Prediction of solubility and permeability class membership: provisional BCS classification of the world’s top oral drugs A Dahan, JM Miller, GL Amidon The AAPS journal 11, 740-746, 2009 | 524 | 2009 |
Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs A Dahan, A Hoffman Journal of controlled release 129 (1), 1-10, 2008 | 434 | 2008 |
Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies S Ben-Shabat, L Yarmolinsky, D Porat, A Dahan Drug delivery and translational research 10, 354-367, 2020 | 376 | 2020 |
Food–drug interaction: grapefruit juice augments drug bioavailability—mechanism, extent and relevance A Dahan, H Altman European journal of clinical nutrition 58 (1), 1-9, 2004 | 339 | 2004 |
The solubility–permeability interplay and its implications in formulation design and development for poorly soluble drugs A Dahan, JM Miller The AAPS journal 14, 244-251, 2012 | 318 | 2012 |
A win–win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane … JM Miller, A Beig, RA Carr, JK Spence, A Dahan Molecular pharmaceutics 9 (7), 2009-2016, 2012 | 287 | 2012 |
The effect of different lipid based formulations on the oral absorption of lipophilic drugs: the ability of in vitro lipolysis and consecutive ex vivo intestinal permeability … A Dahan, A Hoffman European journal of pharmaceutics and biopharmaceutics 67 (1), 96-105, 2007 | 256 | 2007 |
The solubility–permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone A Dahan, JM Miller, A Hoffman, GE Amidon, GL Amidon Journal of pharmaceutical sciences 99 (6), 2739-2749, 2010 | 242 | 2010 |
Use of a Dynamic in Vitro Lipolysis Model to Rationalize Oral Formulation Development for Poor Water Soluble Drugs: Correlation with in Vivo Data and the … A Dahan, A Hoffman Pharmaceutical research 23, 2165-2174, 2006 | 231 | 2006 |
The solubility–permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation JM Miller, A Beig, BJ Krieg, RA Carr, TB Borchardt, GE Amidon, ... Molecular pharmaceutics 8 (5), 1848-1856, 2011 | 214 | 2011 |
Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs A Dahan, A Hoffman European journal of pharmaceutical sciences 24 (4), 381-388, 2005 | 195 | 2005 |
The solubility–permeability interplay and oral drug formulation design: Two heads are better than one A Dahan, A Beig, D Lindley, JM Miller Advanced drug delivery reviews 101, 99-107, 2016 | 191 | 2016 |
Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class … A Dahan, GL Amidon Molecular Pharmaceutics 6 (1), 19-28, 2009 | 168 | 2009 |
The solubility–permeability interplay when using cosolvents for solubilization: revising the way we use solubility-enabling formulations JM Miller, A Beig, RA Carr, GK Webster, A Dahan Molecular pharmaceutics 9 (3), 581-590, 2012 | 145 | 2012 |
Applications of polymers as pharmaceutical excipients in solid oral dosage forms N Debotton, A Dahan Medicinal research reviews 37 (1), 52-97, 2017 | 142 | 2017 |
Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations A Beig, R Agbaria, A Dahan PLoS One 8 (7), e68237, 2013 | 133 | 2013 |
Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting A Dahan, GL Amidon American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (2 …, 2009 | 130 | 2009 |
Accounting for the solubility–permeability interplay in oral formulation development for poor water solubility drugs: the effect of PEG-400 on carbamazepine absorption A Beig, JM Miller, A Dahan European journal of pharmaceutics and biopharmaceutics 81 (2), 386-391, 2012 | 121 | 2012 |
Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to … A Dahan, H Sabit, GL Amidon Drug Metabolism and Disposition 37 (10), 2028-2036, 2009 | 117 | 2009 |
Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein A Dahan, GL Amidon Pharmaceutical research 26, 883-892, 2009 | 116 | 2009 |