Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay N Parker, MJ Turk, E Westrick, JD Lewis, PS Low, CP Leamon Analytical biochemistry 338 (2), 284-293, 2005 | 1465 | 2005 |
Folate-targeted chemotherapy CP Leamon, JA Reddy Advanced drug delivery reviews 56 (8), 1127-1141, 2004 | 821 | 2004 |
Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. CP Leamon, PS Low Proceedings of the National Academy of Sciences 88 (13), 5572-5576, 1991 | 821 | 1991 |
Folate-mediated targeting: from diagnostics to drug and gene delivery CP Leamon, PS Low Drug discovery today 6 (1), 44-51, 2001 | 548 | 2001 |
The folate receptor as a rational therapeutic target for personalized cancer treatment YG Assaraf, CP Leamon, JA Reddy Drug Resistance Updates 17 (4-6), 89-95, 2014 | 415 | 2014 |
Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential Y Lu, E Sega, CP Leamon, PS Low Advanced drug delivery reviews 56 (8), 1161-1176, 2004 | 349 | 2004 |
Synthesis and Biological Evaluation of EC20: A New Folate-Derived, 99mTc-Based Radiopharmaceutical CP Leamon, MA Parker, IR Vlahov, LC Xu, JA Reddy, M Vetzel, ... Bioconjugate chemistry 13 (6), 1200-1210, 2002 | 339 | 2002 |
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery CM Paulos, JA Reddy, CP Leamon, MJ Turk, PS Low Molecular pharmacology 66 (6), 1406-1414, 2004 | 316 | 2004 |
Engineering folate–drug conjugates to target cancer: from chemistry to clinic IR Vlahov, CP Leamon Bioconjugate chemistry 23 (7), 1357-1369, 2012 | 308 | 2012 |
Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivo CP Leamon, SR Cooper, GE Hardee Bioconjugate chemistry 14 (4), 738-747, 2003 | 277 | 2003 |
Endocytosis of folate-protein conjugates: ultrastructural localization in KB cells JJ Turek, PS Low Journal of cell science 106 (1), 423-430, 1993 | 268 | 1993 |
Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells. Contribution of translocation domain. CP Leamon, I Pastan, PS Low Journal of Biological Chemistry 268 (33), 24847-24854, 1993 | 251 | 1993 |
Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate JA Reddy, R Dorton, E Westrick, A Dawson, T Smith, LC Xu, M Vetzel, ... Cancer research 67 (9), 4434-4442, 2007 | 240 | 2007 |
Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors JA Reddy, C Abburi, H Hofland, SJ Howard, I Vlahov, P Wils, CP Leamon Gene therapy 9 (22), 1542-1550, 2002 | 240 | 2002 |
PRECEDENT: a randomized phase II trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum … RW Naumann, RL Coleman, RA Burger, EA Sausville, E Kutarska, ... Journal of clinical oncology 31 (35), 4400-4406, 2013 | 230 | 2013 |
Cytotoxicity of momordin-folate conjugates in cultured human cells. CP Leamon, PS Low Journal of Biological Chemistry 267 (35), 24966-24971, 1992 | 229 | 1992 |
Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide IR Vlahov, HKR Santhapuram, PJ Kleindl, SJ Howard, KM Stanford, ... Bioorganic & medicinal chemistry letters 16 (19), 5093-5096, 2006 | 215 | 2006 |
Targeting therapeutic and imaging agents to folate receptor positive tumors JA Reddy, VM Allagadda, CP Leamon Current pharmaceutical biotechnology 6 (2), 131-150, 2005 | 211 | 2005 |
Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells CP Leamon, PS Low Biochemical Journal 291 (3), 855-860, 1993 | 197 | 1993 |
Folate-targeted gene transfer in vivo HEJ Hofland, C Masson, S Iginla, I Osetinsky, JA Reddy, CP Leamon, ... Molecular Therapy 5 (6), 739-744, 2002 | 178 | 2002 |