| Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls 1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ... Nature 447 (7145), 661-678, 2007 | 9501 | 2007 |
| A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ... Science 316 (5826), 889-894, 2007 | 5762 | 2007 |
| Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo … HM Colhoun, DJ Betteridge, PN Durrington, GA Hitman, HAW Neil, ... The Lancet 364 (9435), 685-696, 2004 | 5596 | 2004 |
| Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials CT Trialists The Lancet 376 (9753), 1670-1681, 2010 | 4431* | 2010 |
| Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ... Science 316 (5829), 1336-1341, 2007 | 2637 | 2007 |
| Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, ... Nature genetics 40 (5), 638-645, 2008 | 2319 | 2008 |
| Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ... Nature genetics 42 (7), 579-589, 2010 | 2204 | 2010 |
| Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ... Cell 97 (1), 133-144, 1999 | 1680 | 1999 |
| Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1452 | 2007 |
| Association of LDL cholesterol, non–HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis SM Boekholdt, BJ Arsenault, S Mora, TR Pedersen, JC LaRosa, PJ Nestel, ... Jama 307 (12), 1302-1309, 2012 | 1038 | 2012 |
| Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6. 2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant … AL Gloyn, MN Weedon, KR Owen, MJ Turner, BA Knight, G Hitman, ... Diabetes 52 (2), 568-572, 2003 | 1029 | 2003 |
| Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls Nature 464 (7289), 713-720, 2010 | 944 | 2010 |
| Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials SM Boekholdt, GK Hovingh, S Mora, BJ Arsenault, P Amarenco, ... Journal of the American College of Cardiology 64 (5), 485-494, 2014 | 841 | 2014 |
| Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials J Armitage, C Baigent, E Barnes, DJ Betteridge, L Blackwell, M Blazing, ... The Lancet 393 (10170), 407-415, 2019 | 748 | 2019 |
| Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ... Nature 450 (7171), 887-892, 2007 | 715 | 2007 |
| Circulating MMP9, vitamin D and variation in the TIMP‐1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders? PM Timms, N Mannan, GA Hitman, K Noonan, PG Mills, ... Qjm 95 (12), 787-796, 2002 | 692* | 2002 |
| Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis CT Trialists The Lancet 371 (9607), 117-125, 2008 | 684 | 2008 |
| Parental origin of sequence variants associated with complex diseases A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ... Nature 462 (7275), 868-874, 2009 | 669 | 2009 |
| Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ... PLoS genetics 8 (3), e1002607, 2012 | 577 | 2012 |
| Common variants in WFS1 confer risk of type 2 diabetes MS Sandhu, MN Weedon, KA Fawcett, J Wasson, SL Debenham, A Daly, ... Nature genetics 39 (8), 951-953, 2007 | 477 | 2007 |
