Molecular tweezers modulate 14-3-3 protein–protein interactions D Bier, R Rose, K Bravo-Rodriguez, M Bartel, JM Ramirez-Anguita, S Dutt, ... Nature chemistry 5 (3), 234-239, 2013 | 206 | 2013 |
Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase U Sundermann, K Bravo-Rodriguez, S Klopries, S Kushnir, H Gomez, ... ACS chemical biology 8 (2), 443-450, 2013 | 128 | 2013 |
Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions A Sprengel, P Lill, P Stegemann, K Bravo-Rodriguez, EC Schöneweiß, ... Nature communications 8 (1), 14472, 2017 | 82 | 2017 |
A molecular tweezer antagonizes seminal amyloids and HIV infection E Lump, LM Castellano, C Meier, J Seeliger, N Erwin, B Sperlich, ... eLife 4, 2015 | 80 | 2015 |
Solvent-induced conformational changes in cyclic peptides: a vibrational circular dichroism study C Merten, F Li, K Bravo-Rodriguez, E Sanchez-Garcia, Y Xu, W Sander Physical Chemistry Chemical Physics 16 (12), 5627-5633, 2014 | 79 | 2014 |
Molecular tweezers with varying anions: a comparative study S Dutt, C Wilch, T Gersthagen, P Talbiersky, K Bravo-Rodriguez, M Hanni, ... The Journal of organic chemistry 78 (13), 6721-6734, 2013 | 75 | 2013 |
Substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis K Bravo-Rodriguez, S Klopries, KRM Koopmans, U Sundermann, ... Chemistry & biology 22 (11), 1425-1430, 2015 | 58 | 2015 |
Predicted Incorporation of Non‐native Substrates by a Polyketide Synthase Yields Bioactive Natural Product Derivatives K Bravo‐Rodriguez, AF Ismail‐Ali, S Klopries, S Kushnir, S Ismail, ... ChemBioChem 15 (13), 1991-1997, 2014 | 58 | 2014 |
The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface D Bier, S Mittal, K Bravo-Rodriguez, A Sowislok, X Guillory, J Briels, ... Journal of the American Chemical Society 139 (45), 16256-16263, 2017 | 57 | 2017 |
Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01 T Vöpel, K Bravo-Rodriguez, S Mittal, S Vachharajani, D Gnutt, ... Journal of the American Chemical Society 139 (16), 5640-5643, 2017 | 55 | 2017 |
Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism DHJ Lopes, A Attar, G Nair, EY Hayden, Z Du, K McDaniel, S Dutt, ... ACS chemical biology 10 (6), 1555-1569, 2015 | 55 | 2015 |
Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching AS Wagner, AZ Politi, A Ast, K Bravo-Rodriguez, K Baum, A Buntru, ... Journal of molecular biology 430 (12), 1725-1744, 2018 | 48 | 2018 |
Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization F Mueller, A Friese, C Pathe, RC da Silva, KB Rodriguez, A Musacchio, ... Science Advances 7 (3), eabc8590, 2021 | 45 | 2021 |
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers A Arumughan, Y Roske, C Barth, LL Forero, K Bravo-Rodriguez, A Redel, ... Nature Communications 7, 13047, 2016 | 40 | 2016 |
Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers T Weil, R Groß, A Röcker, K Bravo-Rodriguez, C Heid, A Sowislok, ... Journal of the American Chemical Society 142 (40), 17024-17038, 2020 | 37 | 2020 |
Molecular tweezers target a protein–protein interface and thereby modulate complex formation F Trusch, K Kowski, K Bravo-Rodriguez, C Beuck, A Sowislok, B Wettig, ... Chemical Communications 52 (98), 14141-14144, 2016 | 24 | 2016 |
Interactions of Aromatic Radicals with Water R Crespo‐Otero, K Bravo‐Rodriguez, S Roy, T Benighaus, W Thiel, ... ChemPhysChem 14 (4), 805-811, 2013 | 23 | 2013 |
Conformation and dynamics of a cyclic disulfide-bridged peptide: effects of temperature and solvent F Li, K Bravo-Rodriguez, C Phillips, RW Seidel, F Wieberneit, R Stoll, ... The Journal of Physical Chemistry B 117 (13), 3560-3570, 2013 | 21 | 2013 |
The Benzylperoxyl Radical as a Source of Hydroxyl and Phenyl Radicals W Sander, S Roy, K Bravo‐Rodriguez, D Grote, E Sanchez‐Garcia Chemistry-A European Journal 20 (40), 12917-12923, 2014 | 17 | 2014 |
The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease R Kosinski, JM Perez, EC Schöneweiß, YB Ruiz-Blanco, I Ponzo, ... Science Advances 8 (1), eabk0425, 2022 | 16 | 2022 |