Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7651 | 2014 |
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder International Schizophrenia Consortium Manuscript preparation Purcell Shaun ... Nature 460 (7256), 748-752, 2009 | 5339 | 2009 |
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes MC O'Donovan Cell 72 (6), 971-983, 1993 | 5275 | 1993 |
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4584 | 2013 |
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3408 | 2009 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2780 | 2018 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2469 | 2019 |
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 2403 | 2013 |
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C Lin, L Srinidhi, ... Cell 72 (6), 971-983, 1993 | 2291 | 1993 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2247 | 2011 |
Genome-wide association study identifies five new schizophrenia loci Nature genetics 43 (10), 969-976, 2011 | 2040 | 2011 |
De novo mutations in schizophrenia implicate synaptic networks M Fromer, AJ Pocklington, DH Kavanagh, HJ Williams, S Dwyer, ... Nature 506 (7487), 179-184, 2014 | 1834 | 2014 |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ... Nature genetics 45 (10), 1150-1159, 2013 | 1785 | 2013 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1613 | 2022 |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ... Nature genetics 50 (3), 381-389, 2018 | 1594 | 2018 |
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 Nature genetics 43 (10), 977-983, 2011 | 1507 | 2011 |
Genetic architectures of psychiatric disorders: the emerging picture and its implications PF Sullivan, MJ Daly, M O'donovan Nature Reviews Genetics 13 (8), 537-551, 2012 | 1491 | 2012 |
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia CM Lewis, DF Levinson, LH Wise, LE DeLisi, RE Straub, I Hovatta, ... The American Journal of Human Genetics 73 (1), 34-48, 2003 | 1487 | 2003 |
Genome-wide association study identifies 30 loci associated with bipolar disorder EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ... Nature genetics 51 (5), 793-803, 2019 | 1483 | 2019 |
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder MAR Ferreira, MC O'Donovan, YA Meng, IR Jones, DM Ruderfer, L Jones, ... Nature genetics 40 (9), 1056-1058, 2008 | 1453 | 2008 |