| Creation of a bacterial cell controlled by a chemically synthesized genome DG Gibson, JI Glass, C Lartigue, VN Noskov, RY Chuang, MA Algire, ... science 329 (5987), 52-56, 2010 | 3512 | 2010 |
| Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors AJ Meyer, TH Segall-Shapiro, E Glassey, J Zhang, CA Voigt Nature chemical biology 15 (2), 196-204, 2019 | 481 | 2019 |
| Modular control of multiple pathways using engineered orthogonal T7 polymerases K Temme, R Hill, TH Segall-Shapiro, F Moser, CA Voigt Nucleic Acids Research, 2012 | 228 | 2012 |
| Design of orthogonal genetic switches based on a crosstalk map of σs, anti‐σs, and promoters VA Rhodius, TH Segall‐Shapiro, BD Sharon, A Ghodasara, E Orlova, ... Molecular systems biology 9 (1), 702, 2013 | 217 | 2013 |
| A ‘resource allocator’for transcription based on a highly fragmented T7 RNA polymerase TH Segall‐Shapiro, AJ Meyer, AD Ellington, ED Sontag, CA Voigt Molecular systems biology 10 (7), 742, 2014 | 207 | 2014 |
| Engineered promoters enable constant gene expression at any copy number in bacteria TH Segall-Shapiro, ED Sontag, CA Voigt Nature biotechnology 36 (4), 352-358, 2018 | 189 | 2018 |
| Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression AAK Nielsen, TH Segall-Shapiro, CA Voigt Current opinion in chemical biology 17 (6), 878-892, 2013 | 167 | 2013 |
| An adaptor from translational to transcriptional control enables predictable assembly of complex regulation CC Liu, L Qi, JB Lucks, TH Segall-Shapiro, D Wang, VK Mutalik, AP Arkin Nature Methods, 2012 | 88 | 2012 |
| Tandem repeat coupled with endonuclease cleavage (TREC): a seamless modification tool for genome engineering in yeast VN Noskov, TH Segall-Shapiro, RY Chuang Nucleic acids research 38 (8), 2570-2576, 2010 | 59 | 2010 |
| A genetically encoded and gate for cell-targeted metabolic labeling of proteins A Mahdavi, TH Segall-Shapiro, S Kou, GA Jindal, KG Hoff, S Liu, ... Journal of the American Chemical Society 135 (8), 2979-2982, 2013 | 39 | 2013 |
| TREC-IN: gene knock-in genetic tool for genomes cloned in yeast S Chandran, VN Noskov, TH Segall-Shapiro, L Ma, C Whiteis, C Lartigue, ... BMC genomics 15, 1-11, 2014 | 35 | 2014 |
| Mesophilic and hyperthermophilic adenylate kinases differ in their tolerance to random fragmentation TH Segall-Shapiro, PQ Nguyen, ED Dos Santos, S Subedi, J Judd, J Suh, ... Journal of molecular biology 406 (1), 135-148, 2011 | 34 | 2011 |
| Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein K Javanmardi, TH Segall-Shapiro, CW Chou, DR Boutz, RJ Olsen, X Xie, ... Cell host & microbe 30 (9), 1242-1254. e6, 2022 | 32 | 2022 |
| Selection for constrained peptides that bind to a single target protein AM King, DA Anderson, E Glassey, TH Segall-Shapiro, Z Zhang, ... Nature Communications 12 (1), 6343, 2021 | 22 | 2021 |
| The structure of a thermophilic kinase shapes fitness upon random circular permutation AM Jones, MM Mehta, EE Thomas, JT Atkinson, TH Segall-Shapiro, S Liu, ... ACS synthetic biology 5 (5), 415-425, 2016 | 14 | 2016 |
| Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality J Goike, CL Hsieh, A Horton, EC Gardner, F Bartzoka, N Wang, ... Biorxiv, 2021 | 10 | 2021 |
| SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode J Goike, CL Hsieh, AP Horton, EC Gardner, L Zhou, F Bartzoka, N Wang, ... Communications Biology 6 (1), 1250, 2023 | 4 | 2023 |
| Directed evolution of an orthogonal transcription engine for programmable gene expression in eukaryotes S Kar, EC Gardner, K Javanmardi, DR Boutz, R Shroff, AP Horton, ... bioRxiv, 2024 | | 2024 |
| TREC-IN: gene knock-in genetic tool for genomes cloned in yeast. SC Suchismita Chandran, VN Noskov, TH Segall-Shapiro, ML Ma Li, ... | | 2014 |
