A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice TR Sampson, C Challis, N Jain, A Moiseyenko, MS Ladinsky, GG Shastri, ... elife 9, e53111, 2020 | 413 | 2020 |
Interactions of pathological hallmark proteins: Tubulin polymerization promoting protein/p25, β-amyloid, and α-synuclein J Oláh, O Vincze, D Virók, D Simon, Z Bozsó, N Tőkési, I Horváth, ... Journal of Biological Chemistry 286 (39), 34088-34100, 2011 | 172 | 2011 |
Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson’s disease I Horvath, P Wittung-Stafshede Proceedings of the National Academy of Sciences 113 (44), 12473-12477, 2016 | 164 | 2016 |
Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation I Horvath, CF Weise, EK Andersson, E Chorell, M Sellstedt, C Bengtsson, ... Journal of the American Chemical Society 134 (7), 3439-3444, 2012 | 140 | 2012 |
TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation L Tirián, E Hlavanda, J Oláh, I Horváth, F Orosz, B Szabó, J Kovács, ... Proceedings of the National Academy of Sciences 100 (24), 13976-13981, 2003 | 128 | 2003 |
TPPP/p25 promotes tubulin acetylation by inhibiting histone deacetylase 6 N Tőkési, A Lehotzky, I Horváth, B Szabó, J Oláh, P Lau, J Ovádi Journal of Biological Chemistry 285 (23), 17896-17906, 2010 | 122 | 2010 |
Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions O Vincze, N Tökési, J Oláh, E Hlavanda, Á Zotter, I Horváth, A Lehotzky, ... Biochemistry 45 (46), 13818-13826, 2006 | 100 | 2006 |
Interactions of enolase isoforms with tubulin and microtubules during myogenesis A Keller, J Peltzer, G Carpentier, I Horvath, J Olah, A Duchesnay, F Orosz, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (6), 919-926, 2007 | 85 | 2007 |
Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson’s disease: Ex vivo and in vitro studies I Horvath, IA Iashchishyn, RA Moskalenko, C Wang, SKTS Wärmländer, ... Journal of Neuroinflammation 15, 1-16, 2018 | 82 | 2018 |
Pro-inflammatory S100A9 protein as a robust biomarker differentiating early stages of cognitive impairment in Alzheimer’s disease I Horvath, X Jia, P Johansson, C Wang, R Moskalenko, A Steinau, ... ACS chemical neuroscience 7 (1), 34-39, 2016 | 74 | 2016 |
Immunochemical detection of α-synuclein autoantibodies in Parkinson’s disease: correlation between plasma and cerebrospinal fluid levels I Horvath, IA Iashchishyn, L Forsgren, LA Morozova-Roche ACS chemical neuroscience 8 (6), 1170-1176, 2017 | 66 | 2017 |
S100A9-driven amyloid-neuroinflammatory cascade in traumatic brain injury as a precursor state for Alzheimer’s disease C Wang, IA Iashchishyn, J Pansieri, S Nyström, O Klementieva, J Kara, ... Scientific Reports 8 (1), 12836, 2018 | 65 | 2018 |
Interaction of TPPP/p25 protein with glyceraldehyde‐3‐phosphate dehydrogenase and their co‐localization in Lewy bodies J Oláh, N Tőkési, O Vincze, I Horváth, A Lehotzky, A Erdei, E Szájli, ... FEBS letters 580 (25), 5807-5814, 2006 | 42 | 2006 |
Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro X Zhang, GR Walke, I Horvath, R Kumar, S Blockhuys, S Holgersson, ... Proceedings of the National Academy of Sciences 119 (37), e2206905119, 2022 | 40 | 2022 |
Macromolecular crowding modulates α-synuclein amyloid fiber growth I Horvath, R Kumar, P Wittung-Stafshede Biophysical Journal 120 (16), 3374-3381, 2021 | 38 | 2021 |
Biochemical evidence of both copper chelation and oxygenase activity at the histidine brace S Brander, I Horvath, JØ Ipsen, A Peciulyte, L Olsson, ... Scientific reports 10 (1), 16369, 2020 | 38 | 2020 |
Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation D Ribeiro, I Horvath, N Heath, R Hicks, A Forslöw, P Wittung-Stafshede Proceedings of the National Academy of Sciences 114 (42), 11127-11132, 2017 | 37 | 2017 |
Direct correlation between ligand-induced α-synuclein oligomers and amyloid-like fibril growth M Nors Pedersen, V Foderà, I Horvath, A van Maarschalkerweerd, ... Scientific reports 5 (1), 10422, 2015 | 36 | 2015 |
The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug I Horváth, V Harmat, A Perczel, V Pálfi, L Nyitray, A Nagy, E Hlavanda, ... Journal of Biological Chemistry 280 (9), 8266-8274, 2005 | 36 | 2005 |
Abundant fish protein inhibits α-synuclein amyloid formation T Werner, R Kumar, I Horvath, N Scheers, P Wittung-Stafshede Scientific reports 8 (1), 5465, 2018 | 35 | 2018 |