Autophagy is an adaptive response in desmin-related cardiomyopathy P Tannous, H Zhu, JL Johnstone, JM Shelton, NS Rajasekaran, ... Proceedings of the National Academy of Sciences 105 (28), 9745-9750, 2008 | 266 | 2008 |
When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling LK Nguyen, W Kolch, BN Kholodenko Cell Communication and Signaling 11, 1-15, 2013 | 215 | 2013 |
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy BS Padman, TN Nguyen, L Uoselis, M Skulsuppaisarn, LK Nguyen, ... Nature communications 10 (1), 408, 2019 | 207 | 2019 |
Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ... Cell systems 2 (1), 38-48, 2016 | 181 | 2016 |
Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling D Romano, LK Nguyen, D Matallanas, M Halasz, C Doherty, ... Nature cell biology 16 (7), 673-684, 2014 | 161 | 2014 |
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network LK Nguyen, MAS Cavadas, CC Scholz, SF Fitzpatrick, U Bruning, ... Journal of cell science 126 (6), 1454-1463, 2013 | 159* | 2013 |
Rac1 and RhoA: Networks, loops and bistability LK Nguyen, BN Kholodenko, A Von Kriegsheim Small GTPases 9 (4), 316-321, 2018 | 108 | 2018 |
Substrate-trapped interactors of PHD3 and FIH cluster in distinct signaling pathways J Rodriguez, R Pilkington, AG Munoz, LK Nguyen, N Rauch, S Kennedy, ... Cell reports 14 (11), 2745-2760, 2016 | 102 | 2016 |
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 101 | 2019 |
Differential expression and functional analysis of Pitx2 isoforms in regulation of heart looping in the chick X Yu, TRS Amand, S Wang, G Li, Y Zhang, YP Hu, L Nguyen, MS Qiu, ... Development 128 (6), 1005-1013, 2001 | 96 | 2001 |
Hypoxia-inducible factor (HIF) network: insights from mathematical models MAS Cavadas, LK Nguyen, A Cheong Cell communication and signaling 11, 1-16, 2013 | 91 | 2013 |
Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function D He, H Xu, H Zhang, R Tang, Y Lan, R Xing, S Li, E Christian, Y Hou, ... Immunity 55 (1), 159-173. e9, 2022 | 77 | 2022 |
Signalling by protein phosphatases and drug development: a systems‐centred view LK Nguyen, D Matallanas, DR Croucher, A Von Kriegsheim, ... The FEBS journal 280 (2), 751-765, 2013 | 73 | 2013 |
Targeting of PYK2 synergizes with EGFR antagonists in basal-like TNBC and circumvents HER3-associated resistance via the NEDD4–NDRG1 axis N Verma, AK Müller, C Kothari, E Panayotopoulou, A Kedan, ... Cancer research 77 (1), 86-99, 2017 | 72 | 2017 |
Feedback regulation in cell signalling: Lessons for cancer therapeutics LK Nguyen, BN Kholodenko Seminars in cell & developmental biology 50, 85-94, 2016 | 70 | 2016 |
Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells MHG Raj, ZY Abd Elmageed, J Zhou, RL Gaur, L Nguyen, GA Azam, ... Gynecologic oncology 110 (3), 432-438, 2008 | 66 | 2008 |
Electrophysiological measures as potential biomarkers in Huntington's disease: review and future directions L Nguyen, JL Bradshaw, JC Stout, RJ Croft, N Georgiou-Karistianis Brain Research Reviews 64 (1), 177-194, 2010 | 65 | 2010 |
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease GS Basi, S Hemphill, EF Brigham, A Liao, DL Aubele, J Baker, R Barbour, ... Alzheimer's research & therapy 2, 1-21, 2010 | 63 | 2010 |
FGFR3 signaling and function in triple negative breast cancer NJ Chew, EV Nguyen, SP Su, K Novy, HC Chan, LK Nguyen, J Luu, ... Cell Communication and Signaling 18, 1-17, 2020 | 61 | 2020 |
Phosphorylation of RAF kinase dimers drives conformational changes that facilitate transactivation PG Jambrina, N Rauch, R Pilkington, K Rybakova, LK Nguyen, ... Angewandte Chemie 128 (3), 995-998, 2016 | 54 | 2016 |