Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial HJL Heerspink, HH Parving, DL Andress, G Bakris, R Correa-Rotter, ... The Lancet 393 (10184), 1937-1947, 2019 | 572 | 2019 |
Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton T Takeda, T McQuistan, RA Orlando, MG Farquhar The Journal of clinical investigation 108 (2), 289-301, 2001 | 346 | 2001 |
Expression of podocalyxin inhibits cell–cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells T Takeda, WY Go, RA Orlando, MG Farquhar Molecular biology of the cell 11 (9), 3219-3232, 2000 | 274 | 2000 |
The glomerular epithelial cell anti-adhesin podocalyxin associates with the actin cytoskeleton through interactions with ezrin RA Orlando, T Takeda, B Zak, S Schmieder, VM Benoit, T McQuistan, ... Journal of the American Society of Nephrology 12 (8), 1589-1598, 2001 | 237 | 2001 |
Podocalyxin activates RhoA and induces actin reorganization through NHERF1 and Ezrin in MDCK cells S Schmieder, M Nagai, RA Orlando, T Takeda, MG Farquhar Journal of the American Society of Nephrology 15 (9), 2289-2298, 2004 | 160 | 2004 |
Identification of an apical sorting determinant in the cytoplasmic tail of megalin T Takeda, H Yamazaki, MG Farquhar American Journal of Physiology-Cell Physiology 284 (5), C1105-C1113, 2003 | 159 | 2003 |
Immunohistological evaluation of Ki‐67, p63, CK19 and p53 expression in oral epithelial dysplasias T Takeda, K Sugihara, Y Hirayama, M Hirano, JI Tanuma, I Semba Journal of oral pathology & medicine 35 (6), 369-375, 2006 | 148 | 2006 |
Japan renal biopsy registry and Japan kidney disease registry: committee report for 2009 and 2010 H Sugiyama, H Yokoyama, H Sato, T Saito, Y Kohda, S Nishi, K Tsuruya, ... Clinical and experimental nephrology 17, 155-173, 2013 | 133 | 2013 |
Molecular mechanisms of receptor‐mediated endocytosis in the renal proximal tubular epithelium A Saito, H Sato, N Iino, T Takeda BioMed Research International 2010 (1), 403272, 2010 | 131 | 2010 |
Megalin-mediated endocytosis of cystatin C in proximal tubule cells R Kaseda, N Iino, M Hosojima, T Takeda, K Hosaka, A Kobayashi, ... Biochemical and biophysical research communications 357 (4), 1130-1134, 2007 | 130 | 2007 |
The adaptor protein ARH escorts megalin to and through endosomes M Nagai, T Meerloo, T Takeda, MG Farquhar Molecular biology of the cell 14 (12), 4984-4996, 2003 | 130 | 2003 |
Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP X Zheng, X Wang, Z Ma, V Gupta Sunkari, I Botusan, T Takeda, ... Cell death & disease 3 (6), e322-e322, 2012 | 122 | 2012 |
Evidence for megalin-mediated proximal tubular uptake of L-FABP, a carrier of potentially nephrotoxic molecules Y Oyama, T Takeda, H Hama, A Tanuma, N Iino, K Sato, R Kaseda, M Ma, ... Laboratory Investigation 85 (4), 522-531, 2005 | 121 | 2005 |
Evidence indicating that renal tubular metabolism of leptin is mediated by megalin but not by the leptin receptors H Hama, A Saito, T Takeda, A Tanuma, Y Xie, K Sato, JJ Kazama, F Gejyo Endocrinology 145 (8), 3935-3940, 2004 | 118 | 2004 |
Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor-and insulin-mediated signaling cross talk M Hosojima, H Sato, K Yamamoto, R Kaseda, T Soma, A Kobayashi, ... Endocrinology 150 (2), 871-878, 2009 | 105 | 2009 |
Podocyte cytoskeleton is connected to the integral membrane protein podocalyxin through Na+/H+-exchanger regulatory factor 2 and ezrin T Takeda Journal of Clinical and Experimental Nephrology 7, 260-269, 2003 | 90 | 2003 |
Radiolucent bone cysts and the type of dialysis membrane used in patients undergoing long-term hemodialysis Y Miura, T Ishiyama, A Inomata, T Takeda, S Senma, K Okuyama, ... Nephron 60 (3), 268-273, 1992 | 87 | 1992 |
Significance of urinary full-length and ectodomain forms of megalin in patients with type 2 diabetes S Ogasawara, M Hosojima, R Kaseda, H Kabasawa, ... Diabetes Care 35 (5), 1112-1118, 2012 | 78 | 2012 |
Effect of treating hyperphosphatemia with lanthanum carbonate vs calcium carbonate on cardiovascular events in patients with chronic kidney disease undergoing hemodialysis: the … H Ogata, M Fukagawa, H Hirakata, T Kagimura, M Fukushima, T Akizawa, ... Jama 325 (19), 1946-1954, 2021 | 72 | 2021 |
Gαi3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins TS Weiss, CE Chamberlain, T Takeda, P Lin, KM Hahn, MG Farquhar Proceedings of the National Academy of Sciences 98 (26), 14961-14966, 2001 | 63 | 2001 |