NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials N Singh, B Manshian, GJS Jenkins, SM Griffiths, PM Williams, ... Biomaterials 30 (23-24), 3891-3914, 2009 | 1465 | 2009 |
Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION) N Singh, GJS Jenkins, R Asadi, SH Doak Nano reviews 1 (1), 5358, 2010 | 1237 | 2010 |
Graphene field‐effect transistor and its application for electronic sensing B Zhan, C Li, J Yang, G Jenkins, W Huang, X Dong Small 10 (20), 4042-4065, 2014 | 392 | 2014 |
Confounding experimental considerations in nanogenotoxicology SH Doak, SM Griffiths, B Manshian, N Singh, PM Williams, AP Brown, ... Mutagenesis 24 (4), 285-293, 2009 | 278 | 2009 |
In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines SH Doak, B Manshian, GJS Jenkins, N Singh Mutation Research/Genetic Toxicology and Environmental Mutagenesis 745 (1-2 …, 2012 | 274 | 2012 |
Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens SH Doak, GJS Jenkins, GE Johnson, E Quick, EM Parry, JM Parry Cancer research 67 (8), 3904-3911, 2007 | 215 | 2007 |
The bile acid deoxycholic acid (DCA) at neutral pH activates NF-κB and induces IL-8 expression in oesophageal cells in vitro GJS Jenkins, K Harries, SH Doak, A Wilmes, AP Griffiths, JN Baxter, ... Carcinogenesis 25 (3), 317-323, 2004 | 169 | 2004 |
The role of iron redox state in the genotoxicity of ultrafine superparamagnetic iron oxide nanoparticles N Singh, GJS Jenkins, BC Nelson, BJ Marquis, TGG Maffeis, AP Brown, ... Biomaterials 33 (1), 163-170, 2012 | 168 | 2012 |
Deoxycholic acid at neutral and acid pH, is genotoxic to oesophageal cells through the induction of ROS: the potential role of anti-oxidants in Barrett's oesophagus GJS Jenkins, FR D'Souza, SH Suzen, ZS Eltahir, SA James, JM Parry, ... Carcinogenesis 28 (1), 136-142, 2007 | 154 | 2007 |
Genetic pathways involved in the progression of Barrett's metaplasia to adenocarcinoma GJS Jenkins, SH Doak, JM Parry, FR D'Souza, AP Griffiths, JN Baxter British Journal of Surgery 89 (7), 824-837, 2002 | 142 | 2002 |
Do dose response thresholds exist for genotoxic alkylating agents? GJS Jenkins, SH Doak, GE Johnson, E Quick, EM Waters, JM Parry Mutagenesis 20 (6), 389-398, 2005 | 140 | 2005 |
A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies UK Shah, J de Oliveira Mallia, N Singh, KE Chapman, SH Doak, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 825, 51-58, 2018 | 119 | 2018 |
Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity SJ Evans, MJD Clift, N Singh, J de Oliveira Mallia, M Burgum, JW Wills, ... Mutagenesis 32 (1), 233-241, 2017 | 106 | 2017 |
Epidermal growth factor receptor (EGFR) is overexpressed in high-grade dysplasia and adenocarcinoma of the esophagus and may represent a biomarker of histological progression … J Cronin, E McAdam, A Danikas, C Tselepis, P Griffiths, J Baxter, ... Official journal of the American College of Gastroenterology| ACG 106 (1), 46-56, 2011 | 105 | 2011 |
The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF-κB activation in oesophageal cells, with a mechanism of action involving ROS GJS Jenkins, J Cronin, A Alhamdani, N Rawat, F D'souza, T Thomas, ... Mutagenesis 23 (5), 399-405, 2008 | 100 | 2008 |
Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett’s oesophagus SH Doak, GJS Jenkins, EM Parry, FR D’souza, AP Griffiths, N Toffazal, ... Gut 52 (5), 623-628, 2003 | 85 | 2003 |
Detection of p53 mutations in precancerous gastric tissue C Morgan, GJS Jenkins, T Ashton, AP Griffiths, JN Baxter, EM Parry, ... British journal of cancer 89 (7), 1314-1319, 2003 | 82 | 2003 |
Dextran coated ultrafine superparamagnetic iron oxide nanoparticles: compatibility with common fluorometric and colorimetric dyes SM Griffiths, N Singh, GJS Jenkins, PM Williams, AW Orbaek, AR Barron, ... Analytical chemistry 83 (10), 3778-3785, 2011 | 80 | 2011 |
Differential expression of the MAD2, BUB1 and HSP27 genes in Barrett’s oesophagus—their association with aneuploidy and neoplastic progression SH Doak, GJS Jenkins, EM Parry, AP Griffiths, JN Baxter, JM Parry Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 547 (1 …, 2004 | 76 | 2004 |
Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™) JW Wills, N Hondow, AD Thomas, KE Chapman, D Fish, TG Maffeis, ... Particle and fibre toxicology 13, 1-21, 2015 | 73 | 2015 |