| The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints R Fredriksson, MC Lagerström, LG Lundin, HB Schiöth Molecular pharmacology 63 (6), 1256-1272, 2003 | 4019 | 2003 |
| Trends in GPCR drug discovery: new agents, targets and indications AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam Nature reviews Drug discovery 16 (12), 829-842, 2017 | 2543 | 2017 |
| Structural diversity of G protein-coupled receptors and significance for drug discovery MC Lagerström, HB Schiöth Nature reviews Drug discovery 7 (4), 339-357, 2008 | 1897 | 2008 |
| HMDB 5.0: the human metabolome database for 2022 DS Wishart, AC Guo, E Oler, F Wang, A Anjum, H Peters, R Dizon, ... Nucleic acids research 50 (D1), D622-D631, 2022 | 1317 | 2022 |
| Trends in the exploitation of novel drug targets M Rask-Andersen, MS Almén, HB Schiöth Nature reviews Drug discovery 10 (8), 579-590, 2011 | 1059 | 2011 |
| Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin MS Almén, KJV Nordström, R Fredriksson, HB Schiöth BMC biology 7, 1-14, 2009 | 789 | 2009 |
| The repertoire of G-protein–coupled receptors in fully sequenced genomes R Fredriksson, HB Schiöth Molecular pharmacology 67 (5), 1414-1425, 2005 | 773 | 2005 |
| Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse TK Bjarnadóttir, DE Gloriam, SH Hellstrand, H Kristiansson, R Fredriksson, ... Genomics 88 (3), 263-273, 2006 | 578 | 2006 |
| Trends in kinase drug discovery: targets, indications and inhibitor design MM Attwood, D Fabbro, AV Sokolov, S Knapp, HB Schiöth Nature Reviews Drug Discovery 20 (11), 839-861, 2021 | 534 | 2021 |
| The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain R Fredriksson, M Hägglund, PK Olszewski, O Stephansson, ... Endocrinology 149 (5), 2062-2071, 2008 | 491 | 2008 |
| International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors J Hamann, G Aust, D Araç, FB Engel, C Formstone, R Fredriksson, ... Pharmacological reviews 67 (2), 338-367, 2015 | 489 | 2015 |
| The GRAFS classification system of G-protein coupled receptors in comparative perspective HB Schiöth, R Fredriksson General and comparative endocrinology 142 (1-2), 94-101, 2005 | 482 | 2005 |
| Ghrelin increases anxiety-like behavior and memory retention in rats VP Carlini, ME Monzón, MM Varas, AB Cragnolini, HB Schiöth, ... Biochemical and biophysical research communications 299 (5), 739-743, 2002 | 479 | 2002 |
| Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin VP Carlini, MM Varas, AB Cragnolini, HB Schiöth, TN Scimonelli, ... Biochemical and biophysical research communications 313 (3), 635-641, 2004 | 420 | 2004 |
| Seven evolutionarily conserved human rhodopsin G protein‐coupled receptors lacking close relatives R Fredriksson, PJ Höglund, DEI Gloriam, MC Lagerström, HB Schiöth FEBS letters 554 (3), 381-388, 2003 | 380 | 2003 |
| The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication M Rask-Andersen, S Masuram, HB Schiöth Annual review of pharmacology and toxicology 54 (1), 9-26, 2014 | 357 | 2014 |
| Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study C Benedict, SJ Brooks, OG O'Daly, MS Almen, A Morell, K Åberg, ... The Journal of Clinical Endocrinology & Metabolism 97 (3), E443-E447, 2012 | 354 | 2012 |
| Intranasal treatment of central nervous system dysfunction in humans CD Chapman, WH Frey, S Craft, L Danielyan, M Hallschmid, HB Schiöth, ... Pharmaceutical research 30, 2475-2484, 2013 | 345 | 2013 |
| Acute sleep deprivation reduces energy expenditure in healthy men C Benedict, M Hallschmid, A Lassen, C Mahnke, B Schultes, HB Schiöth, ... The American journal of clinical nutrition 93 (6), 1229-1236, 2011 | 340 | 2011 |
| The human and mouse repertoire of the adhesion family of G-protein-coupled receptors TK Bjarnadóttir, R Fredriksson, PJ Höglund, DE Gloriam, MC Lagerström, ... Genomics 84 (1), 23-33, 2004 | 320 | 2004 |
