilardaga Proceedings of the National Academy of Sciences of the United States of …, 2005 | 207 | 2005 |
Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13 L Jenkins, J Brea, NJ Smith, BD Hudson, G Reilly, NJ Bryant, M Castro, ... Biochemical Journal 432 (3), 451-459, 2010 | 115 | 2010 |
Human breast cancer cell line MDA‐MB‐231 expresses endogenous A2B adenosine receptors mediating a Ca2+ signal M Panjehpour, M Castro, KN Klotz British journal of pharmacology 145 (2), 211-218, 2005 | 112 | 2005 |
Ligand Residence Time at G-protein–Coupled Receptors—Why We Should Take Our Time To Study It C Hoffmann, M Castro, A Rinken, R Leurs, SJ Hill, HF Vischer Molecular pharmacology 88 (3), 552-560, 2015 | 86 | 2015 |
Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine2A receptor homodimers J Brea, M Castro, J Giraldo, JF López-Giménez, JF Padín, F Quintián, ... Molecular pharmacology 75 (6), 1380-1391, 2009 | 79 | 2009 |
G Protein–Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches HF Vischer, M Castro, JP Pin Molecular pharmacology 88 (3), 561-571, 2015 | 75 | 2015 |
Different architectures in the assembly of infectious bursal disease virus capsid proteins expressed in insect cells JL Martinez-Torrecuadrada, JR Castón, M Castro, JL Carrascosa, ... Virology 278 (2), 322-331, 2000 | 71 | 2000 |
Antibodies to the cloned mu-opioid receptor detect various molecular weight forms in areas of mouse brain. J Garzon, JL Juarros, MA Castro, P Sanchez-Blazquez Molecular pharmacology 47 (4), 738-744, 1995 | 69 | 1995 |
Structure‐Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics AA Kaczor, AG Silva, MI Loza, P Kolb, M Castro, A Poso ChemMedChem 11 (7), 718-729, 2016 | 60 | 2016 |
ETV5 cooperates with LPP as a sensor of extracellular signals and promotes EMT in endometrial carcinomas E Colas, L Muinelo-Romay, L Alonso-Alconada, M Llaurado, M Monge, ... Oncogene 31 (45), 4778-4788, 2012 | 58 | 2012 |
Gx/z and Gi2 transducer proteins on μ/δ opioid-mediated supraspinal antinociception P Sánchez-Blázquez, JL Juarros, Y Martínez-Peña, MA Castro, J Garzón Life sciences 53 (23), PL381-PL386, 1993 | 58 | 1993 |
Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and β-arrestins M Castro, F Dicker, JP Vilardaga, C Krasel, M Bernhardt, MJ Lohse Endocrinology 143 (10), 3854-3865, 2002 | 56 | 2002 |
Computer-Aided Structure-Based Design of Multitarget Leads for Alzheimer’s Disease JL Domínguez, F Fernández-Nieto, M Castro, M Catto, MR Paleo, S Porto, ... Journal of chemical information and modeling 55 (1), 135-148, 2014 | 55 | 2014 |
Extensive linkage disequilibrium mapping at HTR2A and DRD3 for schizophrenia susceptibility genes in the Galician population E Domínguez, MI Loza, F Padín, A Gesteira, E Paz, M Páramo, J Brenlla, ... Schizophrenia research 90 (1), 123-129, 2007 | 49 | 2007 |
Distinct phosphorylation sites on the ghrelin receptor, GHSR1a, establish a code that determines the functions of ß-arrestins M Bouzo-Lorenzo, I Santo-Zas, M Lodeiro, R Nogueiras, FF Casanueva, ... Scientific reports 6, 2016 | 48 | 2016 |
Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to μ receptors J Garzón, M Castro, P Sánchez‐Blázquez European Journal of Neuroscience 10 (8), 2557-2564, 1998 | 47 | 1998 |
In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1, 2, 3, 6-tetrahydropyridin-1-yl] methyl}-1, 2-dihydroquinolin-2-one (D2AAK1) as a … AA Kaczor, KM Targowska-Duda, B Budzyńska, G Biała, AG Silva, ... Neurochemistry international 96, 84-99, 2016 | 44 | 2016 |
New chromene scaffolds for adenosine A 2A receptors: Synthesis, pharmacology and structure–activity relationships F Areias, M Costa, M Castro, J Brea, E Gregori-Puigjané, MF Proença, ... European journal of medicinal chemistry 54, 303-310, 2012 | 43 | 2012 |