Activin/Nodal signalling maintains pluripotency by controlling Nanog expression L Vallier, S Mendjan, S Brown, Z Chng, A Teo, LE Smithers, MWB Trotter, ... Oxford University Press for The Company of Biologists Limited 136 (8), 1339-1349, 2009 | 546 | 2009 |
Pluripotency factors regulate definitive endoderm specification through eomesodermin AKK Teo, SJ Arnold, MWB Trotter, S Brown, LT Ang, Z Chng, ... Genes & development 25 (3), 238-250, 2011 | 416 | 2011 |
The molecular functions of hepatocyte nuclear factors–In and beyond the liver HH Lau, NHJ Ng, LSW Loo, JB Jasmen, AKK Teo Journal of hepatology 68 (5), 1033-1048, 2018 | 246 | 2018 |
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors S Brown, A Teo, S Pauklin, N Hannan, CHH Cho, B Lim, L Vardy, ... Stem cells 29 (8), 1176-1185, 2011 | 218 | 2011 |
Activin and BMP4 Synergistically Promote Formation of Definitive Endoderm in Human Embryonic Stem Cells AKK Teo, Y Ali, KY Wong, H Chipperfield, A Sadasivam, Y Poobalan, ... STEM CELLS, 0 | 158 | |
SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells Z Chng, A Teo, RA Pedersen, L Vallier Cell stem cell 6 (1), 59-70, 2010 | 147 | 2010 |
Derivation of human induced pluripotent stem cells from patients with maturity onset diabetes of the young*[S] AKK Teo, R Windmueller, BB Johansson, E Dirice, PR Njolstad, E Tjora, ... Journal of Biological Chemistry 288 (8), 5353-5356, 2013 | 139 | 2013 |
Emerging use of stem cells in regenerative medicine AKK Teo, L Vallier Biochemical Journal 428 (1), 11-23, 2010 | 139 | 2010 |
Soluble factors secreted by T cells promote β-cell proliferation E Dirice, S Kahraman, W Jiang, A El Ouaamari, DF De Jesus, AKK Teo, ... Diabetes 63 (1), 188-202, 2014 | 92 | 2014 |
Proinflammatory cytokines induce endocrine differentiation in pancreatic ductal cells via STAT3-dependent NGN3 activation IA Valdez, E Dirice, MK Gupta, J Shirakawa, AKK Teo, RN Kulkarni Cell reports 15 (3), 460-470, 2016 | 83 | 2016 |
Metformin from mother to unborn child–Are there unwarranted effects? L Nguyen, SY Chan, AKK Teo EBioMedicine 35, 394-404, 2018 | 82 | 2018 |
Early developmental perturbations in a human stem cell model of MODY5/HNF1B pancreatic hypoplasia AKK Teo, HH Lau, IA Valdez, E Dirice, E Tjora, H Raeder, RN Kulkarni Stem Cell Reports 6 (3), 357-367, 2016 | 74 | 2016 |
PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells AKK Teo, N Tsuneyoshi, S Hoon, EK Tan, LW Stanton, CVE Wright, ... Stem Cell Reports 4 (4), 578-590, 2015 | 68 | 2015 |
Comparable generation of activin-induced definitive endoderm via additive Wnt or BMP signaling in absence of serum AKK Teo, IA Valdez, E Dirice, RN Kulkarni Stem cell reports 3 (1), 5-14, 2014 | 65 | 2014 |
New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism AKK Teo, AJ Wagers, RN Kulkarni Cell metabolism 18 (6), 775-791, 2013 | 65 | 2013 |
Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells BSJ Low, CS Lim, SSL Ding, YS Tan, NHJ Ng, VG Krishnan, SF Ang, ... Nature communications 12 (1), 3133, 2021 | 55 | 2021 |
Human duct cells contribute to β cell compensation in insulin resistance E Dirice, DF De Jesus, S Kahraman, G Basile, RWS Ng, A El Ouaamari, ... JCI insight 4 (8), 2019 | 51 | 2019 |
BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells LSW Loo, AAP Soetedjo, HH Lau, NHJ Ng, S Ghosh, L Nguyen, ... Cell death & disease 11 (5), 378, 2020 | 50 | 2020 |
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes E Dirice, S Kahraman, DF De Jesus, A El Ouaamari, G Basile, RL Baker, ... Nature metabolism 1 (5), 509-518, 2019 | 47 | 2019 |
Single-cell analyses of human islet cells reveal de-differentiation signatures AKK Teo, CS Lim, LF Cheow, T Kin, JA Shapiro, NY Kang, W Burkholder, ... Cell death discovery 4 (1), 14, 2018 | 45 | 2018 |