Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors S Dallavalle, V Dobričić, L Lazzarato, E Gazzano, M Machuqueiro, ... Drug Resistance Updates 50, 100682, 2020 | 235 | 2020 |
Dual inhibitors of human DNA topoisomerase II and other cancer-related targets Z Skok, N Zidar, D Kikelj, J Ilaš Journal of medicinal chemistry 63 (3), 884-904, 2019 | 185 | 2019 |
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2, 4-dione inhibitors of MurD ligase N Zidar, T Tomašić, R Šink, V Rupnik, A Kovac, S Turk, D Patin, ... Journal of medicinal chemistry 53 (18), 6584-6594, 2010 | 127 | 2010 |
5‐Benzylidenethiazolidin‐4‐ones as multitarget inhibitors of bacterial Mur ligases T Tomašić, N Zidar, A Kovač, S Turk, M Simčič, D Blanot, ... ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 286-295, 2010 | 95 | 2010 |
Synthesis and antibacterial activity of 5-ylidenethiazolidin-4-ones and 5-benzylidene-4, 6-pyrimidinediones T Tomašić, N Zidar, M Mueller-Premru, D Kikelj, LP Mašič European Journal of Medicinal Chemistry 45 (4), 1667-1672, 2010 | 87 | 2010 |
Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues N Zidar, S Montalvão, Ž Hodnik, DA Nawrot, A Žula, J Ilaš, D Kikelj, ... Marine drugs 12 (2), 940-963, 2014 | 75 | 2014 |
N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation N Zidar, H Macut, T Tomasic, M Brvar, S Montalvao, P Tammela, ... Journal of medicinal chemistry 58 (15), 6179-6194, 2015 | 69 | 2015 |
Synthesis and Evaluation of N‐Phenylpyrrolamides as DNA Gyrase B Inhibitors M Durcik, P Tammela, M Barančoková, T Tomašič, J Ilaš, D Kikelj, N Zidar ChemMedChem 13 (2), 186-198, 2018 | 63 | 2018 |
Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus T Tomašić, R Šink, N Zidar, A Fic, C Contreras-Martel, A Dessen, ... ACS Medicinal Chemistry Letters 3 (8), 626-630, 2012 | 63 | 2012 |
Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase T Tomašić, N Zidar, V Rupnik, A Kovač, D Blanot, S Gobec, D Kikelj, ... Bioorganic & Medicinal Chemistry Letters 19 (1), 153-157, 2009 | 63 | 2009 |
Structure-Based Design of a New Series of d-Glutamic Acid Based Inhibitors of Bacterial UDP-N-acetylmuramoyl-l-alanine:d-glutamate Ligase (MurD) T Tomašić, N Zidar, R Sink, A Kovač, D Blanot, C Contreras-Martel, ... Journal of medicinal chemistry 54 (13), 4600-4610, 2011 | 62 | 2011 |
New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation N Zidar, T Tomašić, R Šink, A Kovač, D Patin, D Blanot, ... European journal of medicinal chemistry 46 (11), 5512-5523, 2011 | 61 | 2011 |
ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents M Durcik, T Tomašič, N Zidar, A Zega, D Kikelj, LP Mašič, J Ilaš Expert opinion on therapeutic patents 29 (3), 171-180, 2019 | 57 | 2019 |
New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity M Durcik, D Lovison, Ž Skok, CD Cruz, P Tammela, T Tomašič, DB Tiz, ... European journal of medicinal chemistry 154, 117-132, 2018 | 52 | 2018 |
Design, synthesis and biological evaluation of 4, 5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors T Tomašič, M Mirt, M Barančoková, J Ilaš, N Zidar, P Tammela, D Kikelj Bioorganic & medicinal chemistry 25 (1), 338-349, 2017 | 50 | 2017 |
Overcoming problems of poor drug penetration into bacteria: challenges and strategies for medicinal chemists D Benedetto Tiz, D Kikelj, N Zidar Expert Opinion on Drug Discovery 13 (6), 497-507, 2018 | 48 | 2018 |
Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells AH Pišlar, N Zidar, D Kikelj, J Kos Neuropharmacology 82, 121-131, 2014 | 48 | 2014 |
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors DB Tiz, Ž Skok, M Durcik, T Tomašič, LP Mašič, J Ilaš, A Zega, ... European journal of medicinal chemistry 167, 269-290, 2019 | 46 | 2019 |
Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation A Pišlar, B Božić, N Zidar, J Kos Neuropharmacology 114, 88-100, 2017 | 44 | 2017 |
New N-phenyl-4, 5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase N Zidar, T Tomašič, H Macut, A Sirc, M Brvar, S Montalvao, P Tammela, ... European Journal of Medicinal Chemistry 117, 197-211, 2016 | 41 | 2016 |