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Arik Dahan
Arik Dahan
Prof. of Pharmaceutics and Biopharmaceutics
Bestätigte E-Mail-Adresse bei bgu.ac.il
Titel
Zitiert von
Zitiert von
Jahr
Prediction of solubility and permeability class membership: provisional BCS classification of the world’s top oral drugs
A Dahan, JM Miller, GL Amidon
The AAPS journal 11, 740-746, 2009
5242009
Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs
A Dahan, A Hoffman
Journal of controlled release 129 (1), 1-10, 2008
4342008
Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies
S Ben-Shabat, L Yarmolinsky, D Porat, A Dahan
Drug delivery and translational research 10, 354-367, 2020
3762020
Food–drug interaction: grapefruit juice augments drug bioavailability—mechanism, extent and relevance
A Dahan, H Altman
European journal of clinical nutrition 58 (1), 1-9, 2004
3392004
The solubility–permeability interplay and its implications in formulation design and development for poorly soluble drugs
A Dahan, JM Miller
The AAPS journal 14, 244-251, 2012
3182012
A win–win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane …
JM Miller, A Beig, RA Carr, JK Spence, A Dahan
Molecular pharmaceutics 9 (7), 2009-2016, 2012
2872012
The effect of different lipid based formulations on the oral absorption of lipophilic drugs: the ability of in vitro lipolysis and consecutive ex vivo intestinal permeability …
A Dahan, A Hoffman
European journal of pharmaceutics and biopharmaceutics 67 (1), 96-105, 2007
2562007
The solubility–permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone
A Dahan, JM Miller, A Hoffman, GE Amidon, GL Amidon
Journal of pharmaceutical sciences 99 (6), 2739-2749, 2010
2422010
Use of a Dynamic in Vitro Lipolysis Model to Rationalize Oral Formulation Development for Poor Water Soluble Drugs: Correlation with in Vivo Data and the …
A Dahan, A Hoffman
Pharmaceutical research 23, 2165-2174, 2006
2312006
The solubility–permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation
JM Miller, A Beig, BJ Krieg, RA Carr, TB Borchardt, GE Amidon, ...
Molecular pharmaceutics 8 (5), 1848-1856, 2011
2142011
Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs
A Dahan, A Hoffman
European journal of pharmaceutical sciences 24 (4), 381-388, 2005
1952005
The solubility–permeability interplay and oral drug formulation design: Two heads are better than one
A Dahan, A Beig, D Lindley, JM Miller
Advanced drug delivery reviews 101, 99-107, 2016
1912016
Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class …
A Dahan, GL Amidon
Molecular Pharmaceutics 6 (1), 19-28, 2009
1682009
The solubility–permeability interplay when using cosolvents for solubilization: revising the way we use solubility-enabling formulations
JM Miller, A Beig, RA Carr, GK Webster, A Dahan
Molecular pharmaceutics 9 (3), 581-590, 2012
1452012
Applications of polymers as pharmaceutical excipients in solid oral dosage forms
N Debotton, A Dahan
Medicinal research reviews 37 (1), 52-97, 2017
1422017
Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations
A Beig, R Agbaria, A Dahan
PLoS One 8 (7), e68237, 2013
1332013
Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting
A Dahan, GL Amidon
American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (2 …, 2009
1302009
Accounting for the solubility–permeability interplay in oral formulation development for poor water solubility drugs: the effect of PEG-400 on carbamazepine absorption
A Beig, JM Miller, A Dahan
European journal of pharmaceutics and biopharmaceutics 81 (2), 386-391, 2012
1212012
Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to …
A Dahan, H Sabit, GL Amidon
Drug Metabolism and Disposition 37 (10), 2028-2036, 2009
1172009
Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein
A Dahan, GL Amidon
Pharmaceutical research 26, 883-892, 2009
1162009
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